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community ASC-J9: Poor man’s GT-20029 that might work for regrowth. Anyone try this stuff?

in Research/Science 3 years ago

The potential hair regrowth benefits of ASC-J9, a synthetic modified version of curcumin that is said to be more effective than Minoxidil and Finasteride. Reports from users suggest good thickening and temple regrowth with topical use at 0.025% concentration.

community I ingested RU58841 orally to see if its legit

in Chat 133 upvotes 11 months ago

A user ingested RU58841 orally and experienced severe heart and breathing issues, requiring emergency medical assistance. They concluded that MV supplements is a legitimate supplier but warned of the serious side effects.

community Struggling to see progress dutasteride mesotherapy and minoxydil

in Is this regrowth? 2 upvotes 3 weeks ago

The user is experiencing hair thinning and has been using minoxidil, dutasteride mesotherapy, and red light therapy for 4.5 months without seeing results. They are considering changing their treatment due to lack of progress.

community Kintor Pharmaceutical Announces AR-PROTAC (GT20029) Approved for Acne and Androgenic Alopecia Clinical Trials in China

in Technology 13 upvotes 5 years ago

The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

community Apparently azelaic acid inhibits DHT, what are the side effects?

in Research/Science 4 upvotes 5 years ago

Azelaic acid is discussed as a DHT inhibitor with no reported sexual side effects, but its effectiveness and absorption as a topical treatment are questioned. The user is interested in azelaic acid due to concerns about finasteride affecting penile health.

community Realistically, how much PP405 will cost?

in Treatment 27 upvotes 1 year ago

PP405 is in phase 2 trials for hair loss, with discussions on its cost and effectiveness compared to minoxidil and finasteride. Users are skeptical about its efficacy and timeline, with hopes for market release by 2027.

community Any other treatments to still be hopeful for?

in Research/Science 20 upvotes 2 years ago

The conversation discusses the potential of new hair loss treatments, with a focus on pyrilutamide, gt20029, and topical alfatradiol, and the possibility of improving their effectiveness through methods like increased concentration and microneedling. Dutasteride is also mentioned as a stronger option.

community Why can't you drink caffeine after PRP?

in Treatment 11 upvotes 4 years ago

The conversation discusses avoiding caffeine after Platelet-Rich Plasma (PRP) treatment for hair loss because caffeine is a vasoconstrictor, which can reduce blood flow and hinder the healing process that PRP aims to promote.

community Puffy cheeks from lack of dht? Water retention? Estrogen?

in General 55 upvotes 5 months ago

Stopping finasteride may reduce water retention or alter fat distribution, leading to a leaner face. Hormonal changes, like reduced DHT or increased estrogen, could cause these effects.

community Galenic lotion. Science behind the components

in Treatment 1 upvotes 9 months ago

A user is considering a hair loss treatment lotion containing minoxidil, adenosine, caffeine, melatonin, and azelaic acid, questioning the interaction between caffeine and adenosine receptors. Another user suggests adding a topical anti-DHT ingredient like spironolactone, noting it should not be taken orally by men.

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