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      community Is microneedling really that effective?

      in Microneedling  35 upvotes 9 months ago
      Microneedling's effectiveness for hair growth is debated, with some users reporting positive results when combined with minoxidil and finasteride, while others experienced scarring and no benefits. Needle depth and frequency vary, with some suggesting 0.5-1mm as effective, but caution is advised to avoid overuse and potential harm.

      community KX-826 1% Phase II Results from China Just Dropped

      in Research/Science  37 upvotes 10 months ago
      KX-826 (Pyrilutamide) 0.5% and 1.0% solutions showed promising results in increasing hair count for male androgenetic alopecia, with the 0.5% dose slightly outperforming the 1% dose. The treatment was well-tolerated with no sexual side effects, but skepticism remains due to past inconsistencies in trial results.

      community Just got back fro the hairdresser: what a hell

      in Satire  50 upvotes 11 months ago
      The conversation is about hair loss anxiety and treatments like Minoxidil and finasteride. Users discuss self-acceptance, relationship support, and alternatives like shaving or learning to cut hair at home.

      community PP405 timeframe ? Could it replace current treatments ?

      in Update  34 upvotes 11 months ago
      PP405 is a potential new hair loss treatment that might replace finasteride and minoxidil, but it is still in clinical trials and may not be available until 2028-2031. There is skepticism about its effectiveness, with only a 20% increase in hair density observed in some participants.

      community Exactly one year on Minoxidil and finasteride

      in Treatment  113 upvotes 1 year ago
      The user has been using Minoxidil and finasteride for a year, noticing initial hair regrowth but experiencing shedding recently, causing concern. Suggestions include continuing treatment, considering dutasteride, and checking for other factors like illness or nutrient deficiencies.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

      in Research/Science  114 upvotes 1 year ago
      The conversation discusses the potential of PP405 as a hair loss treatment, with some users expressing skepticism and others hopeful about its development. There is also mention of other treatments like Minoxidil, Finasteride, and Pyrilutamide, with users debating the effectiveness and safety of self-experimentation versus waiting for clinical trial results.

      community When could we expect pp405 to hit the market?

      in Research/Science  31 upvotes 1 year ago
      PP405 is expected to finish Phase 2 trials in late 2025, with potential market availability around 2028-2029 if all goes well. Current treatments like finasteride and minoxidil are still popular, while new options like KX-826 and Breezula are anticipated soon.

      community New warning by FDA on topical finasteride

      in Research/Science  194 upvotes 1 year ago
      The FDA warned that topical finasteride can cause serious side effects like sexual dysfunction and brain fog, similar to oral finasteride. Compounded topical formulations pose additional risks due to lack of regulation.

      community Needling project, I'm needling half of my head

      in Microneedling  1 upvotes 1 year ago
      A person is experimenting with microneedling on one temple while using Minoxidil to address hair loss. They plan to needle weekly and apply Minoxidil twice daily, avoiding application around needling sessions.

      community Totally confused by doctors opinions, would appreciate some clarity

      in Treatment  1 upvotes 1 year ago
      The user is experiencing hair loss and confusion over conflicting medical advice, with treatments including minoxidil, finasteride, and topical corticosteroids. They are unsure about the necessity of a biopsy and the timing of using minoxidil, while also considering the impact of potential androgenetic alopecia and telogen effluvium.

      community My Hair loss/regrowth Journey Since 2017

      in Progress Pictures  9 upvotes 1 year ago
      The user shared their hair regrowth journey since 2017, using treatments like finasteride, minoxidil, dutasteride, RU58841, microneedling, and later feminizing HRT. Significant progress was noted after starting HRT, with continued improvement in hair texture and regrowth.

      community Ru58841 after a hair transplant

      in Transplants  7 upvotes 1 year ago
      A user discussed their hair transplant progress and mentioned using 1mg Finasteride, 5% Topical Minoxidil, and recently starting 5% RU58841. They are seeking advice on whether to use RU58841 at month 4 post-transplant.

      community 9 Month Journey: Massive Second Minoxidil Shed?

      in Minoxidil  43 upvotes 1 year ago
      A 33-year-old man shared his 9-month journey using minoxidil for hair loss, experiencing significant shedding after initial success. He is considering adding finasteride but is hesitant due to trying to conceive.

      community 3 month progress on Minoxidil 5% only.

      in Is this regrowth?  1037 upvotes 2 years ago
      A user is pleased with their hair regrowth after 3 months using Minoxidil 5%. They plan to start Finasteride upon returning home, and others discuss the importance of consistency and patience with hair loss treatments.

      community Why are more people not using RU58841

      in Product  14 upvotes 2 years ago
      People are not using RU58841 for hair loss because it's not FDA approved, lacks long-term safety data, and is difficult to obtain and verify. They prefer FDA-approved treatments like minoxidil, finasteride, ketoconazole shampoo, and microneedling.

      community Herbacle hair growth serum with 0% min

      in Product  20 upvotes 2 years ago
      The conversation discusses the effectiveness of a new hair growth serum called HERBACLE, which claims to be the world's first, but lacks reviews and is doubted by users. One user notes that its ingredients are similar to those in The Ordinary's Multi-Peptide Serum for Hair Density.

      community Rare Non responder to Finasteride, Dutasteride, and oral minoxidil

      in Minoxidil  78 upvotes 2 years ago
      A user did not respond to finasteride, dutasteride, and oral minoxidil for hair loss after four years of treatment and is considering scalp micropigmentation (SMP). Other users suggest the hair loss pattern may indicate alopecia areata and recommend seeing a dermatologist.

      community My barber noticed my progress 😁

      in Update  207 upvotes 2 years ago
      A user's barber noticed significant improvement in their hair thickness after they started using 2.5mg Minoxidil since August 2023 and 1mg Finasteride daily since September 2023. The user has experienced some headaches when missing Minoxidil doses but has not noticed major side effects.

      community I have started taking creatine supplement

      in Product  17 upvotes 2 years ago
      The conversation discusses the potential impact of creatine on hair loss, with some users reporting no effect and others experiencing increased hair shedding. The original poster is using finasteride, minoxidil, and a derma pen, and has started taking creatine to observe any changes in hair loss.