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      community Trichosol, polyethylene glycol, and DMSO

      in Minoxidil  3 upvotes 1 year ago
      The user experiences irritation from alcohols in minoxidil and is considering alternatives like trichosol mixed with polyethylene glycol or DMSO. They seek advice on the best nonirritating option.
      “Mature Hairline” or Genuine AGA?

      community “Mature Hairline” or Genuine AGA?

      in Basic Questions  62 upvotes 1 week ago
      A 33-year-old male is experiencing thinning at the temples and hairline, with increased shedding over the past year. The user suspects androgenetic alopecia (AGA) despite AI suggesting a maturing hairline.

      community PTD-DBM Update: Q&A With Dr. Kang-Yell Choi

      in Treatment  14 upvotes 6 years ago
      PTD-DBM is being explored for hair regrowth by targeting CXXC5, with clinical trials expected after pre-clinical studies. Users express anticipation and skepticism about its effectiveness.

      community Second shed, non-stop flaking, itching

      in Treatment  12 upvotes 1 year ago
      The user is experiencing a second hair shedding phase and increased flaking and itching while using minoxidil 5% nightly and microneedling every two weeks, with needle length increasing over time. Other users suggest the hair loss may continue without the use of finasteride.

      community The mechanism of androgenic alopecia

      in Research/Science  33 upvotes 6 months ago
      DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

      community Kind of cool early Fin + Min update

      in Finasteride/Dutasteride  39 upvotes 1 year ago
      The user noticed new dark hairs growing in previously bald areas after using oral finasteride and minoxidil for a month. They are pleased with the progress and find it interesting, even though they are content with a shaved head.

      community 7 Months in minoxidil treatement: I need your help! Is it getting worse?

      in Female  1 upvotes 3 months ago
      A 25-year-old woman using minoxidil 2% for hair loss is experiencing faster hair growth and new baby hairs but continues to lose hair and see miniaturization. Suggestions include switching to minoxidil 5%, checking vitamin levels, using Nizoral, and considering a DHT blocker.

      community 4 months into micro, got worse on the areas I needle

      in Microneedling  10 upvotes 1 year ago
      The user reports that after 4 months of microneedling, 10 months of Minoxidil, 2 years of finasteride, and using ketoconazole 3 times a week, their hair has become less dense in the treated areas. Despite initial shedding and continued treatment, they have not seen improvement and feel their body is resistant to the medications.

      community Is this regrowth or vellus hairs?

      in Is this regrowth?  1 upvotes 1 year ago
      A user with long-term hair loss has been using topical minoxidil, finasteride, RU58841, ketoconazole, and dermastamping for 8 months. They are unsure if the new hairs are miniaturized or vellus.

      community 5mg min 0.5mg dut - temple regrowth but ravaged crown? 28M

      in Progress Pictures  39 upvotes 1 month ago
      A 28-year-old male is experiencing temple regrowth but crown thinning while using 5mg minoxidil and 0.5mg dutasteride. The shedding phase is seen as a positive sign of treatment effectiveness, with expectations of noticeable improvements around 6 to 12 months.

      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  91 upvotes 3 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

      community 7 Month Hair Progress (0.5 mg dut only, diffuse thinning)

      in Progress Pictures  716 upvotes 2 years ago
      An 18-year-old male switched from topical finasteride and minoxidil to oral dutasteride for diffuse hair loss and saw improvement without side effects, despite experiencing scalp itch and shedding. Commenters noted significant hair regrowth and were surprised by his young age and appearance.

      community Six Month Progress Update - Hair Darker than Ever

      in Progress Pictures  164 upvotes 6 months ago
      The user experienced significant hair darkening and progress in hair regrowth over six months using 5% topical minoxidil, 5 mg oral minoxidil, 1 mg finasteride, and weekly microneedling. No side effects were reported from these treatments.

      community 10 months CB and Oral Minoxidil

      in Progress Pictures  112 upvotes 1 year ago
      A person with Alopecia Areata on their beard is using CB-03-01 and oral minoxidil for treatment. Some users question the effectiveness of CB-03-01 for beard hair, suggesting that minoxidil alone may be responsible for any observed hair growth.

      community TDM-105795 phase 2 results are in!

      in Research/Science  29 upvotes 2 years ago
      TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

      community If dutesteride and oral minoxidil doesn’t work that’s it right?

      in Treatment  20 upvotes 1 year ago
      A user is experiencing continued hair loss despite using 0.5mg dutasteride and 2.5mg minoxidil, and is seeking advice on why the treatments aren't working and how to address potential androgen receptor sensitivity. Replies suggest getting tested and considering scalp micropigmentation (SMP).

      community 36 year old. 18month moxidil and fin.

      in Progress Pictures  732 upvotes 1 year ago
      A 36-year-old has been using 1mg oral finasteride daily and minoxidil foam twice daily for 18 months, experiencing significant hair regrowth with no side effects. Initial shedding occurred, but noticeable improvements began around 11 months, with major changes by 16 months.

      community Dutasteride UPDATE (female) *sixth month*

      in Progress Pictures  17 upvotes 3 years ago
      A female user in her mid-20s with androgenetic alopecia and suspected telogene effluvium who has been taking Dutasteride, Spironolactone, Minoxidil, Dermarolling, Ketoconazol shampoo, and Yaz contraception for her hair loss for the past 6 months. She had a small shed during this time that she believes to be stress related.

      community From Perfect Hair to This: 2 Years of Chronic TE + Unmasked AGA.

      in Treatment  5 upvotes 6 days ago
      A 25-year-old is experiencing chronic telogen effluvium (TE) and androgenetic alopecia (AGA) after surgery, using finasteride, red light therapy, and supplements, and considering oral minoxidil despite heart concerns. They are unsure whether to start minoxidil before or after an upcoming surgery, which may trigger another hair shed.