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Topical dutasteride may not significantly reduce hair loss and could potentially increase testosterone, leading to further hair loss. Users report side effects like mood changes, sleep issues, and severe side effects, with no significant progress in hair regrowth.

A person experienced severe sexual side effects, including loss of libido and erectile dysfunction, after using finasteride and dutasteride for hair loss. They stopped the medications and sought advice, but recovery was slow and uncertain.

The user experienced side effects from oral minoxidil and is seeking alternatives like Stemoxydine, Aminexil, and Redensyl + Procapil. They have been using finasteride for four years and are considering other treatments due to concerns about side effects.

A 25-year-old uses oral minoxidil, dutasteride, and a shampoo with minoxidil and ketoconazole for hair loss, experiencing progress and increased body hair. Users discuss the effectiveness of these treatments, with some suggesting that dutasteride is primarily responsible for hair thickening.

The user applies 2ml of a lotion containing 5% minoxidil, 0.3% finasteride, hydrocortisone butyrate, and cetirizine before bed, but it leaves a residue on the scalp. Another user suggests reducing the amount to 1ml, as 2ml results in a high finasteride dosage.

The conversation discusses the use of vasodilators like Minoxidil, L-arginine, and Niacin for hair regrowth, with Minoxidil causing intolerable side effects for the original poster. It also highlights that certain medications, including Lisinopril, antidepressants, and statins, can cause hair loss.

Combining Minoxidil with Finasteride or RU58841 may cause interference, irritation, or reduced absorption. It might be better to apply one topical at a time and wait an hour before applying another.

The user experienced hair regrowth with finasteride and minoxidil but faced libido issues, leading them to try alternatives like novamaine and a low-dose finasteride/minoxidil solution, which still caused side effects. They are considering reducing the solution's volume, stopping finasteride, or using minoxidil alone, while others suggest alternatives like dutasteride or clascoterone.

Higher doses of dutasteride, such as 2.5mg, are more effective at reducing scalp DHT than 0.5mg, but are costly and inconvenient. A 1mg dose is considered a more affordable and practical option, though its efficacy is uncertain.

A user reports experiencing insomnia as a side effect of taking finasteride for hair loss, which takes 1 to 2 hours to fall asleep and results in only about 5 hours of sleep per night. They suspect the cause is related to the downregulation of neurosteroids due to finasteride.

The conversation discusses Melatonin's potential benefits for AGA and a product called "Asatex" by ASATONA AG. The company was uncooperative when contacted for purchase inquiries.

Oral minoxidil may cause temporary facial puffiness, leading to a perception of accelerated aging, but it doesn't cause actual aging. Concerns about hair loss and treatments like minoxidil and finasteride are discussed, with suggestions to use tretinoin and sunscreen to mitigate potential side effects.

Crushing spironolactone pills and combining them with minoxidil for topical application may be effective for hair loss, with the addition of finasteride suggested. Adding rosemary and peppermint oils can help mask the unpleasant smell.

Clascoterone cream was submitted for review to Health Canada in August 2022, with hopes of approval within 3-6 months. It may potentially enhance finasteride's effects for hair loss treatment.

Fluridil is hard to obtain and only available in Slovakia and Czechia, with no systemic side effects but possibly limited effectiveness compared to finasteride. The original poster is using finasteride and minoxidil without success and is considering trying fluridil despite its cost.

Clascoterone (Breezula) showed positive results for treating hair loss without affecting cortisol levels. Opinions vary, with some users optimistic about its potential and others critical of its effectiveness compared to existing treatments like finasteride.

A user started using RU58841 for hair loss and experienced anxiety and physical discomfort. Other users suggested avoiding the treatment due to similar side effects and recommended alternative treatments like pyri.

Topical Dutasteride 0.05% twice a week and Dutasteride Mesotherapy 0.01% once a week showed noticeable improvement in hair loss over six months without side effects. The user plans to add Minoxidil tablets 2.5mg daily to their treatment.

Finasteride can increase estrogen levels, causing dizziness and nausea. Users discuss adjusting treatment and diet, and explore alternatives for hair loss management.

The user experienced bladder and prostate discomfort after taking finasteride and stopped the medication, but symptoms returned upon resuming at a lower dose. The doctor suggested trying dutasteride as an alternative.

Topical minoxidil with retinoic acid is effective but causes scalp irritation, leading the user to consider switching to 2.5mg oral minoxidil. Oral minoxidil may cause body hair growth and heart-related side effects, so it's advised to use it under medical guidance.

A 28-year-old is experiencing hair loss despite using treatments like oral minoxidil, finasteride, and high-dose dutasteride (2.5 mg). They suspect lichen planus might be contributing to the issue and plan to continue treatment while monitoring progress.

Cosmo Pharmaceuticals has enrolled about 850 out of 1400 patients for their phase 3 clinical trials of clascoterone (Breezula) and claims to be on schedule. The conversation is about hair loss treatments.

The user is considering adding an anti-androgen, RU58841, to their current hair loss treatment routine due to receding hair. They are also contemplating waiting for Breezula or Pyrilutamide to become more affordable.

A woman with androgenic alopecia has been using birth control, spironolactone, finasteride, and oral minoxidil for hair loss. She sought to change her medications to dutasteride and bicalutamide, but her new dermatologist refused to prescribe them for off-label use.

The conversation discusses using Duodart (dutasteride + tamsulosin) for hair loss, with side effects like frequent urination and ejaculation issues leading to discontinuation. The user switched to German Avodart and experienced mood and erection side effects, considering adjusting the dosage to three times a week.

Delayed release oral minoxidil is seen as a promising advancement for hair loss treatment, offering safer, higher doses and more consistent hair follicle stimulation compared to current options. However, it is not expected to replace finasteride or dutasteride, as it does not prevent androgenetic alopecia.

The user is allergic to minoxidil and seeks alternatives for hair regrowth. They have been using finasteride for two years, which stopped hair loss but did not promote regrowth.

Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

The user experienced side effects from finasteride and is considering switching to dutasteride, while also using pyrilutamide to protect hair follicles. They are seeking advice on whether to add RU58841 to their regimen.