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      community Minoxidil (topical) facial bloat

      in Minoxidil  9 upvotes 1 year ago
      Minoxidil can cause facial bloat, which some users manage by adjusting sodium intake or using it only on the scalp. Alternatives like finasteride or dutasteride are suggested for those concerned about facial changes.

      community A scary individual report of RU58841.

      in Research/Science  33 upvotes 1 year ago
      RU58841 caused severe side effects like heart palpitations and shortness of breath, leading the user to stop using it. Minoxidil and finasteride were effective without side effects, while RU58841's safety and effectiveness remain uncertain.

      community Oral minoxidil vs Topical Minoxidil w/ Retinoic acid

      in Minoxidil  5 upvotes 9 months ago
      Topical minoxidil with retinoic acid is effective but causes scalp irritation, leading the user to consider switching to 2.5mg oral minoxidil. Oral minoxidil may cause body hair growth and heart-related side effects, so it's advised to use it under medical guidance.

      community M23 on 1.1mg fin 5mg oral min for 4 months

      in Is this regrowth?  8 upvotes 1 week ago
      A 23-year-old male has been using 1.1mg finasteride and 5mg oral minoxidil for 4 months and is questioning if he has experienced hair regrowth. He reports some thickening of arm and facial hair but no serious side effects.

      community Doubtful of RU58441's negative effects

      in Research/Science  2 upvotes 9 months ago
      RU58841's potential side effects, particularly heart palpitations, are debated, with some attributing them to contamination with minoxidil. Users report mixed experiences, with some seeing no side effects and others cautioning about the lack of reliable data on RU58841's safety.

      community Connection between finasteride and nafld?

      in Research/Science  4 upvotes 1 year ago
      Finasteride may affect liver function and cortisol levels, potentially linking it to non-alcoholic fatty liver disease (NAFLD). More research is needed to understand this connection fully.

      community Regimen update - Added oral Minox and RU

      in Is this regrowth?  21 upvotes 2 years ago
      The user updated their hair loss treatment to include daily dutasteride, oral minoxidil, topical dutasteride with minoxidil and tretinoin, and RU58841. Commenters feel the extensive treatment is unnecessary for the user's level of hair loss.

      community How long should I wait to see if 5 mg oral min works for me? Titrated a couple weeks ago from 2.5 mg. Started at 1.25 mg about 300 days ago

      in Minoxidil  38 upvotes 1 year ago
      A 33-year-old user has been on finasteride for 10 years with great results and recently increased their oral minoxidil dose to 5 mg to improve hair thickness and possibly regrow hair. They are considering microneedling and a hair transplant to enhance their hairline and temples, despite already having significant improvement.

      community Pyrludimide (KX-826) or Breezula (clascoterone)

      in Treatment  9 upvotes 1 month ago
      The conversation is about hair loss treatments, specifically Pyrludimide (KX-826) and Breezula (clascoterone), with the user unable to tolerate finasteride and dutasteride. The user plans to use these treatments alongside minoxidil, considering the efficacy and availability of each option.

      community Can Pyrilutamide make hair loss worse?

      in Treatment  1 upvotes 5 months ago
      Pyrilutamide is being considered as an additional treatment to Minoxidil and Dutasteride for hair loss. Users report mixed results, with no evidence of it worsening hair loss.

      community 1 year of 1mg finasteride a day

      in Progress Pictures  305 upvotes 6 months ago
      The user has been taking 1mg of finasteride daily for a year, maintaining hair density without regrowth. They are considering oral minoxidil for regrowth, avoiding topical minoxidil due to its toxicity to cats, despite concerns about heart side effects.

      community Dutasteride 2.5 mg Progress (6 months)

      in Progress Pictures  161 upvotes 4 weeks ago
      A 49-year-old male switched from Finasteride to Dutasteride 2.5 mg daily, along with oral Minoxidil 5 mg, resulting in significant hair regrowth and stopping hair loss after six months. Despite initial side effects like adrenaline spikes and urinary issues, the user is satisfied with the results and plans to continue the treatment.

      community After 7 years on minoxidil 5% foam how bad is it? (28 year old male)

      in Is this regrowth? 1 month ago
      A 28-year-old male, who has been using minoxidil for 7 years, is concerned about hair miniaturization and is considering adding pyrilutamide, alfatradiol, and nizoral to his regimen after experiencing side effects from finasteride. Despite concerns, others reassure him that his hairline appears normal for his age, and he is likely around a Norwood 1.5.

      community Fin 1 mg oral 1x/day + min topical 2x/day, 4 months progress

      in Progress Pictures 3 years ago
      Anxious_Bee_67's 4 month progress with a hair loss treatment regimen of 1 mg oral finasteride once a day and topical minoxidil twice a day, which has brought "hope" to others who are fighting the Norwood Reaper. Replies include encouragement for further progress and advice on other treatments that can be used in conjunction with the current ones.

      community A vehicle for powdered melatonin

      in Treatment  6 upvotes 4 years ago
      The conversation is about using topical melatonin for hair loss and seeking advice on a safe mixing solution or pre-mixed product. Specific treatments mentioned are minoxidil, finasteride, and RU58841.

      community Is there any new drug that looks promising ?

      in Research/Science  24 upvotes 2 years ago
      The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

      community GT20029. Kintor Pharma’s Product

      in Research/Science  12 upvotes 3 years ago
      The conversation discusses GT20029, a compound by Kintor Pharma that degrades androgen receptors and is in trials, with potential as a hair loss cure. Another promising treatment mentioned is an antibody that blocks prolactin and has shown positive results in macaques.

      community Alfatradiol causing shedding ?

      in Treatment  1 upvotes 1 year ago
      The user experienced a sudden decrease in hair density after starting alfatradiol while already using finasteride. Another user mentioned that initial shedding can occur with hair loss treatments, but it may not last long.

      community Control your blood pressure - for me this was my root issue

      in Treatment  8 upvotes 11 months ago
      Managing blood pressure can help with hair loss, as seen with the use of medications like Cialis and oral minoxidil, which improved hairline and blood pressure. Lifestyle changes, such as reducing stimulant use and adjusting testosterone replacement therapy (TRT) doses, also play a role in addressing hair loss and overall health.

      community Progress at 4 month mark dut/min

      in Progress Pictures  10 upvotes 4 months ago
      A 24-year-old is using 1 mg oral dutasteride and 1 mg oral minoxidil daily, along with monthly mesotherapy including zinc, dutasteride, minoxidil, biotin, and panthenol, to treat hair loss. The user is considering increasing the minoxidil dose but will consult with their doctor first.

      community New angles to attack beyond DHT

      in Research/Science  4 upvotes 1 year ago
      Exploring hair loss treatments beyond DHT, including Minoxidil, pyruvate, Gt20029 targeting androgen receptors, and vasodilators. Other options like Kx826, adenosine signaling, growth factor topicals, and microneedling are also discussed.