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      community The case for 5ARI-free hair transplants: Dr. Zarev, Pittella, Sethi, Miln, and future treatments in development

      in Treatment  14 upvotes 9 months ago
      Some individuals experience side effects from 5AR inhibitors like finasteride and are considering hair transplants without these medications, with some opting for surgeons like Dr. Zarev. Others are exploring alternative treatments and waiting for new medications in development, while some discuss managing side effects through lifestyle changes or additional medications.

      community I hate what my hair does to me!

      in Chat  32 upvotes 2 years ago
      The conversation is about a person struggling with inconsistent hair styling due to thinning hair, despite being on hair loss medications. They find that ketoconazole 2% shampoo helps, but conditioning makes their hair look worse; others suggest staying consistent with treatment and using hair fibers for events.

      community Fighting Hair loss AND Grey Hair

      in Treatment  19 upvotes 3 years ago
      The user is treating hair loss with topical Minoxidil, Finasteride, RU58841, microneedling, and Ketoconazole. For grey hair, they use L-Cysteine, L-Methionine, and PABA, and have noticed some re-pigmentation.

      community Concern about my hair loss escalation

      in Transgender 1 year ago
      The user is experiencing significant hair loss and has tried treatments like PRP therapy, topical and oral Minoxidil, Finasteride, and dietary changes, with limited success. They are concerned about losing more hair before a scheduled hair transplant and are advised to postpone the transplant to allow medications more time to work.

      community Verteporfin day 119 update - donor hair regeneration human trial

      in Research/Science  146 upvotes 3 years ago
      A human trial of verteporfin, a drug that can inhibit wound healing by scarring and promote regeneration of original tissue and hair follicles to provide an unlimited source for hair transplants; people discussed the potential of this drug and how it could be rolled out in mainstream with more doctors getting on board.

      community Treating MPB while dealing with seborrheic dermatitis?

      in Treatment  8 upvotes 2 years ago
      The user is seeking advice on treating male pattern baldness (MPB) while dealing with seborrheic dermatitis, specifically asking about the use of finasteride (Fin) and minoxidil (Min). They are concerned about side effects and are looking for recommendations to improve overall hair thickness, especially on the crown.

      community Question.. ( Come check )

      7 years ago
      A user has been losing hair for two and a half years after a tropical trip and illness. A dermatologist prescribed betamethasone valerate 0.1% lotion, but the user is unsure if it's safe or effective for general hair loss.

      community In God We Trust, Topical Fin/Min with existing ADHD issues

      in Chat  19 upvotes 1 year ago
      A 27-year-old male with ADHD is experiencing hair thinning and is starting a treatment with topical finasteride (0.025%) and minoxidil (5%). He is addressing high prolactin levels and low vitamin D, while managing side effects from ADHD medication.

      community Jxl069 (pp405 api) week 8 update

      in Progress Pictures  200 upvotes 11 months ago
      The user shared minimal results from using JXL-069 for hair loss, noting a slight lengthening of vellus hairs and plans to switch to a prodrug variant due to limited effectiveness. They also mentioned using finasteride and minoxidil, which have plateaued in results.

      community Zix pre-made - zinc topical on scalp

      in Treatment  3 upvotes 11 months ago
      The user is experimenting with a zinc sulfate and B6 topical solution called "Zix" for hair loss, alongside using a zinc oxide scalp mask and low-level laser therapy (LLLT). They report minimal hair loss after three months of use and are seeking feedback from others who have tried similar treatments.

      community 18M Diffuse thinning with 7ng/mL Vit D. Is it just the deficiency or is 0.5mg Fin mandatory?

      in Finasteride/Dutasteride  6 upvotes 5 months ago
      An 18-year-old with diffuse hair thinning is considering switching from a topical Minoxidil 10% + Finasteride 0.1% solution to Minoxidil 5% foam and oral Finasteride 0.5mg, while also addressing vitamin D deficiency and potential scalp inflammation. Users suggest using Nizoral shampoo for inflammation, considering dutasteride for better results, and maintaining vitamin D levels to protect hair follicles from DHT.

      community Does anyone know the chemical formula for pelage pp405?

      in Research/Science  14 upvotes 1 year ago
      The conversation discusses the lack of public information on the chemical structure of PP405, a hair loss treatment, and the challenges of synthesizing it without a patent. It also explores a patent related to hydrogen-based topical formulations for reducing oxidative stress and inflammation.

      community The MPB itch aka DHT itch is very real.

      in Chat  9 upvotes 3 years ago
      Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

      community Why doesn't phase 3 of PP405 start straight away?

      in Chat  14 upvotes 7 months ago
      Pelage is delaying the start of phase 3 trials for PP405 to 2026 due to necessary regulatory processes, despite having $120 million in funding. Users discuss the potential of PP405 for hair regrowth, with some expressing skepticism and others hopeful for new treatments like Breezula.

      community Pili migrans? Lichen something? Seb derm?

      in Female  19 upvotes 1 year ago
      The conversation is about a female experiencing hair loss and seeking advice on why it's difficult to regrow hair. Specific treatments like Minoxidil, finasteride, or RU58841 are not mentioned.

      community Noticed a form of hairloss at 15 (for a few months now)

      in General  52 upvotes 1 year ago
      A 15-year-old is experiencing hair loss and is considering treatment options. They are aware they cannot use DHT blockers like finasteride due to their age and are exploring other causes like Telogen Effluvium.

      community Potential way to differentiate good and bad sheds?

      in Treatment  3 upvotes 3 years ago
      User discusses hair loss treatments, including fluridil, minoxidil, tretinoin, melatonin, stemoxydine, ketoconazole, and piroctone olamine. They suggest that shedding healthy terminal hairs may be bad, while shedding weaker hairs could indicate a beneficial treatment effect.

      community will pp405 be able to bring my lost temple area back to the game?

      in Research/Science  10 upvotes 4 months ago
      A user is concerned about hair loss in the temple area despite using Minoxidil and finasteride for 10 months and is curious if PP405 can help. Responses indicate uncertainty about PP405's effectiveness, with some optimism about future treatments and AI speeding up drug discovery, but emphasize waiting for clinical trial results.