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GlossaryFludarabine

chemotherapy drug treating chronic lymphocytic leukemia by inhibiting DNA synthesis

Fludarabine, also known as Fludara, is a chemotherapy medication used primarily to treat chronic lymphocytic leukemia (CLL). It works by interfering with the DNA synthesis of cancer cells, thereby inhibiting their growth and proliferation.

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community 0.25 alfatradiol or 0.5 Pyrulitamide ?

in Product 4 upvotes 8 months ago

The conversation is about choosing an anti-androgen for hair loss treatment, with options being alfatradiol and pyrilutamide. Alfatradiol is considered a better choice due to its established use, while pyrilutamide is more experimental.

community Why was fluridil abandoned and never made past phase 2?

in Chat 4 upvotes 4 years ago

Fluridil was abandoned due to its weak effectiveness and low binding affinity to the androgen receptor, making it less competitive against DHT and testosterone. Users discuss its limited results compared to other treatments like pyrilutamide and RU58841.

community Pyrilutamide available at Actifolic now

in Research/Science 15 upvotes 3 years ago

Pyrilutamide, a new hair loss product with the potential to be more effective than RU58841 and safer than CB, but expensive.

community No sides with Ru58841 mixed with stemoxydine, yet sides mixed with fluridil

in Treatment 6 upvotes 3 years ago

User mixed RU58841 with stemoxydine, experienced no side effects. Mixing RU58841 with fluridil caused chest tightness.

community Can I mix the Premixed RU58841 Solution into Alfatradiol?

in Treatment 5 upvotes 2 years ago

The user wants to mix 0.2 ml of RU58841 solution with 2 ml of Alfatradiol to use 10 mg of RU58841 daily due to concerns about side effects. They are asking if this combination would be effective for hair loss treatment.

community Just started my first vial of fluridil

in Treatment 4 upvotes 2 years ago

Fluridil was discussed as a hair loss treatment, with some users experiencing side effects like lethargy and chest tightness. Users also mentioned other treatments like RU58841 and finasteride, with mixed opinions on their effectiveness.

community Alfatradiol 0.1% anyone know a source?

in Treatment 3 upvotes 1 year ago

The conversation is about finding a source for Alfatradiol 0.1% as most available products are 0.025%. A suggestion was made to use four times the dosage of the 0.025% product.

community Fluridil status in 2022: User experiences and higher concentrations

in Research/Science 6 upvotes 3 years ago

Fluridil's effectiveness and safety in treating hair loss are discussed, with higher concentrations showing potential success. Comparisons are made to other treatments like RU58841, Pyri, CB-03-01, and topical spironalactone.

community Pyrilutamide Phase 3 on its way

in Treatment 128 upvotes 4 years ago

Pyrilutamide Phase 3 approved, starting early 2022 with 416 subjects for 24 weeks. Drug potentially better than RU and Breezula, with some users reporting no side effects.

community Fluridil/Eucapil UAE customs regulation

in Chat 1 year ago

A user in the UAE is facing customs issues with ordering Fluridil (Eucapil) and is considering ordering smaller quantities or switching to Pyrilutamide. They are also using finasteride daily to maintain hair and are unsure of Fluridil's effectiveness.

community Pyrilutamide and RU alternatives?

in Treatment 1 upvotes 1 year ago

Pyrilutamide is officially available for purchase, and users suggest Fluridil as an alternative topical anti-androgen. Some users report positive results with pyrilutamide from Koshine.

community Using Pyrilutamide next to RU58841 good? Pyri stronger than Fluridil?

in Treatment 3 upvotes 2 years ago

The user plans to use RU58841 in the morning and Pyrilutamide in the evening for hair loss treatment, considering replacing Fluridil with Pyrilutamide. They believe Pyrilutamide is effective.

community Pyrilutamide +Alfatradiol 0.1% , no Hairloss anymore

in Treatment 43 upvotes 1 year ago

OP experienced diffuse thinning for 11 years and used Minoxidil and Finasteride previously. They now use Pyrilutamide 0.5% and Alfatradiol 0.1%, resulting in significantly reduced hair loss.

community "Fluridil - As Good As RU58841 Without The Side Effects!?" ------ anyone here on fluridil?

in Technology 21 upvotes 5 years ago

Treatments for hair loss, such as Minoxidil, finasteride, RU58841 and Eucapil; the legitimacy of RU58841 products; and safety concerns related to using RU58841.

community Should I consider switching from Fluridil to Pyrilutmide?

in Treatment 12 upvotes 1 year ago

The conversation is about considering switching from Fluridil to Pyrilutamide for hair loss treatment. Pyrilutamide is suggested to be more effective, with a recommendation to use the 1% variant twice daily.

community Best carrier for pyrilutamide?

in Update 9 upvotes 3 years ago

The conversation is about adding a low dose of pyrilutamide to a hair loss treatment regimen. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

community Would Fluridil and Alfatradiol work effectively in conjunction with each other?

in Treatment 6 upvotes 6 years ago

Whether using both Fluridil and Alfatradiol together could be more effective than either one alone as a hair loss treatment, given their different mechanisms of action.

community Got sides on fin, now Alfatradiol or Fluridil?

in Finasteride/Dutasteride 4 upvotes 4 years ago

The user experienced side effects from finasteride and is considering adding Alfatradiol or Fluridil to their regimen, which includes Minoxidil, dermarolling, and ketoconazole. Fluridil is noted to be more effective than Alfatradiol but less effective than finasteride, with mild side effects reported.

community pyrilutamide solution progress log

in Product 20 upvotes 3 years ago

A 28 year old using a hair loss prevention protocol to restore thinning hair, which includes finasteride, dutasteride, minoxidil, stemoxydine, alopecin, nizoral shampoo and microneedling; the user is now adding pyrilutamide solution to the regimen with the hope of improving their results. RU58841 was also ordered but not yet used.

community Is anoying mixing pyrilutamide with another compound for full scalp coverage?

in Research/Science 6 upvotes 3 years ago

User uses 1ml RU58841 with 5ml stemoxydine for scalp coverage. Wants to switch to pyrilutamide and asks about mixing it with other compounds.

community Does anyone use Fluridil as their anti-androgen of choice?

in Chat 5 upvotes 2 years ago

Fluridil, a non-steroidal anti-androgen approved for alopecia in parts of Europe, is noted for its low side effects but is not commonly discussed. The user is inquiring if anyone prefers it over other anti-androgens like Spiro or RU58841.

community Eucapil, Fluridil update from manufacturer

in Treatment 5 upvotes 11 months ago

The user is experiencing hair loss after a hair transplant and is considering using fluridil (Eucapil) and possibly alfatradiol as treatments, as they couldn't tolerate finasteride or minoxidil. The manufacturer of Eucapil confirmed they won't produce higher concentrations due to lack of efficacy.

community Quitting Alfatradiol after 4 months

in Product 5 upvotes 1 year ago

The user stopped using Alfatradiol after 4 months due to no hair improvement and side effects like dry scalp and gallbladder pain. They are considering trying topilutamide, which is suggested as an alternative.

community Alfatradiol anyone? Anyone added it to their regimen and found it helps?

in Treatment 4 upvotes 4 years ago

Alfatradiol helps reduce hair shedding and itching, and is effective for mild hair loss. Users combine it with treatments like fluridil, minoxidil, and sometimes consider finasteride.

community Pyrilutamide with Alfatradiol and minoxidil (23M)

in Treatment 2 upvotes 6 months ago

The user experienced side effects from a hair loss treatment and is considering using pyrilutamide, alfatradiol, and possibly minoxidil. They are unsure about starting minoxidil immediately or waiting to see the effects of the other treatments.

community I think it’s time to drop Pyrilutamide at this point?….

in Update 29 upvotes 3 years ago

A user who has been using Pyrilutamide for 5 months with no results, and other users suggesting they switch to RU58841 or stick to their treatment plan for at least one year.

community Fluridil solution at Actifolic

in Treatment 4 upvotes 3 years ago

Fluridil, also known as Topilutamide or Eucapil, is discussed as a treatment for hair loss. It is noted as an androgen receptor antagonist, not a vasodilator.

community Pirfenidone - The answer to fibrosis and baldness

in Treatment 19 upvotes 4 years ago

Pirfenidone is suggested to treat fibrosis and baldness by blocking inflammation markers and reducing collagen. It is also available as a gel for scar removal.

community Alfatradiol!!! Does anyone use this as part of their stack and can actually comment on its effectiveness?

in Treatment 2 upvotes 1 year ago

Alfatradiol is used by some for hair loss, often alongside treatments like finasteride, RU58841, and minoxidil, but its effectiveness is unclear. Some users report no significant improvement, while others note reduced sebum production but experience side effects like gallbladder pain.

community I am doing an experience with RU58841

in Treatment 8 months ago

The conversation discusses a user experimenting with RU58841 for hair regrowth by ingesting it, which others find concerning. There are mentions of potential side effects and comparisons to other treatments like minoxidil, finasteride, and flutamide.