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      community A concern regarding the upcoming androgen degrader drug GT20029

      in Chat  11 upvotes 1 year ago
      GT20029 is a topical treatment that degrades androgen receptors to prevent hair thinning and loss, potentially offering fewer side effects than systemic treatments like finasteride. Concerns include its impact on hair texture and potential systemic effects, with market availability speculated in 3 to 5 years.

      community Fin/dut ONLY users, this has been my experience so far

      in Finasteride/Dutasteride  97 upvotes 1 year ago
      The user has been using finasteride for hair loss since January 2023, initially seeing improvement but now experiencing increased thinning. They are considering other factors like thyroid and insulin resistance and are seeking advice from long-term finasteride users, while some suggest trying dutasteride, minoxidil, or consulting a dermatologist for further evaluation.

      community ED from 1 month DUT

      in General  88 upvotes 11 months ago
      A 32-year-old male experienced reduced libido and erectile difficulties after taking Minoxidil and Dutasteride for hair loss. He stopped the treatment and plans to consult his doctor, seeking similar experiences from others.

      community Another blow to the cursed baldness

      in Research/Science  91 upvotes 8 months ago
      A South Korean company, Therazyne, has developed a promising hair loss treatment using a WNT chain surrogate that binds to Frizzled 7, with human follicle testing expected soon. Current treatments like minoxidil and finasteride are not seen as cures, and while optimism exists for future solutions like PP405, approval processes are lengthy.

      community DHT and 5AR respect post, it's importance within the brain

      in Research/Science  111 upvotes 2 years ago
      The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

      community 16month progress on crazy stack

      in Finasteride/Dutasteride  8 upvotes 2 years ago
      The user has been using a strong combination of hair loss treatments for 16 months, including Finasteride, Minoxidil, Dutasteride, and RU-58841, but their hair loss has worsened. They're questioning whether their high testosterone levels or residual scalp DHT are causing further hair loss, with a reply suggesting that even small amounts of DHT can cause hair loss if one is sensitive to it.

      community Since there is so much hype for cosmeRNA and HMI-115...

      in Chat  44 upvotes 3 years ago
      Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.

      community Topical finasteride has affected my hormones

      in Finasteride/Dutasteride  25 upvotes 2 years ago
      A 21-year-old experienced hormone changes after using self-made topical finasteride for hair loss, including a 20% decrease in DHT, a 47% increase in testosterone, and a 39% increase in estradiol. The user previously used minoxidil and microneedling but is now seeking ways to balance hormones, possibly through supplements or dosage adjustments.

      community 3 months in on oral Dut/Min. The shed is REAL

      in Finasteride/Dutasteride  46 upvotes 1 month ago
      The user is experiencing significant hair shedding after three months on oral Dutasteride, Minoxidil, and Vitamin D3, but remains hopeful as shedding can indicate treatment effectiveness. They consider adding topical Minoxidil and dermal needling, while others advise patience.

      community Whey Protein can cause hairloss in men with AGA as per a doctor

      in Research/Science  63 upvotes 5 months ago
      Whey protein may slightly increase hair loss in men with androgenetic alopecia (AGA) due to elevated IGF-1 and testosterone levels, but the effect is minimal compared to treatments like finasteride and dutasteride. Many users argue that whey protein's impact on hair loss is negligible and that maintaining a healthy lifestyle is more important.

      community Trestolone (MENT) as a nuclear treatment

      in Treatment  99 upvotes 3 years ago
      Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

      community 30M, 15 months Dut 0,5 and prp, what now?

      in General  202 upvotes 9 months ago
      A 30-year-old male has been experiencing hair loss despite using Dutasteride 0.5mg and PRP for 15 months, with no success. He is considering a hair transplant but is advised to stabilize hair loss first and explore other treatments like topical Minoxidil or combined therapies.

      community PRP ( PLATELET-RICH-PlASMA) for hair loss

      in Treatment  1 upvotes 2 years ago
      A 27-year-old male experiencing hair loss post-Covid is considering PRP (platelet-rich plasma) therapy. He's seeking personal experiences about the process, particularly regarding pain levels, despite his dermatologist's assurance of using local anesthesia.

      community TE Shedding for nearly 10 months now

      in Minoxidil  3 upvotes 1 year ago
      A 20-year-old male experienced significant hair shedding for nearly 10 months, despite using finasteride, oral minoxidil, and ketoconazole, and is concerned about chronic telogen effluvium. He has been supplementing with vitamins and minerals but remains unsure of the cause.