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      community Pyrilutamide vs topical finasteride

      in Finasteride/Dutasteride  2 upvotes 11 months ago
      The user is considering switching to topical finasteride or pyrilutamide to stabilize hair loss before a hair transplant, currently using oral minoxidil and finasteride. Suggestions include sticking to the current regimen as it is already potent, and caution against using pyrilutamide from unreliable sources.

      community Additional supplements / peptides to maximize finasteride benefit

      in Research/Science  3 upvotes 2 weeks ago
      The user is using finasteride, HGH, GHK-CU, BPC-157, KPV, biotin/collagen/keratin vitamins, ketoconazole shampoo, and low-dose naltrexone to address hair loss, avoiding minoxidil due to past shedding experiences. Adenosine is discussed as a potential alternative to minoxidil, though it is noted to be expensive and hard to find.

      community Do not use oral dutasteride from Strut Health.

      in Finasteride/Dutasteride  29 upvotes 3 years ago
      The ineffectiveness of Strut Health's dutasteride capsules, which are filled with raw powder instead of liquid and don't contain any buffering agents that would allow for absorption into the bloodstream. It is suggested to use other brands of liquid-filled dutasteride capsules for better results.

      community I think Ru58841 stopped my itching.

      in Chat  4 upvotes 1 year ago
      RU58841 stopped scalp itching for the user, providing relief from persistent itchiness associated with hair loss. Some users reported side effects like chest pain, while others found relief with different treatments like mometasone.

      community topical fluridil/eucapil + dut to block all DHT+T from scalp?

      in Treatment  8 upvotes 4 years ago
      User experienced slow gains with topical fin+min, switched to topical dut+min, and considered adding Eucapil. Another user suggested DUT may be less effective topically due to high molar mass and mentioned Fluridil as a weak anti-androgen that could help.

      community Pyrilutamide is literally my only hope

      in Chat  91 upvotes 3 years ago
      Considering treatments for hair loss, including Minoxidil, Finasteride, RU58841, Fluridil and Pyrilutamide. The user is weighing the risks of taking unapproved medication before it has been mass produced.

      community I think microneedling before topical application of finasteride (or dut) is a path we should investigate (for those of us who don't care about systemic absorption). Here's why...

      in Microneedling  20 upvotes 9 months ago
      Microneedling before applying topical finasteride or dutasteride may enhance their effectiveness by increasing local absorption in the scalp, despite concerns about systemic absorption. Users discuss combining this method with oral treatments and minoxidil, noting potential benefits and side effects.

      community 5 months oral 1.2mg Fin, 3mg Min. Switching to Dut. 39M

      in Progress Pictures  17 upvotes 5 months ago
      The user has been using oral finasteride and minoxidil for five months with some progress and plans to switch to dutasteride, while also considering a hair transplant for better coverage. Suggestions include adding microneedling, Nizoral shampoo, and possibly using both oral and topical treatments for improved results.

      community buzzcut did wonders for my trim (21m on fin/min)

      in Update  7 upvotes 10 months ago
      A user experienced reduced stress and improved hair appearance after getting a buzzcut while using finasteride, minoxidil, and microneedling. The user feels the haircut and treatments may have improved hair quality and filled in patchy areas.

      community P-1075: a BETTER version of Minoxidil

      in Research/Science 7 months ago
      P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

      community How much DHT causes hair loss ?

      in Finasteride/Dutasteride  2 upvotes 7 months ago
      The user is taking 2.5 mg dutasteride and 5% minoxidil but is not seeing hair regrowth, and is considering adding RU58841. They are experiencing fatigue and low MCV/MCH, possibly related to dutasteride, and are advised to be patient, consider microneedling, and check for iron deficiency.

      community IT ACTUALLY WORKED - 9 month Dut + Min update

      in Progress Pictures  441 upvotes 4 months ago
      A user shared successful hair regrowth results after 9 months using 0.5mg Dutasteride and 2.5mg Minoxidil daily, with no side effects. The user chose Dutasteride over Finasteride for its potency and perceived lower side effects.

      community Trestolone (MENT) as a nuclear treatment

      in Treatment  99 upvotes 3 years ago
      Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

      community RU-58841 without finassteride?

      in Treatment  6 upvotes 11 months ago
      RU58841 is used without finasteride by some due to side effects, with mixed results. Users report combining RU58841 with minoxidil and adjusting finasteride doses to manage hair loss.

      community Efficacy and Systemic DHT Suppression of Topical Finasteride vs Dutasteride

      in General  122 upvotes 1 year ago
      Topical dutasteride may have limited absorption due to its higher molecular mass compared to finasteride, potentially affecting its efficacy in suppressing DHT locally. Microneedling might enhance dutasteride absorption, possibly offering stronger local DHT suppression with fewer systemic effects.

      community Dutasteride only might be the best ROI

      in Finasteride/Dutasteride  176 upvotes 3 months ago
      Switching from finasteride to dutasteride can improve hair regrowth with fewer side effects for some users. Concerns about shedding, lack of improvement, and the long-term safety of oral minoxidil remain.

      community Stemoxydin and hair cycle question

      in Treatment  2 upvotes 2 years ago
      The user has been using Finasteride for hair loss and is considering adding alphatradiol, stemoxydine, or 2% minoxidil to their regimen. They are concerned that stemoxydine, which shortens the resting phase of hair, might accelerate hair loss in those not using Finasteride by depleting hair cycles without strengthening miniaturized hairs.