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GlossaryGenotype

genetic composition influencing traits and characteristics

Genotype refers to the genetic makeup of an organism, specifically the set of genes it carries. It determines various traits and characteristics, such as eye color or susceptibility to certain diseases, by influencing how the organism's cells function and develop. For example, in the context of hair, a person's genotype can influence whether they are predisposed to conditions like alopecia.

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community Using 23andme to insight minoxidil response / SULT1A1 activity

in Minoxidil 10 upvotes 4 years ago

The conversation discusses using 23andme to determine if someone might respond well to minoxidil for hair loss treatment, and mentions the user's personal experience with micro-needling and minoxidil.

community Rate my MPB Genetics: Can I run Primobolan/Masteron? (Detailed MyHeritage DNA Data Included)

in General 262 upvotes 2 weeks ago

The user is using testosterone and finasteride to prevent hair loss and is considering adding Primobolan or Masteron, which are DHT-derivatives. They are seeking advice on their genetic risk for male pattern baldness and whether they can safely use these compounds without significant hair loss.

community Dutasteride: More Than a DHT Reducer – A Potential Androgen Receptor Inhibitor?

in Finasteride/Dutasteride 31 upvotes 1 year ago

Dutasteride may inhibit androgen receptors in addition to reducing DHT, potentially explaining its effectiveness over finasteride for hair loss. Concerns about its impact on muscle growth are debated, with some suggesting no significant effects.

community 3 month progress dut

in Progress 309 upvotes 6 years ago

User experienced rapid thinning on crown, used dutasteride for 3 months with significant improvement. Microneedling and ketoconazole were also used, but no minoxidil or finasteride.

community I don’t think my hair loss is caused by DHT – quitting finasteride after 3 months (1 mg). Need opinions

in Finasteride/Dutasteride 1 month ago

The user plans to stop finasteride after three months, believing hair loss isn't due to DHT, and will continue with oral minoxidil, microneedling, and ketoconazole shampoo. They suspect stress and poor nutrition are the main causes and seek opinions on DHT blockers' effectiveness.

community Minoxidil works only with Retinoic acid

in Minoxidil 317 upvotes 8 months ago

Minoxidil is more effective when combined with retinoic acid, such as tretinoin or tazarotene, enhancing hair growth. Some users experience significant regrowth, while others see minimal effects or side effects.

community 30-Min Dermatology Visit – Best Questions to Ask About Balding? ( 175$ )

in Treatment 6 upvotes 1 year ago

The conversation discusses hair loss treatments, focusing on finasteride, minoxidil, and other options like PRP and ketoconazole. It highlights the importance of asking specific questions during a dermatology visit to determine the cause of hair loss and appropriate treatments.

community Why do so many people trash on finasteride?

in Chat 247 upvotes 1 year ago

Finasteride is effective for hair regrowth, especially on the crown, but can cause side effects like reduced libido and erectile dysfunction in some users. Opinions are mixed, with some reporting positive results without side effects and others experiencing significant issues.

community Follow up appointment with Donovan.

in Finasteride/Dutasteride 17 upvotes 2 years ago

The user was diagnosed with DUPA and initially treated with finasteride, then switched to dutasteride which worsened their hair loss. They are now returning to finasteride and adding treatments including oral minoxidil, Proscar, Viviscal, pumpkin seed oil, LLLT, and Nizoral shampoo, hoping for hair regrowth.

community Results of topical minoxidil 3 months

in Progress Pictures 67 upvotes 1 year ago

The user experienced significant hair regrowth using topical minoxidil but faced issues with gynecomastia when using oral minoxidil and finasteride. They plan to have surgery for gynecomastia and consider using finasteride again, while questioning if minoxidil alone can maintain hair growth.

community Anagenic is trying to compound Gt20029

in Treatment 57 upvotes 3 years ago

The conversation discusses concerns that Anagenic's version of GT20029 might not be as effective or safe as Kintor's, with comparisons to issues faced by pyrilutamide. The chemical structure of the drug has been published.

community Genetic testing to determine individualized hairloss treatment?

in Research/Science 10 upvotes 2 years ago

A user discusses a company, Roots by Genetic Arts, that offers a genetic test for hair loss to create personalized treatments, and is curious about its legitimacy and the science behind it. The company tests 16 genes related to hair loss and compounds a topical treatment based on the results.

community Finasteride and male phenotypes

4 upvotes 10 years ago

Finasteride's effectiveness and side effects may vary based on male phenotypes, with some users noting differences in response related to body and facial hair characteristics. Some users report success with lower doses, while others experience side effects, suggesting individual variability in response to the treatment.

community Genetic variations associated with response to Dutasteride. Why is it never mentioned?

in Research/Science 26 upvotes 1 year ago

Genetic variations influence how people respond to dutasteride for hair loss, with some benefiting more from finasteride. Dutasteride is effective for most, but genetic differences may cause it to be less effective for some.

community DNA Testing by Roots by Genetic Arts

in Research/Science 3 upvotes 2 years ago

A user shared their positive experience with Roots by GA, a company that creates personalized hair loss treatments based on DNA analysis, which confirmed their inability to tolerate finasteride. The user is satisfied with their progress 30 days after a hair transplant and the customized formula they received.

community actors that i don't think they ever used fin or min, they just have good gens

in Chat 581 upvotes 7 months ago

Some actors are believed to use treatments like finasteride, minoxidil, or hair transplants to maintain their hair, while others are thought to have naturally good genetics. Opinions vary on whether celebrities like Brad Pitt have natural hair or use enhancements.

community Genomic Sequencing for Hair Loss

in Research/Science 156 upvotes 2 weeks ago

Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.

community What the hell happened in my family genes?

in Chat 116 upvotes 1 year ago

A user is frustrated about early balding despite older male relatives retaining hair into old age. Another user plans to start finasteride soon to address their hair thinning.

community Testosterone and DHT levels through the roof yet has better hair than the majority of guys who are “healthy” genetics are everything

in Satire 554 upvotes 2 years ago

The conclusion of this conversation about hair loss is that genetics play a significant role in determining hair loss, and specific treatments like finasteride may not be effective against certain compounds like masteron and trenbolone.

community This guy won the jackpot in the hair genetics lottery. He had to pay the taxes (white hair) though

in Chat 2083 upvotes 8 months ago

A man with thick, white hair is admired for his genetics, leading to discussions about hair loss and the preference for white hair over balding. Some speculate about the use of treatments like finasteride.

community CRISPR treatment for AGA on the horizon after approval for blood disorders

in Treatment 10 upvotes 2 years ago

CRISPR treatments for blood disorders have been approved, leading to discussions about its potential for treating hair loss (AGA). A study showed that editing a gene related to DHT sensitivity could lead to hair regrowth, suggesting CRISPR may eventually be used for AGA, but it's expected to be expensive and not soon available.

community Is trichogram a good thing for testing genetic hair loss

in Research/Science 2 upvotes 1 month ago

A dermatologist checked for hereditary hair loss using blood tests and plans to perform a trichogram. The user had slightly low Vitamin D3 levels, and the trichogram may help confirm androgenetic alopecia.

community Do we know exactly why some people respond so great to dut/fin,min and others dont?

in Research/Science 29 upvotes 1 year ago

Genetic factors, enzyme activity, and DHT sensitivity affect individual responses to hair loss treatments like finasteride, minoxidil, and dutasteride. Starting treatments early can slow hair loss, but results vary among individuals.

community I want to sacrifice my hair in the name of science

in Chat 12 upvotes 2 years ago

The conversation discusses various theories of hair loss, including DHT sensitivity and genetic factors, with the user willing to use themselves for research due to having a hair loss gene but different hair loss patterns compared to their brothers. Specific treatments were not mentioned in the provided text.

community Odd Hair Growth (Possibly More Than Genetics?)

in Is this regrowth? 2 upvotes 1 year ago

A 23-year-old user shares their hair regrowth journey, questioning if genetics or other factors are at play. They use Rogaine, finasteride, vitamin B12, biotin, Thera M Plus, and derma stamping, and seek advice on their regimen and hair growth patterns.

community Genetics are so weird and unpredictable

in Minoxidil 118 upvotes 1 year ago

The user experienced male pattern baldness starting at 18, tried finasteride with no success, and switched to dutasteride, which halted hair loss. Minoxidil had no effect for them, while their brother, who didn't use AR inhibitors, maintained a juvenile hairline and successfully grew a beard with minoxidil, highlighting the unpredictable nature of genetics in hair loss and treatment response.

community Eliminate/Confirm AGA based on blood report

in General 126 upvotes 9 months ago

A 19-year-old male with no family history of androgenetic alopecia (AGA) is experiencing hair loss and considering using a topical minoxidil and finasteride mixture. Despite low vitamin D levels and normal DHT serum levels, he seeks confirmation of AGA before starting treatment.

community DNA Test for better suited treatment?

in Treatment 3 upvotes 6 months ago

The conversation is about hair loss treatments, specifically discussing the use of dutasteride, minoxidil, and the potential benefits of a DNA test and PRP therapy. Opinions vary, with some users skeptical about the DNA test and PRP, suggesting sticking with current treatments.

community 5ar alpha reductase stimulation is different depending on whether it’s type 1 or 2

in Hair Systems 16 upvotes 2 years ago

The conversation discusses how different factors can stimulate type 1 and type 2 isoforms of 5-alpha reductase, which are enzymes linked to hair loss. Specific treatments mentioned include oral Dutasteride and topical Finasteride.

community 17, Concerned About Genetics and Effectiveness of DHT Blockers

in Basic Questions 101 upvotes 3 weeks ago

A 17-year-old is concerned about potential hair loss due to maternal genetics and wonders if treatments like Minoxidil, Finasteride, or RU58841 will be effective. They hope their paternal genetics will help prevent hair loss or make treatments more effective.