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Did you mean Gap Junctions?

GlossaryGap Junctions

Gap junctions are specialized intercellular connections that allow for direct communication between adjacent cells through the exchange of ions and small molecules. In the context of hair biology, they play a crucial role in maintaining the homeostasis of hair follicle cells and facilitating the signaling necessary for hair growth and cycling. Key distinguishing characteristics of gap junctions include their formation by connexin proteins, which assemble to create channels that bridge the cytoplasmic space between cells, enabling coordinated cellular responses that are vital for healthy hair follicle function. Disruption of gap junction communication can contribute to hair loss and other hair disorders.

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community Happiness is just a gap between sheds

in Progress Pictures 107 upvotes 4 months ago

A user shared their experience with hair loss treatments, switching from 1mg finasteride and topical minoxidil to 5mg oral minoxidil and oral dutasteride, noting improvements despite shedding phases. Other users discussed the hair growth cycle, treatment effects, and shared advice on managing hair loss, including buzzing hair and maintaining mental health.

community Running out of finasteride

in General 43 upvotes 9 months ago

The user completed their first month using oral finasteride and topical minoxidil without issues but is concerned about a 2-3 day gap in their finasteride supply affecting progress. They are also seeking advice on obtaining a multi-month supply.

community Important thing i discovered that makes ru58841 very effective

in Update 75 upvotes 2 months ago

RU58841 is more effective when mixed with isopropyl alcohol instead of minoxidil, as water in minoxidil degrades RU58841. Applying RU58841 separately from minoxidil, with an hour gap, enhances hair growth results.

community Adding topical Min and dermastamping to oral Min/Fin?

in Treatment 1 upvotes 2 months ago

The user has been using oral Minoxidil, Finasteride, and Biotin for hair recovery and is considering adding topical Minoxidil and dermastamping to improve results. It is suggested to use micro-needling once a week with a 24-hour gap before applying topical Minoxidil.

community Mixing minox with stemoxydine? As in mixing the solutions into one

in Minoxidil 2 upvotes 9 months ago

Mixing minoxidil and stemoxydine is not recommended due to potential dilution and reduced effectiveness. Applying them separately with a time gap is suggested.

community How to use topical minoxidil with Koshine826 - Kintor response

in Minoxidil 7 upvotes 1 year ago

The conversation discusses using minoxidil and Koshine for hair loss. It suggests applying them separately with a 5-minute gap and using Koshine on dry hair.

community How long will RU58841 remain effective after dosages are stopped?

in Product 2 upvotes 1 year ago

The conversation is about the effectiveness of RU58841 after stopping its use. The user is concerned about losing results if there's a 4-5 day gap before the next bottle arrives.

community Taking fin for 2 years, should I swap to dut?

in General 98 upvotes 6 months ago

The user has been using finasteride inconsistently for 2 years and minoxidil for 6 months without seeing hair growth. They are considering switching to dutasteride and restarting minoxidil to address thinning at the right temple, with advice suggesting consistent use for better results.

community How much hair loss in the shower is actually normal? My experience + what helped

in Product 8 upvotes 7 months ago

Hair shedding in the shower is normal, with 50-100 strands lost daily, but excessive shedding may indicate issues like low iron. Treatments like gentle hair care, iron supplements, and medications like minoxidil and finasteride can help reduce hair loss.

community How often to microneedle for optimal results

in Microneedling 10 upvotes 1 year ago

Microneedling for hair loss is discussed, with users suggesting different frequencies and needle lengths, such as 1.5mm every 3 to 6 weeks or 1.0mm weekly. Some users recommend less frequent sessions to avoid scalp damage and soreness.

community 10 months Minoxidil 2.5mg and 8 months Dutasteride 0.5mg - Before/After

in Progress Pictures 667 upvotes 1 year ago

A 29-year-old man used oral Minoxidil and Dutasteride for hair loss, seeing significant regrowth, especially in the crown area, but plans a hair transplant for the temples. Users suggest waiting longer before a hair transplant and trying additional treatments like microneedling and topical Minoxidil.

community 1mg Finasteride and 2.5mg minoxidil. (2 months)

in Progress Pictures 192 upvotes 2 years ago

A user started treating their hair loss with 1mg finasteride and 2.5mg minoxidil daily, and has seen progress in two months. They also use 2% ketoconazole shampoo twice a week and a derma stamp once a week with liquid minoxidil.

community my daily breakfast til the day i die

in Satire 649 upvotes 2 weeks ago

Using both finasteride and dutasteride for hair loss is debated, with some seeing it as beneficial during transition, while others find it redundant and risky. Oral minoxidil raises concerns about blood pressure, with a preference for topical use and microneedling for better results.

community How to properly combine topical Pyrilutamide (KX-826) and Minoxidil? Timing question.

in Minoxidil 1 upvotes 1 month ago

Combining topical minoxidil and pyrilutamide (KX-826) for hair loss treatment. It is suggested to apply minoxidil first, wait 20 minutes, then apply pyrilutamide for better absorption.

community Breezula Phase 3 confusion - did they change something?

in Chat 9 upvotes 2 months ago

Breezula's phase 2 showed reduced efficacy after 6 months, but phase 3 had positive results, causing confusion about any changes made to the drug. There is frustration over the long timeline for hair loss treatments, with some users expressing more interest in other potential treatments like GT-20029.

community Ok keep it real, is Fin not for me? Tried it 10 years ago

in General 172 upvotes 4 months ago

The user is considering trying finasteride again for hair loss despite past side effects like tender nipples and concerns about mental health impacts. They are advised to consult a doctor and consider topical or low-dose finasteride.

community Haïr différence after 1 year dut with alternate days

in Finasteride/Dutasteride 63 upvotes 4 months ago

The user experienced hair thickening and regrowth using dutasteride on alternate days, oral minoxidil every third day, and daily hair massages, but is dealing with dandruff and inflammation. They are considering adjusting their minoxidil dosage and have started using ketoconazole shampoo and cupping therapy for additional benefits.

community Microneedling + topical fin/min: how to structure the routine?

in General 78 upvotes 6 months ago

The user is using a topical spray containing finasteride, minoxidil, ketoconazole, and biotin for hair loss and plans to add weekly dermastamping, starting with a needle length of 0.6mm. They seek advice on the safety of combining these treatments, the impact of skipping one dose weekly, and the frequency of replacing the dermastamp.

community 2nd HT FOR CROWN AND MID SCALP.

in Transplants 2 upvotes 6 months ago

The user underwent a second hair transplant for the crown and mid-scalp, achieving good density. They are using minoxidil, finasteride, and biotin, and considering PRP treatments to enhance growth.

community Min, without fin. Worth it or no

in Minoxidil 104 upvotes 11 months ago

Minoxidil can be used alone to address thinning hair, but it may be less effective without finasteride. Minoxidil increases blood flow and may regrow some hair, but it doesn't block DHT.

community Switching from finasteride to dutasteride.

in Finasteride 76 upvotes 11 months ago

The user has been taking finasteride for nearly 5 years and is now adding dutasteride to their regimen to maintain hair loss prevention. They seek advice on transitioning from finasteride to dutasteride.

community 8 months apart - got all my hair back.

in Update 4805 upvotes 1 year ago

A user successfully regrew their hair over 8 months using topical minoxidil, finasteride, a healthy lifestyle, and derma stamping. They emphasize the results are genuine and not from hair transplants.

community 0.1% topical finesteride 2x per day. Is it too much?

in Finasteride 98 upvotes 1 year ago

The conversation discusses using a 0.1% topical finasteride solution twice daily after experiencing brain fog from oral finasteride. A user suggests trying the solution once daily for a few months if concerned.

community 1 year on finasteride am i still balding not seeing result

in Is this regrowth? 6 upvotes 1 year ago

The user has been using finasteride for a year but is experiencing thinning in some areas and is unsure how to proceed. Suggestions include trying minoxidil for regrowth or consulting a dermatologist about adjusting the finasteride dosage.

community Should I Switch to Oral Minoxidil While Continuing Dutasteride? Need Advice on Next Steps After Accelerated Shedding

in General 172 upvotes 1 year ago

The user is experiencing increased hair shedding and is considering switching from a topical solution containing minoxidil, finasteride, and tretinoin to oral minoxidil while continuing oral dutasteride. They are seeking advice on whether to make this switch or wait for the shedding to stabilize, and are concerned about potential side effects of oral minoxidil.

community My country is 100 years behind the US in treating hairloss

in Treatment 188 upvotes 1 year ago

In the Czech Republic, doctors are largely unaware of hair loss treatments beyond minoxidil, and finasteride is hard to obtain. Many users suggest buying treatments like finasteride and minoxidil from other countries or online.

community Anyone using oral castor oil in their stack?

in Treatment 3 upvotes 1 year ago

The conversation discusses using oral castor oil as a hair growth stimulant for beard and scalp hair. One user questions its use, noting castor oil is typically a laxative in the Philippines.

community Seeking Feedback on My Hair Transplant Results: Is My Hairline Proper?

in Progress Pictures 461 upvotes 2 years ago

The conversation is about a user sharing their hair transplant results and seeking feedback. They are taking finasteride, minoxidil, oral minoxidil, vitamins, and using special shampoo to maintain their hair.

community Fucking Broccoli! Is this where it's at?

in Treatment 2 upvotes 2 years ago

The user has been using finasteride and minoxidil for hair regrowth, with positive results, and recently added daily broccoli consumption, noticing improved hair thickness. Another user suggests that leg exercise, not broccoli, might be contributing to the hair improvement.

community RU58841 dilution in Minoxidil Vs PG+Ethanol

in Treatment 4 upvotes 2 years ago

RU58841 mixed with Minoxidil seems less effective over time, so the user plans to switch to a PG and Ethanol dilution for better results. They also consider using rosemary oil with Minoxidil to enhance RU58841 absorption.