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      community Switch to generic meds?

      in General  34 upvotes 2 days ago
      The user is considering switching from Hims to generic minoxidil and finasteride, with slightly lower dosages. They are concerned about maintaining their current hair condition without regrowth.

      community A small tip for diffuse thinners

      in Product  9 upvotes 3 years ago
      A user with diffuse thinning shares a tip for improving hair appearance by using a shea butter and coconut oil serum from Trader Joe's at night. They are on finasteride and considering adding minoxidil for better results.

      community Petition Alert: Let's Get PP405 Phase 3 Trials in Germany by 2026!

      in Research/Science  58 upvotes 9 months ago
      A user is advocating for Phase 3 trials of the hair loss treatment PP405 to be conducted in Germany, citing benefits like a diverse patient base and faster access for European patients. Despite skepticism about the petition's influence, the user believes it can demonstrate significant interest and potentially influence strategic decisions.

      community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

      in Research/Science  215 upvotes 1 year ago
      PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

      community Treating MPB while dealing with seborrheic dermatitis?

      in Treatment  8 upvotes 1 year ago
      The user is seeking advice on treating male pattern baldness (MPB) while dealing with seborrheic dermatitis, specifically asking about the use of finasteride (Fin) and minoxidil (Min). They are concerned about side effects and are looking for recommendations to improve overall hair thickness, especially on the crown.

      community Ru58841 for a female w male pattern baldness

      in General  166 upvotes 1 year ago
      A user is considering using RU58841 for female pattern baldness and is also planning to use Minoxidil. They are hesitant to ask their doctor for spironolactone due to its cosmetic nature and are experiencing significant hair loss possibly due to stress and hormonal issues.

      community Rate my treatment stack from 1-10

      in Chat 1 year ago
      The conversation discusses various hair loss treatments, with a focus on pyrilutamide, minoxidil, and alternatives to finasteride due to intolerance. Users suggest adding a DHT blocker like finasteride or dutasteride, and some recommend trying topical versions to reduce side effects.

      community Regimen proposal (incl. dut meso) (event industry)

      in Finasteride/Dutasteride  1 upvotes 8 months ago
      A user in their early 20s is concerned about minor hair thinning and is considering a hair loss regimen involving PRP sessions, mesotherapy with dutasteride injections, and low-dose finasteride. They dislike minoxidil due to its greasiness and prefer a routine that is easy to maintain.

      community Breezula phase 3 results said to be released next month

      in Product  28 upvotes 1 year ago
      Breezula's phase 3 results are expected soon, with discussions on the effectiveness of androgen receptor antagonists like spironolactone and the potential of GT20029. Users express skepticism about new treatments and discuss the complexities of male pattern baldness, often relying on finasteride despite its side effects.

      community Studies show: 0.2 mg reduces scalp DHT by ~55%. 1 mg reduces it by ~64%. 5 mg reduces it by ~69%.

      in Finasteride/Dutasteride  148 upvotes 6 months ago
      Finasteride reduces scalp DHT significantly even at low doses, with 0.2 mg reducing it by about 55%, but higher doses like 1 mg and 5 mg offer only marginally more reduction. Users discuss side effects, with some experiencing none and others reporting issues like low libido, and they also mention using other treatments like minoxidil and dutasteride.

      community Can trichodynia ruin an exosome treatment?

      in Chat  1 upvotes 1 year ago
      The user has tried various hair loss treatments including topical minoxidil, oral finasteride, oral dutasteride, oral minoxidil, and exosome therapy, but none have been effective. They suspect trichodynia might be preventing these treatments from working.

      community Switching from fin 1mg to dut 0.5mg after 13 years

      in Treatments  101 upvotes 11 months ago
      The user has been using Finasteride 1mg daily for 13 years with stable results but is now experiencing thinning hair and is considering switching to Dutasteride 0.5mg. They are seeking advice on whether this change might be beneficial.

      community Oral min vs topical comparison

      in Treatment  10 upvotes 1 year ago
      Oral minoxidil is claimed to be more effective and easier to use than topical minoxidil, with a 100% response rate, but it may cause unwanted body hair growth and has potential heart-related side effects. Topical minoxidil is less effective for many due to enzyme limitations, can cause scalp issues, and is more challenging to apply, but it avoids systemic side effects.

      community Shedding about 4 years, now smth between NW3-4. Believed reasin was my low ferretin, but still has hairlost. Dht level is 425. Could it be dht that is the reason?

      in Chat  3 upvotes 1 year ago
      Loose-Message9596 has been experiencing hair loss for 3-4 years, initially due to low ferritin and vitamin D levels, and has tried treatments like vitamins, System 4, and PRP therapy. They are considering starting finasteride and minoxidil but are unsure due to their relatively low DHT level of 425.
      I have diffused thinning. Is it over for me? 20 year old

      community I have diffused thinning. Is it over for me? 20 year old

      in General  262 upvotes 2 days ago
      A 20-year-old with diffused thinning is using oral minoxidil for androgenetic alopecia. They plan to switch to topical minoxidil, finasteride, and bimatoprost, and may consider surgery if their condition improves.

      community literally dht beef bruhhsmhmmhh😡😡😡😡😡😤

      in Finasteride/Dutasteride  128 upvotes 10 months ago
      The conversation discusses using finasteride, dutasteride, RU58841, and testosterone to combat hair loss and block DHT, with some users expressing concerns about side effects and vegan options for medication. The discussion also touches on personal experiences with hormone treatments and the desire to maintain a youthful appearance.

      community Pre Finasteride Treatment, is testing for free DHT necessary?

      in Finasteride/Dutasteride  5 upvotes 3 years ago
      The conversation is about whether testing for free DHT is necessary before starting Finasteride for hair loss, despite having other hormone tests available. One person suggests that genetic response to DHT is more important than DHT levels and advises starting Finasteride without the free DHT test.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Making your own RT1640 in China

      in Research/Science 4 years ago
      RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.