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      community Homemade topical dutasteride/finasteride

      in Finasteride/Dutasteride  4 upvotes 4 months ago
      The conversation discusses making homemade topical solutions of dutasteride or finasteride using tablets, with suggestions to use alternatives like MinoxidilMax or stemoxydine due to difficulties in formulation. Some users recommend sticking to oral pills for effectiveness and ease.

      community Has anyone tried/made a sulforaphane topical?

      in Treatment  4 upvotes 3 years ago
      The conversation discusses the potential of creating a homemade sulforaphane topical for hair loss treatment. Participants mention challenges with sulforaphane stability and reference other treatments like Minoxidil.

      community Caffeine + Dimethylglycine (DMG) Shampoo research

      in Research/Science  6 upvotes 1 year ago
      A user discusses the potential of caffeine and DMG in shampoo for treating hair loss, citing a pending patent and personal plans to test it. They find it more convenient than using minoxidil, tretinoin, and microneedling.

      community Anyone hear of Ursolic Acid?

      in Question  3 upvotes 6 years ago
      Ursolic acid, found in apple peels, lemongrass, rosemary, and lavender, may have anti-androgen effects similar to finasteride. It might be beneficial for hair health when used with other treatments like Minoxidil, Finasteride, and RU58841.

      community RU58841 is the only thing that worked for me, a DUPA sufferer

      in Treatment  1 upvotes 9 months ago
      RU58841 was the only treatment that slowed hair loss and reduced irritation for a DUPA sufferer after trying finasteride, minoxidil, and dutasteride with no success. The user continues using 6mg oral minoxidil, 0.5mg dutasteride, and an 8% RU58841 solution.

      community Interested about what other adjunct therapies people are trying & whats working?

      in Treatment  7 upvotes 2 years ago
      The conversation discusses alternative hair loss treatments beyond the commonly used Minoxidil and Finasteride. One user is trying diclofenac gel, caffeine + antioxidant serum, finasteride, ketoconazole shampoo, and has stopped using Minoxidil due to ineffectiveness, while another user has adopted lifestyle changes like exercise, diet, stress reduction, and topical caffeine, along with scalp massages and microneedling.

      community Chinese Research Chemicals You Suggest

      in Research/Science  3 upvotes 8 months ago
      The conversation discusses hair loss treatments, specifically RU58841, with mentions of side effects from finasteride and dutasteride. Alternatives like Pyri, KX-826, and Breezula are also mentioned.

      community Pyrilutamide for non-5AR users?

      in Treatment  10 upvotes 1 year ago
      Pyrilutamide is considered by some as an alternative for those avoiding 5AR inhibitors like finasteride and dutasteride, but opinions on its effectiveness vary. Some users report similar results with fluridil and pyrilutamide, while others find pyrilutamide less effective compared to prescription treatments.

      community found out im more responsive to dutastetide than finasteride

      in Finasteride/Dutasteride  18 upvotes 3 years ago
      The user switched from finasteride to dutasteride for hair loss and saw significant improvement in under two months. They also microneedle, take supplements including collagen and vitamin D3, use ketoconazole shampoo, and noticed accidental hair regrowth with retinol application on their face.

      community Rosemary oil's potency as a dht blocker

      in Research/Science  65 upvotes 2 years ago
      Rosemary extract showed high inhibitory activity against DHT, similar to finasteride and dutasteride, but the conversation includes skepticism about its effectiveness in humans since the study was done on mice and rosemary oil is often considered ineffective based on personal experiences. Some suggest trying rosemary oil alongside other treatments, while others emphasize the difference between the extract used in the study and the oil.

      community Patent for topical resveratrol and melatonin for AGA

       5 upvotes 6 years ago
      The conversation discusses a patent for using topical resveratrol and melatonin to treat androgenetic alopecia (AGA) and also mentions interest in topical sulforaphane as a treatment.

      community DIY Minoxidil mix with Fin, Caffeine, Cetirizine, and Melatonin?

      in Treatment  4 upvotes 10 months ago
      A user plans to create a custom topical solution by adding finasteride, caffeine, cetirizine, and melatonin to a minoxidil bottle, questioning the stability and effectiveness of this mix. Concerns include potential crystallization and solution muddiness with added ingredients.

      community Kintor Pharma Announces Positive Top-line U.S. Phase I Trial Results of GT20029, the World’s First Topical Use PROTAC Compound

      in Research/Science  127 upvotes 3 years ago
      The conversation discusses positive initial trial results for GT20029, a topical compound for hair loss that degrades androgen receptors, potentially requiring only weekly application. Participants express hope for this treatment to be more effective and convenient than current options like Minoxidil, Finasteride, and RU58841.

      community Compounding for topical formulations?

      in Treatment  1 upvotes 2 years ago
      The post discusses the high cost of a topical hair loss treatment from Happy Head, which contains finasteride, minoxidil, retinoic acid, and hydrocortisone. The user is seeking cheaper alternatives, specifically asking if there are compounding pharmacies that can recreate the same or similar formulation.

      community Natural DHT Blockers instead of fin

      in Finasteride/Dutasteride  4 upvotes 5 years ago
      The conversation discusses using natural DHT blockers like saw palmetto, beta sitosterol, pumpkin seed oil, pygeum africanum bark, and nettle root as alternatives to finasteride for hair loss, with mixed opinions on their effectiveness. Some users report minimal improvement with natural options and better results with finasteride or dutasteride, despite concerns about potential side effects.

      community Has anyone tried those aliexp product ?

      in Product 1 month ago
      The conversation is about exploring additional hair loss treatments, with suggestions including topical melatonin, caffeine-based shampoos, redensyl, copper-peptides, pumpkin seed oil, saw palmetto, ketoconazole shampoo, and fluridil. Caution is advised against using products from AliExpress and Temu due to potential safety concerns.

      community Trichosol, polyethylene glycol, and DMSO

      in Minoxidil  3 upvotes 1 year ago
      The user experiences irritation from alcohols in minoxidil and is considering alternatives like trichosol mixed with polyethylene glycol or DMSO. They seek advice on the best nonirritating option.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 year ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community Has anyone tried CB-01-03 aka Clascoterone?

      in Research/Science  2 upvotes 1 month ago
      Clascoterone, a topical anti-androgen, is generating interest for potentially fewer systemic side effects. Users are curious about its effectiveness and details like concentration and duration of use.