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GlossaryHyperammonemia

condition with elevated ammonia levels in the blood

Hyperammonemia is a condition characterized by elevated levels of ammonia in the blood. Ammonia is a waste product that is typically processed by the liver and converted into urea, which is then excreted in urine. When the liver is unable to effectively process ammonia, due to liver disease or genetic disorders affecting the urea cycle, it can accumulate in the bloodstream and become toxic, potentially leading to neurological symptoms such as confusion, lethargy, and in severe cases, coma.

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community Better Than Minoxidil? Topical Sodium Valproate

in Research/Science 53 upvotes 1 year ago

Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

community Helicobacter's concocted serum v1

6 upvotes 7 years ago

A custom-made serum based on double-blind studies for AGA, which includes natural ingredients such as rosemary oil, procyanidin B-2, saw palmetto extract, curcuma aeruginosa, pumpkin seed oil and castor oil. The user has updated their recipe to include apple poly procyanidin B-2 4% concentration and other ingredients before topping it off with Pura d'or serum.

community Thoughts on my dermatologist only giving me methionine for AGA?

in Treatment 4 upvotes 4 years ago

A dermatologist prescribed methionine with vitamins for hair loss, but the user is doubtful and plans to seek finasteride in France. The user is unsure why finasteride or minoxidil wasn't prescribed, suspecting concerns about side effects or strength.

community Rare case: AGA recovery with vitamin D alone (case study)

in Treatment 49 upvotes 3 months ago

Vitamin D deficiency can hinder hair recovery, and addressing it may help with hair loss. Hair loss may result from various issues like excess DHT, vitamin deficiency, or scalp inflammation.

community Can amino acids help with AGA

in Chat 4 upvotes 2 years ago

Amino acids like lysine, methionine, and cysteine may help with androgenetic alopecia when taken in high doses along with a DHT blocker. Users discuss combining these with treatments like Minoxidil, finasteride, and RU58841.

community HMI 115 hasn't done phase one yet for AGA?

in Research/Science 6 upvotes 3 years ago

User asks if HMI 115 hasn't done phase 1 for AGA in humans. Conversation includes treatments Min, Fin, and RU.

community Methionine? Glycine?

6 upvotes 10 years ago

The conversation discusses the potential benefits and risks of using Methionine and Glycine for hair loss, with concerns about cancer risk if not balanced properly. The user seeks opinions on these amino acids for hair health and overall benefits.

community May have been mis-diagnosed for 10 years, self-investigation into AGA + AA Incognita (Defused Shedding)

in Treatment 1 upvotes 1 year ago

A 27-year-old male with AGA and diffused thinning has been using oral Minoxidil, Finasteride, Vitamin D, B12, Iron, and Ketoconazole shampoo. Despite a hair transplant and improved blood levels, he continues to experience hair loss and suspects a possible misdiagnosis of Alopecia Areata Incognita.

community AA and Hirsutism but T levels are normal

in Female 5 upvotes 5 years ago

27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

community Anyone had anemia + AGA/thinning ?

in Treatment 4 upvotes 1 year ago

OP experienced significant hair regrowth after recovering from iron deficiency anemia and starting minoxidil. They suspect anemia contributed more to their hair loss than androgenetic alopecia (AGA).

community Clinical Trial: N-Acetyl-Cysteine for Treatment of AGA in Men

in Treatment 4 upvotes 5 years ago

N-Acetyl-Cysteine (NAC) is being explored for treating hair loss, but users report mixed results. Some also mention using Quercetin and Resveratrol without significant hair improvement.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Lowering scalp prolactine - Any ideas ?

in Treatment 2 upvotes 2 years ago

The conversation is about finding the best method to lower scalp prolactine, with suggestions like P5P and Melatonin. The user also mentions HMI115 as a potential treatment and seeks feedback from those who have tried these methods.

community Can Whey Protein isolate make your AGA worse?

in Product 9 upvotes 3 years ago

Whey protein isolate may worsen androgenetic alopecia (AGA) due to its potential to increase DHT levels, but finasteride use has helped maintain hair. Some users suggest avoiding protein supplements due to possible contaminants and additives that could affect hair health.

community Could Serum Ferritin Explain my Crazy Shedding?

in Treatment 1 upvotes 6 months ago

The user is experiencing significant hair shedding and suspects it may be due to low serum ferritin levels rather than worsening androgenetic alopecia. They have resumed iron supplementation and are seeking additional solutions to address the shedding.

community Whey Protein can cause hairloss in men with AGA as per a doctor

in Research/Science 63 upvotes 6 months ago

Whey protein may slightly increase hair loss in men with androgenetic alopecia (AGA) due to elevated IGF-1 and testosterone levels, but the effect is minimal compared to treatments like finasteride and dutasteride. Many users argue that whey protein's impact on hair loss is negligible and that maintaining a healthy lifestyle is more important.

community My good/bad experience with Creatine

in Treatment 26 upvotes 1 year ago

Creatine may cause increased hair shedding in some individuals, especially those with androgenetic alopecia (AGA), despite its physical performance benefits. Many users report stopping creatine to reduce hair loss, while others believe the effects are anecdotal or due to other factors like increased physical activity.

community possible treatment of AGA and change in sebaceous gland condition and oil production using sulfur soap

in Research/Science 4 upvotes 8 months ago

Sulfur soap may help with hair thickening and reducing scalp inflammation, but it can cause dryness. Nizoral, containing ketoconazole, is noted for its potential to reduce seborrheic dermatitis but may also cause scalp dryness and hair loss.

community I have heard that Amplifica - Scube3 initiate a human study for AGA, but I cannot find any information about it from clinictrial.gov. Amplifica did not state it is a phase 1 clinic trial or not, it says it is "The initiation of our first-in-human clinical study"

in Technology 2 upvotes 2 years ago

The conversation is about a user seeking information on a clinical trial by Amplifica - Scube3 for Androgenetic Alopecia (AGA). The user is unsure if it's a formal phase 1 study.

community 5ARI (dutasteride) Associated with Adverse Metabolic Effects

22 upvotes 8 years ago

Dutasteride is associated with increased blood glucose, HbA1c, LDL cholesterol, and liver enzyme activity, potentially leading to diabetes, NAFLD, and liver metabolism changes. The conversation highlights concerns about these adverse effects and calls for more studies, including on finasteride.

community Hair loss - Blood work (High DHEAS)

in Research/Science 9 upvotes 4 years ago

A user has been taking finasteride for 5 months with no improvement in diffuse hair loss and suspects high levels of prolactin, cortisol, progesterone, and DHEAS, as well as iron, might be contributing to the issue. They are also taking vitamin D to address a deficiency.

community 14 year old struggling with hair loss

in Treatment 7 upvotes 4 years ago

A 14-year-old is experiencing significant hair loss and was prescribed Aminexil by a dermatologist. They are concerned about potential side effects.

community Having AGA as a girl makes me depressed

in Female 65 upvotes 4 months ago

A 20-year-old woman with androgenetic alopecia feels depressed about her hair loss, despite using topical minoxidil, spironolactone, and saw palmetto. Suggestions include trying oral minoxidil, higher doses of finasteride or dutasteride, and checking for vitamin deficiencies and heavy metal exposure.

community sebum overproduction on fin 1mg and hair thinning

in Finasteride/Dutasteride 3 upvotes 2 years ago

User is experiencing hair thinning and sebum overproduction after starting finasteride and a hair growth supplement containing biotin, iron, zinc, and calcium. They suspect the finasteride might be fake but have noticed a side effect of watery semen.

community Malabsorption: Nutrient Testing and Supplementation

in Treatment 2 upvotes 1 year ago

The user is experiencing severe hair loss due to gut malabsorption and is seeking advice on nutrient testing and supplementation. They have low Vitamin D and Ferritin levels and are asking for recommendations on additional nutrients and blood tests to consider.

community Best Treatment In The Pipeline?

in Chat 15 upvotes 2 years ago

New treatments for AGA are emerging, including pyrilutumide, gt0029, scube3, kx-826, and pp405. Verteporfin is mentioned as a promising option.

community Eliminate/Confirm AGA based on blood report

in General 126 upvotes 1 year ago

A 19-year-old male with no family history of androgenetic alopecia (AGA) is experiencing hair loss and considering using a topical minoxidil and finasteride mixture. Despite low vitamin D levels and normal DHT serum levels, he seeks confirmation of AGA before starting treatment.

community Increased b12 and hair loss correlation

in Female 2 upvotes 2 years ago

A user noticed increased hair loss after taking B12 supplements for two months, with B12 levels rising to 1500. They are seeking help as other tests show normal levels of minerals and vitamins.

community Amplifica and AMP-303 clinical phase 1

in Research/Science 9 upvotes 2 years ago

Amplifica is testing a compound called AMP-303 for hair loss, but it's not Scube3 or osteopontin. The timing for the results from the clinical trial is unknown.

community Head itch even though I use keto shampoo

in Ketoconazole 3 upvotes 1 year ago

The user experiences scalp itchiness despite using ketoconazole shampoo and is also taking oral finasteride and minoxidil. Suggestions include trying different shampoos like Head & Shoulders, using salicylic acid products, considering allergies, and consulting a dermatologist for alternatives like Ciclopirox.