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GlossaryAnticancer

inhibits the growth and spread of cancer cells

Anticancer, also known as antineoplastic or antitumor, refers to substances or treatments that inhibit the growth and spread of cancer cells. These agents work through various mechanisms, such as damaging the DNA of cancer cells, inhibiting cell division, or blocking the blood supply to tumors, ultimately aiming to eliminate or reduce the malignancy.

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community Will previous use of anti androgens affect finasteride use?

in Finasteride/Dutasteride 1 upvotes 10 months ago

The user is concerned about whether previous use of anti-androgens like fluridil, which caused side effects, will affect future use of finasteride. They have used finasteride briefly in the past and are considering using it again.

community Anti-androgen use causing testicular pain?

in Finasteride/Dutasteride 5 upvotes 9 months ago

Switching from topical finasteride to oral Dutasteride and using Fluridil caused persistent testicular discomfort. The discomfort did not subside after stopping Fluridil, raising concerns about Dutasteride's role.

community Affordable anti androgens in India?

in Treatment 4 upvotes 1 year ago

The conversation discusses hair loss treatments, specifically the use of anti-androgens like RU58841 and Pyrilutamide, which are expensive in India. Alternatives like spironolactone and concerns about the effectiveness of finasteride and dutasteride are also mentioned.

community Is There Any Chance Of Cancer In Follicle Neogenesis through Microneedling?

in Microneedling 18 upvotes 6 years ago

The conversation discusses concerns about the potential risk of cancer from creating new hair follicles through microneedling, due to stem cell division. Specific treatments mentioned include microneedling, caffeine-containing anti-hair loss shampoos, and other unspecified topicals.

community If RU58841 is such an effective anti androgen

in Research/Science 46 upvotes 2 years ago

RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.

community (Europe) looking for advice on topical anti androgen use

in Treatment 3 upvotes 9 months ago

The user is using finasteride, minoxidil, and ciclopirox shampoo for hair loss and is considering adding a topical anti-androgen like RU58841, Clacosterone, or KX286. They have scheduled a hair transplant and are concerned about the cost and effectiveness of future treatments.

community Seeking Advice on Norwood 3 Hairline at Age 15

in Basic Questions 533 upvotes 6 months ago

A 15-year-old is concerned about hair loss, possibly at Norwood 2 or 3, and is using shampoos and conditioners recommended by a trichologist. Suggestions include considering topical minoxidil and consulting a doctor about topical anti-DHT treatments like finasteride or RU58841, but avoiding 5-alpha-reductase inhibitors at this age.

community Research behind RU-58642? Has anyone heard of this?

in Research/Science 1 upvotes 11 months ago

RU-58642 is a powerful anti-androgen that was not developed further, possibly due to safety concerns or financial reasons. RU58841 is a topical alternative, but it is less effective than finasteride and dutasteride, and its long-term effects are not well-studied.

community I just went to a dermatologist and there were many red flags about him.

in Treatment 13 upvotes 3 years ago

A user visited a dermatologist for hair loss concerns and was prescribed a hair lotion called "Lotion revolotion evdermia," which is meant for hair toning, hydration, and anti-aging, not regrowth. The user found the dermatologist's behavior and the prescription to be questionable.

community help me out gng need sources of cb , pyrilutamide , fluridil , aflatridol etc

in Product 4 upvotes 2 weeks ago

The conversation is about finding sources for topical anti-androgens like CB, pyrilutamide, fluridil, and aflatridol for hair loss treatment. The user is considering using CB powder from IndiaMart but is concerned about side effects from finasteride and minoxidil.

community Recommendations for topical antiandrogens

in Treatment 2 upvotes 5 months ago

The conversation is about adding a topical anti-androgen to a hair loss treatment regimen that includes dutasteride and oral minoxidil. The user is considering topical finasteride or dutasteride, Nizoral shampoo, KX-826, and topical spironolactone, while avoiding RU58841 due to safety concerns.

community The story of RU58841/PSK3841

in Research/Science 1 year ago

RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

community FOL005 claims it's better than Finasteride and Minoxidil.

in Technology 184 upvotes 1 year ago

FOL-005 claims to be more effective than Minoxidil and Finasteride but lacks anti-DHT properties, leading to potential reduced efficacy over time. Concerns are raised about misleading marketing and the safety of alternative treatments like Pyrilutamide and Clascoterone.

community If inhibiting DHT can cause Prolactin to increase then is the opposite also true?

in Treatment 5 upvotes 2 years ago

The conversation discusses using P5P (Vitamin B6) supplements to reduce elevated Prolactin levels and concerns about its potential effect on increasing DHT levels. The user is not currently using finasteride or any anti-androgens.

community Does ketoconazole reduce systemic DHT by much?

in Treatment 6 upvotes 10 months ago

Ketoconazole shampoo does not significantly reduce systemic or scalp DHT levels and is mainly used for its anti-fungal and anti-inflammatory effects. It is not a replacement for finasteride, which is recommended by some users despite concerns about side effects.

community Kintor Pharmaceutical’s KX-826 Shows Promising Results in Hair Loss Study

in Research/Science 17 upvotes 1 year ago

Kintor Pharmaceutical's KX-826 shows promising results for hair loss treatment. Users discuss the use of anti-androgens like spironolactone and RU58841, noting concerns about concentration and safety.

community Bicalutamide and muscles growth

in Female 7 upvotes 1 year ago

A 30-year-old woman with androgenetic alopecia is considering bicalutamide to slow hair loss but is concerned about its impact on muscle growth due to its anti-androgen effects. Alternatives suggested include dutasteride, spironolactone, RU58841, and minoxidil, with concerns about bicalutamide's side effects.

community Starting Propecia with pre-existing erecticle dysfunction

in Finasteride 4 upvotes 9 years ago

A 19-year-old with diffuse hair thinning and erectile dysfunction is considering starting Propecia (finasteride) while already using a minoxidil solution with anti-androgens. Concerns are raised about the psychological nature of erectile dysfunction and the potential systemic effects of anti-androgens, with suggestions to address porn addiction and consult a doctor about hormone therapy.

community Is Sulforaphane really an option?

in Chat 9 upvotes 4 years ago

The conversation discusses the potential benefits of Sulforaphane for hair growth, with a suggestion to grow broccoli sprouts for the best results. One user doubts its effectiveness for hair loss but notes its anti-cancer and hormetic benefits.

community Rosemary Oil for inflammatory hairloss? Recommendations?

in Treatment 4 upvotes 9 months ago

A user with seborrheic dermatitis and traction alopecia is seeking alternatives to minoxidil for hair loss, considering rosemary oil for its anti-inflammatory properties. They express concerns about potential side effects and effectiveness of various treatments, including rosemary oil, caffeine, and Redensyl.

community Low dose of fin 2x per week after stopping 1mg daily

in Finasteride/Dutasteride 1 upvotes 1 year ago

The user experienced side effects from daily finasteride and reduced the dosage to 0.25mg twice a week while continuing minoxidil. They are considering topical anti-androgens but are concerned about application difficulties and potential side effects.

community Case study: 1mo progress microneedling + minox, no fin.

in Microneedling 8 upvotes 5 years ago

A user shared their experience with microneedling and minoxidil for hair loss, avoiding finasteride due to concerns about systemic hormone effects. They reported slight hair regrowth after one month and plan to continue the regimen, noting improvements in skin sensitivity and managing dandruff with anti-dandruff shampoo.

community Any help with female hair loss?

in Female 2 upvotes 6 months ago

A 20-year-old female with PCOS is experiencing hair loss and excessive facial hair. She is using ketoconazole and caffeine shampoos, microneedling, and considering anti-androgens like finasteride, but is cautious about minoxidil due to facial hair concerns.

community Topical anti-androgen availability in Australia

in Product 1 year ago

Availability of topical anti-androgens, especially RU58841, in Australia. Issues with customs seizures and lack of credible local sources.

community Minoxidil and concern about cats

in Minoxidil 5 upvotes 10 months ago

Minoxidil is highly toxic to cats, and even small amounts can be fatal. The user decided against using topical minoxidil due to the risk to their cats and considered oral minoxidil and ketoconazole shampoo as alternatives.

community One year anti androgen update CROWN

in Finasteride/Dutasteride 338 upvotes 2 years ago

User used Finasteride, Dutasteride, and Minoxidil for one year to treat hair loss. They discussed possibly trying RU58841 or pyrilutamide in the future.

community Kintor develop GT20026 Anti-Androgen receptor drug with NO SIDES

in Treatment 17 upvotes 5 years ago

The conversation discusses GT20029, a new topical drug for hair loss and acne without notable side effects, which has been accepted for investigational use in China. Some users express skepticism about the legitimacy of the company and the potential for other drugs like RU58841 to be developed due to patent expiration and lack of profitability.

community 23-Year-Old Trans Male: Concerns About Minox and Finasteride for Hair Loss

in General 298 upvotes 9 months ago

A 23-year-old trans male is concerned about hair loss and is considering treatments like topical and oral minoxidil and finasteride. They are worried about the effects on their pet and hormone balance and are seeking affordable options within their existing medical team.

community The Biggest Concern That I Have For Oral Minoxidil: Cardiac Hypertrophy

in Minoxidil 27 upvotes 2 years ago

Oral minoxidil can cause serious heart issues like cardiac hypertrophy and arrhythmias, prompting some users to reduce dosage or switch to topical treatments. Despite significant hair regrowth, side effects such as shortness of breath and chest pains are common concerns.

community Finasteride and “anti-aging” effects

in Treatment 218 upvotes 8 months ago

Finasteride may help users look younger by suppressing DHT, affecting skin and hair. Users also emphasize skincare, sunscreen, and lifestyle for maintaining a youthful appearance.