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      community Does ketoconazole reduce systemic DHT by much?

      in Treatment  6 upvotes 10 months ago
      Ketoconazole shampoo does not significantly reduce systemic or scalp DHT levels and is mainly used for its anti-fungal and anti-inflammatory effects. It is not a replacement for finasteride, which is recommended by some users despite concerns about side effects.

      community How do you guys dilute topical finasterid?

      in Product  2 upvotes 3 years ago
      Mixing topical finasteride with essengen f and stemoxydine creates 0.25mg dose in 2ml. Minoxidil max suggests mixing 8.5ml essengen f with 60ml solvent for 0.25mg dose in 1ml.

      community Lowest Effective RU58841 Dose?

      in Treatment  4 upvotes 1 year ago
      RU58841 is discussed as a hair loss treatment, with users considering lower doses like 2.5% to reduce costs. Some users suggest that if already blocking DHT, lower doses might still be effective unless there's high sensitivity to DHT.

      community Piroctone Olamine and Ketoconazole

      in Ketoconazole  8 upvotes 2 years ago
      Piroctone olamine and ketoconazole are both effective for reducing dandruff and hair shedding, with potential benefits for hair thickness and scalp health. Piroctone olamine may be as effective or better than ketoconazole in certain conditions, yet it is often overlooked.

      community Considering Switching from 0.25% Topical Finasteride to Oral After 8 Months

      in Finasteride  70 upvotes 8 months ago
      The user has been using 0.25% topical finasteride for eight months with slight improvement and is considering switching to oral finasteride for convenience and potentially better results. Increasing the topical concentration to 0.33% or 0.5% is also an option, but oral finasteride may have more systemic side effects.

      community Is 2.5 mg dut really more effective than .5?

      in Finasteride/Dutasteride  10 upvotes 2 years ago
      A user on .5 mg of dutasteride for hair loss saw no improvement and is considering increasing to 2.5 mg but is unsure of its effectiveness. Another user mentioned that 2.5 mg reduces scalp DHT more and increases hair count more than .5 mg, but the cost and side effects should be considered.

      community What to look Forward to in 2025

      in Research/Science  20 upvotes 1 year ago
      Hair loss treatments are advancing, with Coegin Pharma's FOL005 expected this year and Breezula potentially later. Pyrilutamide is available but not very effective, while Kintor's products face skepticism; traditional treatments like finasteride and minoxidil remain dominant.

      community Formula 82f and Keto?

      in Minoxidil  70 upvotes 1 year ago
      A user is using a topical treatment called Formula 82f, which contains finasteride, minoxidil, and a steroid, along with Ketoconazole shampoo for hair loss. They are considering whether to switch to oral medication for better results.

      community Mixing topical minoxidil and alfatradiol

      in Treatments  39 upvotes 9 months ago
      Mixing minoxidil and alfatradiol in one bottle may affect their effectiveness due to potential stability issues. It's recommended to apply them separately for full benefits.

      community 5 month progress [0.5mg Dut, 5% Min]

      in Progress Pictures  715 upvotes 1 year ago
      A user shared their 5-month hair regrowth progress using 0.5mg Dutasteride daily and 5% Minoxidil foam twice daily, reporting significant improvement despite initial shedding. Other users discussed their experiences with similar treatments, noting varied results and side effects, with some emphasizing the need for long-term commitment to maintain hair growth.

      community Topical bimatoprost or latanoprost

      in Product  11 upvotes 1 year ago
      OP is considering adding topical bimatoprost or latanoprost to their hair loss treatment, which already includes oral minoxidil, and is seeking reliable sources for these products. Users discuss the effectiveness and sourcing of these treatments, with some using bimatoprost for both hairline and eyelashes, and others planning to use latanoprost mixed with finasteride.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  134 upvotes 2 years ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Compounded minox + tretinoin topical

      in Product  2 upvotes 1 year ago
      A user is seeking recommendations for a minoxidil and tretinoin topical solution, including dosage and purchase locations in the US. They are looking for effective hair loss treatments.

      community CB-03-01 supposed hair loss cure

      in Treatment  9 upvotes 5 years ago
      The conversation discusses why CB-03-01, a potential hair loss treatment, isn't widely discussed despite evidence of its effectiveness and safety. Some users mention other treatments like melatonin, procianidin b2, and RU58841, debating their effectiveness and safety.

      community They've stopped selling this in the UK

      in Ketoconazole  6 upvotes 1 year ago
      Ketoconazole is no longer sold in the UK, and pharmacies have replaced it with non-ketoconazole options. Users are discussing its availability and possible alternatives.

      community Better then Minoxidil( at least for me and my family)

      in Treatment  44 upvotes 2 years ago
      Capronium Chloride and Trichoxidil are suggested as better alternatives to Minoxidil for hair growth without heart side effects. The Japanese Dermatological Association recommends topical Minoxidil over Capronium Chloride.

      community Question about making a solution of RU58841

      in Treatment  1 upvotes 3 years ago
      The conversation is about making a solution of RU58841 using propanediol instead of propylene glycol due to skin irritation. The user seeks advice on whether this substitution is acceptable.

      community Efficacy of Dut at 0.5mg VS 1mg VS 2.5mg

      in Finasteride/Dutasteride  49 upvotes 1 year ago
      Higher doses of dutasteride, such as 2.5mg, are more effective at reducing scalp DHT than 0.5mg, but are costly and inconvenient. A 1mg dose is considered a more affordable and practical option, though its efficacy is uncertain.

      community What kind of tretinoin should i get?

      in Progress Pictures  1 upvotes 4 months ago
      OP is seeking advice on which percentage of tretinoin to use to enhance the effectiveness of minoxidil for hair loss. They are unsure about choosing between 0.1%, 0.025%, or 0.05% tretinoin.

      community The Cure isn't 5 years away; it's already here.

      in Research/Science  1005 upvotes 1 year ago
      PP405 is a new topical treatment for hair loss, showing promise in trials but still requires finasteride for maintenance. There is skepticism about its effectiveness and safety, with concerns about needing finasteride to maintain results.