The conversation discusses the storage and use of pyrilutamide for hair loss, where one user advises against keeping it in the freezer as it may crystallize the active compounds.
A user experienced facial swelling while taking spironolactone for androgenic alopecia, despite its diuretic properties. They are unsure about increasing the dose due to this side effect.
The user switched from finasteride to dutasteride due to side effects and is experiencing fewer side effects with dutasteride, though some scalp itching has occurred. Blood tests show elevated testosterone and estrogen, low DHT, and normal liver and cholesterol levels, leading the user to feel confident in the long-term benefits of dutasteride for hair regrowth.
Users discuss their experiences with finasteride, expressing regret over delayed use due to misinformation and sharing mixed outcomes, including side effects and benefits. Treatments mentioned include finasteride, dutasteride, and minoxidil.
The user experienced headaches and brain fog with a topical solution containing Dutasteride, Minoxidil, Tretinoin, Fluocinolone, Latanoprost, and Caffeine. They are considering switching to oral or topical Finasteride to see if it alleviates these side effects.
User noticed beard and sideburn hair loss, and thinning eyebrows, diagnosed with alopecia barbae and male pattern baldness, and prescribed Desonide cream. User seeks feedback on Desonide cream.
Folligenz liposomal minoxidil sulfate is being discussed for its effectiveness and cost, with users comparing it to regular minoxidil and tretinoin. One user found no difference with the 10% version and noted that a lower tretinoin percentage reduced side effects like skin peeling.
A user humorously complains about not seeing immediate hair growth results after one day of using finasteride and minoxidil, even after microneedling. Replies include jokes and exaggerated experiences, with one user suggesting a satirical method of mixing and freezing the treatments.
The user is experiencing severe hair loss, possibly due to telogen effluvium, after stress, poor nutrition, and hormonal changes. They are using Nizoral and supplements but are considering hormonal treatments like spironolactone despite previous side effects.
The user recovered from Post-Finasteride Syndrome (PFS) using a specific hormone protocol after trying finasteride and dutasteride. They now help others with PFS by reviewing blood work and offering personalized advice.
The Phase 2 trial for Pyrilutamide in the US, which started a year after the China trials, and inquiring about any available information on when it will finish. Treatments discussed include Minoxidil, Finasteride, and RU58841.
Setipiprant trial for hair loss failed, showing no difference between placebo and treatment. Discussion also noted placebo users reporting side effects.
Topical minoxidil with tretinoin is causing redness, stinging, and flaking on the scalp. Reducing application frequency and using anti-dandruff shampoo may help alleviate symptoms over time.
The user is experiencing potential side effects from a 3-in-1 pill containing Finasteride, Minoxidil, and Biotin, including dizziness, blurry vision, and reduced libido. They are considering tapering off the medication as advised by their dermatologist to see if symptoms improve.
The user experienced tiny vellus hairs from 0.5mg finasteride and 2.5mg minoxidil over 9 months. Topical minoxidil, alfatradiol, and RU58841 applied twice daily for 1.5 months significantly improved temple hair regrowth.
The conversation discusses the impact of finasteride on sexual function, with many users reporting reduced libido and weaker erections despite continuing the treatment to prevent hair loss. Some users suggest checking hormone levels or switching to different dosages or treatments like dutasteride, while others share mixed experiences regarding the severity of side effects.
The user used finasteride but stopped due to side effects, then used topical minoxidil for 13 months, and later added KX826/pyrilutamide for 8 months. They experienced shedding after starting pyrilutamide and use minoxidil and KX826 once daily.
The user shared their 5-month hair progress using oral finasteride and minoxidil, reporting positive results with minimal side effects. They use a chewable 2-in-1 product from Hims for convenience.
A 35-year-old male experiences rapid hair loss on his head and body despite normal test results for testosterone, thyroid, and vitamins. He previously used topical minoxidil and retinol, and doctors have been consulted without finding a clear cause.
The user reports significant hair density improvement after 8.5 months of using finasteride, with no side effects except for initially watery semen. They also mention increased sex drive, which they attribute to finasteride, and regret not starting the treatment earlier due to fear of side effects.
The conversation discusses the need for a localized 5-alpha reductase inhibitor that only affects the scalp without systemic side effects, similar to pyrilutamide's approach. Current treatments like topical liposomal finasteride and dutasteride are mentioned, but concerns about their systemic effects and lack of research are highlighted.
KX-826 Pyrilutamide 1% is launching soon, and users are discussing its potential benefits and drawbacks compared to other treatments like Minoxidil and finasteride. Some users are skeptical about its effectiveness, while others are hopeful it will be a safer alternative.
The user experienced significant hair regrowth and increased density after six months of using oral minoxidil and finasteride chewables, despite going through a secondary shedding phase. The only side effect mentioned was restlessness, and the user feels healthier overall.
The conversation discusses the effectiveness of RU58841 for hair loss compared to pyrilutamide, which failed to show significant hair regrowth in trials. Some users report personal side effects with RU58841 and question the criteria for success in hair loss treatments.
Pyrilutamide's systemic degradation is unclear, unlike fluridil, which becomes inactive in the body. The discussion focuses on whether pyrilutamide shares this property.
A user experienced severe sexual side effects and man boobs after 11 months of finasteride use, despite initial positive results for hair growth. They are discontinuing finasteride and caution others about potential risks, suggesting that side effects may be more common than reported.
A female in her late 30s experienced hair thinning due to health issues and treatments, including antibiotics and stress. She started using minoxidil, biotin, and vitamins from **hers** and is currently dealing with shedding and possible weight gain.
A user shared positive results from using 0.5 mg finasteride daily for 3.5 months, noting no side effects and visible hair regrowth. Others commented on their experiences, with some expressing hope and others cautioning about potential side effects.
RU58841 alone had mixed results; some users combined it with minoxidil. One user experienced side effects with finasteride and maintained with RU58841 and minoxidil, but noted possible chest pain.