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      community How do you guys use minoxidil twice a day?

      in Minoxidil  10 upvotes 1 month ago
      The conversation discusses challenges and tips for applying liquid topical minoxidil twice a day, with users sharing their experiences and methods for managing greasy hair. Many users apply minoxidil once at night, and some combine it with finasteride for better results.

      community 28M 3.5 months great progress and questions

      in Progress Pictures  247 upvotes 4 months ago
      A 28-year-old man is considering whether to proceed with a hair transplant in February or continue using oral minoxidil, finasteride, and dermastamping, which have shown great progress in 3.5 months, to achieve desired results by his wedding in September 2026. Most responses suggest postponing the transplant to avoid potential "shock loss" and relying on the current treatment and hair fibers for the wedding.

      community Reversing 8 years of hair loss. Dut is freaking magic!

      in Progress Pictures  4082 upvotes 1 year ago
      A user successfully reversed hair loss over 17 months using 0.5mg dutasteride and 5mg oral minoxidil daily, noting significant improvement without a transplant. Minor side effects like headaches and testicular discomfort were reported but resolved quickly.

      community Why did you move back to finasteride?

      in Treatment  42 upvotes 1 year ago
      Some users choose finasteride over dutasteride due to fewer side effects and cost, while others find dutasteride more effective despite its side effects. Many combine treatments like minoxidil, finasteride, and dutasteride, adjusting based on personal experiences and side effects.

      community Has Saw Palmetto (or PSO) stopped my shedding?

      in Treatment  5 upvotes 2 years ago
      A user experienced hair shedding despite using natural remedies but saw improvement with topical finasteride and oral minoxidil. After stopping supplements like saw palmetto and pumpkin seed oil, shedding resumed, but combining them again with finasteride and minoxidil reduced shedding.

      community If RU58841 is such an effective anti androgen

      in Research/Science  46 upvotes 2 years ago
      RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.

      community 3 month progress NW5 -- lost cause?

      in Progress Pictures  22 upvotes 3 years ago
      A user is treating their advanced hair loss with a regimen including topical finasteride, minoxidil, hydrocortisone, stem cell serum, peptide serum, multivitamins, he shou wu tea, derma pen, argan oil, and a derma roller. Replies suggest it's too early to judge progress and recommend staying consistent, with one suggesting oral minoxidil as an additional option.

      community 24M seeking help for aggressive androgenetic alopecia - "nuke" stack?

      in Chat  1 upvotes 1 year ago
      A 24-year-old male with aggressive androgenetic alopecia is using 1mg finasteride daily and considering a treatment stack including 0.5mg dutasteride, 2.5mg oral minoxidil, ketoconazole shampoo, Alpecin caffeine shampoo, and RU58841. He seeks advice on the safety and effectiveness of these treatments and whether any adjustments are needed.

      community From Perfect Hair to This: 2 Years of Chronic TE + Unmasked AGA.

      in Treatment  5 upvotes 1 month ago
      A 25-year-old is experiencing chronic telogen effluvium (TE) and androgenetic alopecia (AGA) after surgery, using finasteride, red light therapy, and supplements, and considering oral minoxidil despite heart concerns. They are unsure whether to start minoxidil before or after an upcoming surgery, which may trigger another hair shed.

      community 1 year fin, 5 year min progress

      in Progress Pictures  163 upvotes 1 month ago
      A 23-year-old male saw significant hair improvement after using topical minoxidil for five years and oral finasteride for one year. He is considering adding dutasteride weekly and continues using Head & Shoulders and Stiproxal for dandruff control.

      community Is this the 2026 Hairloss Nuclear Stack?

      in Finasteride/Dutasteride  30 upvotes 2 months ago
      A user discusses their extensive hair loss treatment regimen, which includes dutasteride, oral and topical minoxidil, RU58841, various supplements, and lifestyle changes. The conversation includes opinions on the effectiveness and necessity of such a comprehensive approach, with some users suggesting alternatives like microneedling and questioning the high dosage of dutasteride.

      community Scalp tension/pain = Hair loss?

      in Chat  1 upvotes 3 months ago
      Hair loss was triggered by a testosterone and Masteron cycle, causing scalp tension and shedding. Topical finasteride, RU58841, and oral minoxidil were used to stop shedding and improve scalp condition.

      community Don't think I can go on like this anymore

      in Chat  118 upvotes 6 months ago
      A 24-year-old is struggling with severe depression and anxiety due to hair loss, despite using dutasteride and oral minoxidil for two years. They are advised to consider shaving their head, exploring wigs or hair systems, and focusing on other aspects of life like health, relationships, and career.

      community How far back can Dutasteride regrow losses?

      in Finasteride/Dutasteride  43 upvotes 6 months ago
      Dutasteride can regrow hair lost up to 10 years ago for some, especially when combined with minoxidil, but results vary widely. Some users report significant regrowth, while others see no change or only maintain existing hair.

      community Running Gear- Preemptive Treatment

      in Product 6 months ago
      A 51-year-old on TRT plans to use steroids and is concerned about hair loss, considering topical treatments like Hair Rescue with RU58841 and finasteride, along with Nioxin shampoo. They are cautious about using oral DHT blockers due to potential interactions with steroids like Tren and Anavar.

      community 1 year of 1mg finasteride a day

      in Progress Pictures  305 upvotes 7 months ago
      The user has been taking 1mg of finasteride daily for a year, maintaining hair density without regrowth. They are considering oral minoxidil for regrowth, avoiding topical minoxidil due to its toxicity to cats, despite concerns about heart side effects.

      community Minoxidil is a 5ar inhibitor according to research

      in Research/Science  147 upvotes 7 months ago
      Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

      community 30M, 15 months Dut 0,5 and prp, what now?

      in General  202 upvotes 8 months ago
      A 30-year-old male has been experiencing hair loss despite using Dutasteride 0.5mg and PRP for 15 months, with no success. He is considering a hair transplant but is advised to stabilize hair loss first and explore other treatments like topical Minoxidil or combined therapies.

      community What is the ultimate hair regrowth protocol

      in Treatment  28 upvotes 9 months ago
      The conversation covers aggressive hair regrowth treatments like Dutasteride, Minoxidil (oral and topical), RU58841, microneedling, and ketoconazole shampoo. It also mentions PRP, laser therapy, GHK-Cu injections, and hormone therapy for maximum regrowth.

      community Tretinoin for some men(not all) can cause non-telogen effluvium hair loss

      in Research/Science  4 upvotes 10 months ago
      Tretinoin can cause non-telogen hair loss in some men by inducing catagen-like changes in hair follicles and through retinoid toxicity, especially when used with minoxidil. Some users report hair loss even when using retinoids on the face, while others experience benefits when combined with treatments like finasteride and minoxidil.

      community 24M — 4.5 Months Into Hair Treatment, Feeling Emotionally Drained

      in Is this regrowth?  85 upvotes 1 year ago
      A 24-year-old male is experiencing emotional stress from hair loss despite seeing significant progress after 4.5 months of using oral dutasteride and minoxidil, and has now switched to topical treatments. Many users encourage him to continue with the oral treatments due to his impressive results and suggest waiting at least a year before considering a hair transplant.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 year ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.