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GlossaryGenetic Component

inherited influence on traits or conditions

The term "genetic component" refers to the part of a trait or condition that is influenced by genes inherited from one's parents. For example, in the context of hair loss or alopecia, the genetic component would be the specific genes that make an individual more susceptible to losing hair, which can be passed down through family lines. This concept is crucial for understanding how certain traits or diseases are inherited and can help in developing targeted treatments or interventions.

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community Galenic lotion. Science behind the components

in Treatment 1 upvotes 10 months ago

A user is considering a hair loss treatment lotion containing minoxidil, adenosine, caffeine, melatonin, and azelaic acid, questioning the interaction between caffeine and adenosine receptors. Another user suggests adding a topical anti-DHT ingredient like spironolactone, noting it should not be taken orally by men.

community How does hair loss and recovery work?

in Chat 12 upvotes 1 year ago

Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

community What are all of the lifestyle factors that can speed up MPB?

in Chat 39 upvotes 2 years ago

Genetics mainly cause hair loss, but diet, stress, smoking, and alcohol can worsen it. Treatments include finasteride, minoxidil, and lifestyle changes like a healthy diet and avoiding caffeine.

community Calling out diffuse thinners here -- Have you ruled out other factors?

in Treatment 54 upvotes 1 year ago

Diffuse hair loss is often linked to genetics but can also be due to health issues like thyroid problems and low vitamin or iron levels. Treatments include finasteride, minoxidil, and dutasteride, with some seeing improvements after addressing health issues.

community Comparison of products from Minimalist and Man Matters

in Product 4 upvotes 2 years ago

The conversation is about which hair loss treatment to recommend between Minimalist and Man Matters, with a request for advice based on their different components.

community Anyone else realize how many younger guys are balding?

in Chat 262 upvotes 1 year ago

Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

community 18->24 six years of Fin and Minox…. I guess we can’t all be winners 😭

in Progress Pictures 572 upvotes 3 years ago

A user named "EgyptStar81" who has been dealing with hair loss since age 15 due to genetics, chemotherapy and finasteride/minoxidil treatment. Possible solutions such as dutasteride, oral minoxidil, hair transplants and extensions were suggested.

community I saw a 5 in 1 is Dut and Minoxidyl and the 3 in 1 is Fin and Minoxidil chews or pills. Snake oil or not?

in Finasteride/Dutasteride 1 upvotes 1 month ago

The conversation discusses skepticism about "5 in 1" and "3 in 1" hair loss treatments, which combine Dutasteride or Finasteride with Minoxidil, being overpriced and potentially ineffective. Users suggest buying individual components separately for cost savings and question the effectiveness of low concentrations in these combined products.

community 80-year-old with his 99-year-old father have more hair than I did at 15

in Satire 1017 upvotes 1 month ago

An 80-year-old man and his 99-year-old father have more hair than many younger people, sparking discussions about hair loss and genetics. The suggested treatment for maintaining hair is simply eating oysters.

community Does dutasteride stop hair loss forever?

in Finasteride/Dutasteride 38 upvotes 1 year ago

Dutasteride and finasteride can significantly slow or halt hair loss, with some users experiencing regrowth, but results vary. Lifestyle factors and individual genetic predispositions also play a role in hair loss outcomes.

community Listen to anyone besides your Mom while fighting hair-loss

in Satire 464 upvotes 5 years ago

Hair loss treatments, with people sharing their experiences of trying to get help from family members and how genetics can affect the severity of hair loss. Treatments mentioned include finasteride, minoxidil, RU58841, scalp massage, whey protein and bleaching.

community Before and after pics with Microneedling + possible confounds

in Progress Pictures 4 upvotes 5 years ago

The user experienced hairline improvement using microneedling once a month with a 12-pin set at 1.5-2.0mm and taking Tru Niagen, alongside a heavily modified diet. They attribute the slow hairline improvement to environmental factors, particularly diet, rather than solely genetic factors.

community How is this even possible that there is no cure till now

in Technology 156 upvotes 2 weeks ago

There is no permanent cure for hair loss; treatments like finasteride, minoxidil, and hair transplants require ongoing use and are not universally effective. Genetic complexity and financial incentives for ongoing treatments hinder the development of a definitive cure.

community How is it that golden era bodybuilders kept their hair while blasting gear while in the modern era most are bald? I’m convinced there’s something in our food and water causing MPB to speed up

in Satire 726 upvotes 2 years ago

The conversation is about the difference in hair loss between bodybuilders in the "Golden Era" and modern bodybuilders. Some users speculate that factors such as the types and doses of steroids used, genetics, diet, microplastics, and overall health may contribute to hair loss. Hair loss prevention medication and transplants are mentioned as potential treatments.

community Only Minoxidil 2 Months Before After Photos

in Progress Pictures 132 upvotes 2 years ago

A user shared their 2-month hair growth progress using only Minoxidil, noting significant improvement and plans to continue despite a genetic predisposition to baldness. They apply Minoxidil twice daily, experienced a heat rash, and chose not to use Finasteride due to side effects.

community Has anyone over age 35+ succeeded with Fin, dut or min

in Finasteride/Dutasteride 14 upvotes 1 year ago

People over 35 have seen success with finasteride, minoxidil, and dutasteride for hair loss. Results vary, with some noticing improvements in hair volume and hairline, while others emphasize patience and managing expectations.

community What an amazing time to be alive

in Finasteride/Dutasteride 187 upvotes 2 years ago

The post discusses a user's experience with hair loss treatments, specifically topical finasteride, minoxidil, and micro-needling, and their plan to switch to oral versions and add Dutasteride. The conversation includes various responses, with some users sharing their own experiences and side effects, and others expressing desire for a more permanent hair loss solution.

community DHT Harms Scalp Microbiome: DHT Itch is REAL

in Research/Science 411 upvotes 1 year ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community Any bludfluw or placebo supplements to slow down graying?

in Product 2 upvotes 2 years ago

The user has accepted their hair loss and uses finasteride and minoxidil, with past use of RU58841 and dutasteride. They seek advice on supplements to slow down graying hair.

community Lilly to seek first approval of an autoimmune drug for hair loss

in Research/Science 19 upvotes 5 years ago

Eli Lilly's drug baricitinib showed effectiveness in treating alopecia areata, with higher doses resulting in significant hair regrowth compared to placebo. The treatment is not for male pattern baldness.

community 25f/Europe - Does anyone have leads on HT for women or knows of a woman who did it?

in Female 11 upvotes 7 years ago

A woman experiencing severe hair loss since age 20 is seeking advice on hair transplants for women. Minoxidil hasn't worked for her, and she's considering shaving her head or getting a wig.

community Bryan Johnson used a customized formula by Roots byGA to restore his hair

in Treatment 24 upvotes 1 year ago

Bryan Johnson used a customized hair restoration formula from Roots byGA, which includes Minoxidil, Cetirizine HCl, Latanoprost, Dutasteride, Melatonin, Caffeine, Tretinoin, Vitamin D3, and Vitamin E. Many users are skeptical of the effectiveness and uniqueness of the treatment, suggesting that standard treatments like Minoxidil and Dutasteride are more reliable.

community Painkillers May Block Minoxidil

in Research/Science 16 upvotes 1 year ago

Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

community Antihistamines stop my hair loss

in Treatment 23 upvotes 4 years ago

A user found that antihistamines stop their hair loss and related symptoms, but they experience side effects like sedation and chest pain. They are seeking alternative solutions or topical antihistamines to avoid systemic side effects.

community Redensyl for Hair Loss — What It Can and Can’t Do

in Treatment 2 upvotes 5 months ago

Redensyl is a plant-based treatment that may support hair regrowth by reactivating dormant follicles and improving hair density, especially in early-stage thinning. It is not a miracle cure and results vary; it is less proven than Minoxidil or Finasteride and may cause scalp irritation.

community Comeback is real from NW7?

in Treatment 66 upvotes 6 years ago

A 25-year-old who started losing hair at 16 and reached almost NW7 by 20 saw hair regrowth using a regimen including dutasteride, minoxidil, nizoral, and a dermaroller, along with supplements like biotin, zinc, and omega-3. After initial success, they experienced shedding, added more supplements and treatments, and sought advice on whether to continue; responses encouraged them to persist as shedding is often part of the hair regrowth cycle.

community Looking for advice on my mom’s hair loss – what actually works for women?

in Female 4 upvotes 3 months ago

Minoxidil and spironolactone are recommended for female hair loss, and they can be used together. A dermatologist visit is advised to confirm the type of hair loss and rule out other issues.

community Testosterone's Role In Androgenetic Alopecia

in Research/Science 11 months ago

DHT is essential for androgenetic alopecia, not testosterone. Treatments like finasteride and dutasteride reduce DHT, halting hair loss.

community 16month progress on crazy stack

in Finasteride/Dutasteride 8 upvotes 2 years ago

The user has been using a strong combination of hair loss treatments for 16 months, including Finasteride, Minoxidil, Dutasteride, and RU-58841, but their hair loss has worsened. They're questioning whether their high testosterone levels or residual scalp DHT are causing further hair loss, with a reply suggesting that even small amounts of DHT can cause hair loss if one is sensitive to it.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.