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      community Update on PP405 Trails - Pelage

      in Research/Science  14 upvotes 4 months ago
      The conversation discusses interest in participating in PP405 trials for hair loss treatment, with users expressing uncertainty about eligibility due to location. Participants are eager for updates and willing to pay for shipping if trials are limited to America.

      community Being non responsive on dut and min

      in Is this regrowth?  6 upvotes 2 months ago
      The user is experiencing hair loss despite using dutasteride, minoxidil, and ketoconazole shampoo, and is concerned about continued shedding. Suggestions include checking for nutrient deficiencies, consulting a dermatologist, and considering other potential causes like seborrheic dermatitis or telogen effluvium.

      community I got my bloodwork done... What now?

      in Update  6 upvotes 5 months ago
      The user has been experiencing hair thinning despite taking finasteride and minoxidil for six months. Bloodwork suggests a vitamin D deficiency, and users recommend consulting a doctor and possibly supplementing vitamin D.

      community The MPB itch aka DHT itch is very real.

      in Chat  9 upvotes 3 years ago
      Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

      community Dut only 0.5 mg, age 30 to 32,

      in Progress Pictures  106 upvotes 11 months ago
      A user shared their experience using dutasteride for hair loss, noting subtle improvements and thicker hair without significant regrowth. They did not use finasteride or minoxidil, and experienced occasional shedding but no side effects.

      community Can fin changing dosage frequency cause shedding?

      in Finasteride/Dutasteride  2 upvotes 1 year ago
      The user reduced their finasteride dosage and added vitamin D due to deficiency, questioning if this change could cause hair shedding. Another user suggests shedding is unlikely with this dosage change, but more likely with a stronger drug like dutasteride.

      community 16, female, losing a ton of hair

      in Female  7 upvotes 2 years ago
      A 16-year-old female experiencing severe hair loss and sebum buildup, likely due to telogen effluvium and PCOS, is currently using vitamin D3 supplements, Redenser serum, and T follihair supplements. Recommendations include addressing PCOS first and consulting a doctor.

      community PP405 mechanism question - looking for discussion

      in Treatment  6 upvotes 2 months ago
      PP405 may promote short-term hair growth by pushing follicles into the growth phase, but concerns exist about long-term effects due to lack of rest phases. Users discuss various treatments like finasteride, minoxidil, spironolactone, alfatradiol, and investigational drugs like KX-826 and GT20029 for hair maintenance and regrowth.

      community Anger and frustration as I finally learn my diagnosis.

      in Female  6 upvotes 2 years ago
      A young female diagnosed with Lichen planopilaris (LPP) experienced years of misdiagnosis and ineffective treatments, including a hair transplant and other procedures. She is considering litigation due to the misdiagnosis and has learned that LPP is chronic, hair loss can be stopped with ongoing medication, but lost hair cannot regrow.

      community If PP405 works it will be fkn impossible to buy it.

      in Technology  102 upvotes 7 months ago
      PP405 is a potential hair loss treatment that may activate dormant hair follicles, but there are concerns about its effectiveness, cost, and side effects. Users discuss treatments like minoxidil, finasteride, and RU58841, expressing skepticism about PP405's long-term success and accessibility.

      community finasteride not working help !

      in Finasteride/Dutasteride 2 years ago
      A user is experiencing worsening hair loss despite using finasteride, PRP treatments, and supplements like vitamin D, biotin, zinc, and iron. They are seeking advice on whether to continue with finasteride, increase the dosage, or try additional PRP sessions.

      community Should I switch from fin to dut? (21 y/o diffuse thinner)

      in General  134 upvotes 6 months ago
      A 21-year-old experiencing diffuse thinning is considering switching from finasteride to dutasteride after using topical and oral minoxidil and finasteride. They have seen some regrowth but are concerned about overall density loss, especially at the crown.

      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 4 months ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

      community pyrilutamide solution progress log

      in Product  20 upvotes 3 years ago
      A 28 year old using a hair loss prevention protocol to restore thinning hair, which includes finasteride, dutasteride, minoxidil, stemoxydine, alopecin, nizoral shampoo and microneedling; the user is now adding pyrilutamide solution to the regimen with the hope of improving their results. RU58841 was also ordered but not yet used.

      community PP405 timeframe ? Could it replace current treatments ?

      in Update  34 upvotes 11 months ago
      PP405 is a potential new hair loss treatment that might replace finasteride and minoxidil, but it is still in clinical trials and may not be available until 2028-2031. There is skepticism about its effectiveness, with only a 20% increase in hair density observed in some participants.