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GlossaryIfosfamide

chemotherapy drug that interferes with cancer cell DNA

Ifosfamide is a chemotherapy drug used to treat various types of cancer, including lymphomas and sarcomas. It works by interfering with the DNA of cancer cells, preventing them from growing and dividing. However, it can also cause side effects like hair loss (alopecia) and damage to the bladder and kidneys, so it is often administered with protective agents to mitigate these risks.

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community Pyrilutamide available at Actifolic now

in Research/Science 15 upvotes 4 years ago

Pyrilutamide, a new hair loss product with the potential to be more effective than RU58841 and safer than CB, but expensive.

community Pirfenidone - The answer to fibrosis and baldness

in Treatment 19 upvotes 4 years ago

Pirfenidone is suggested to treat fibrosis and baldness by blocking inflammation markers and reducing collagen. It is also available as a gel for scar removal.

community Megadosing Koshine826(Pyrilutamide), my Plan.

in Treatment 1 upvotes 1 year ago

The user plans to use 1% Koshine826, 0.1% Alfatradiol, Minoxidil with Tretinoin, microneedling, and Stemoxydine for hair loss treatment. They expect significant recovery with this regimen.

community pyrilutamide solution progress log

in Product 20 upvotes 3 years ago

A 28 year old using a hair loss prevention protocol to restore thinning hair, which includes finasteride, dutasteride, minoxidil, stemoxydine, alopecin, nizoral shampoo and microneedling; the user is now adding pyrilutamide solution to the regimen with the hope of improving their results. RU58841 was also ordered but not yet used.

community Pyrilutamide cease and desist from Kintor

in Transplants 12 upvotes 3 years ago

Considering a hair transplant, using Pyrilutamide, the potential availability of CosmeRNA, and the significance of taking Minoxidil and Finasteride for long-term results.

community Pyrilutamide with Alfatradiol and minoxidil (23M)

in Treatment 2 upvotes 8 months ago

The user experienced side effects from a hair loss treatment and is considering using pyrilutamide, alfatradiol, and possibly minoxidil. They are unsure about starting minoxidil immediately or waiting to see the effects of the other treatments.

community Is anoying mixing pyrilutamide with another compound for full scalp coverage?

in Research/Science 6 upvotes 3 years ago

User uses 1ml RU58841 with 5ml stemoxydine for scalp coverage. Wants to switch to pyrilutamide and asks about mixing it with other compounds.

community 0.25 alfatradiol or 0.5 Pyrulitamide ?

in Product 4 upvotes 9 months ago

The conversation is about choosing an anti-androgen for hair loss treatment, with options being alfatradiol and pyrilutamide. Alfatradiol is considered a better choice due to its established use, while pyrilutamide is more experimental.

community Pyrilutamide - Worth it if can’t use Fin?

in Research/Science 4 upvotes 1 year ago

Pyrilutamide is being discussed as an alternative for those who can't use finasteride, but users report it may be ineffective at low concentrations. Some users are combining it with minoxidil, microneedling, and other treatments, but results vary.

community I'm very skeptical about pyrilutamide

in Product 2 upvotes 5 months ago

Pyrilutamide's effectiveness is questioned due to overstated claims and previous trial ineffectiveness, with some users opting for finasteride instead. Despite skepticism, some consider adding pyrilutamide to their regimen alongside treatments like bicalutamide.

community Pyrilutamide vs enzalutamide. Same thing?( Especially for biochemists, farmacologists)

in Research/Science 17 upvotes 3 years ago

Researching whether pyri and enza, which are stereoisomers of each other, share the same features related to CNS penetration/GABA Inhibition; safety and efficacy when used topically at 0.5-1%; and cost comparison between the two treatments.

community Koshine 826 (Pyrilutamide). Any results after 5 months since it's been released?

in Product 12 upvotes 1 year ago

Koshine 826 (Pyrilutamide) has mixed reviews, with some users experiencing side effects like insomnia and others seeing minimal results. Concerns about the company's transparency and lack of progress photos are noted.

community Pyrilutamide +Alfatradiol 0.1% , no Hairloss anymore

in Treatment 43 upvotes 1 year ago

OP experienced diffuse thinning for 11 years and used Minoxidil and Finasteride previously. They now use Pyrilutamide 0.5% and Alfatradiol 0.1%, resulting in significantly reduced hair loss.

community Pyrilutamide is literally my only hope

in Chat 91 upvotes 3 years ago

Considering treatments for hair loss, including Minoxidil, Finasteride, RU58841, Fluridil and Pyrilutamide. The user is weighing the risks of taking unapproved medication before it has been mass produced.

community Kintors interim report from 9-2-24 for everyone whos interested

in Product 33 upvotes 1 year ago

Kintor plans to release pyrilutamide foam and a plant-based Koshine by year-end, with GT20029 progressing in their pipeline. Users are pleased about the absence of propylene glycol (PG) in the new products.

community Pyrilutamide should not be mixed with Minoxidil?

in Product 6 upvotes 3 years ago

Pyrilutamide should not be mixed with Minoxidil because the water in Minoxidil can degrade it. It's suggested to apply Minoxidil first, wait an hour, then apply Pyrilutamide.

community bicalutamide or spironolactone for fphl

in Female 6 upvotes 3 years ago

Bicalutamide and spironolactone are being compared for their effectiveness and safety in treating female pattern hair loss. The conversation seeks advice on which is better to use.

community Does anyone take bicalutamide for fphl? If so which dose

in Female 4 upvotes 3 years ago

The conversation is about a female seeking advice on using bicalutamide for female pattern hair loss (FPHL) and considering switching from pumpkin seed oil pills to a stronger treatment. She is looking for dosage information to discuss with her dermatologist.

community Pyrilutamide vs topical finasteride

in Finasteride/Dutasteride 2 upvotes 1 year ago

The user is considering switching to topical finasteride or pyrilutamide to stabilize hair loss before a hair transplant, currently using oral minoxidil and finasteride. Suggestions include sticking to the current regimen as it is already potent, and caution against using pyrilutamide from unreliable sources.

community Can’t do finasteride. Does this automatically cross out Pyrilutamide?

in Research/Science 3 upvotes 3 years ago

Hair loss discussion includes finasteride intolerance and questioning if Pyrilutamide is an alternative. Pyrilutamide not commercially available, but may be tolerable if approved since it's not a 5aR inhibitor.

community Homemade pyri solution- problems

in Treatment 1 upvotes 2 years ago

A user mixed a pyrilutamide solution and noticed undissolved powder at the bottom, questioning if this is normal and how long to wait before applying it. They wished others good luck with their treatments.

community Pyrilutamide - your experience?

in Product 12 upvotes 3 years ago

The conversation is about the lack of improvement in hair loss after using Pyrilutamide for 14 weeks, with the original poster unable to use Finasteride due to depression. Replies suggest that Pyrilutamide, like RU58841, may not work for everyone, and a more potent drug is being developed by Kintor.

community Pyrilutamide almost for 9 months

in Progress Pictures 62 upvotes 2 years ago

The user has been using pyrilutamide, topical finasteride, and 15% minoxidil for hair growth for almost 4 years. Despite mixed responses from others, the user reports seeing progress, especially with the addition of pyrilutamide, and plans to continue the regimen.

community Pyrilutamide or RU or cb-03-01?

in Minoxidil 2 upvotes 8 months ago

The conversation discusses using Minoxidil, finasteride, RU58841, and pyrilutamide for hair loss treatment. The user is considering adding a topical treatment and has not experienced side effects from current treatments.

community Pyrilutamide 0.5 or 0.025% topical fin for maintaining?

in Basic Questions 91 upvotes 2 months ago

The user is considering switching from pyrilutamide to 0.025% topical finasteride due to concerns about effectiveness and past side effects from a scalp elixir. They aim to maintain hair until new treatments like breezula or GT00029 become available.

community discouraged about pyrilutamide

in Research/Science 11 upvotes 3 years ago

Discouragement regarding Pyrilutamide, a drug in development for hair loss, and the potential side effects of Finasteride. People discussed anecdotal experiences with Pyrilutamide as well as suggestions to wait out Phase 3 trials before making any conclusions.

community Actifollic Will sell pyrilutamide😱

in Treatment 18 upvotes 4 years ago

Actifollic selling Pyrilutamide as a treatment for hair loss, with people debating its efficacy compared to Minoxidil and Finasteride in combination with RU58841.

community Pyrilutamide and RU alternatives?

in Treatment 1 upvotes 1 year ago

Pyrilutamide is officially available for purchase, and users suggest Fluridil as an alternative topical anti-androgen. Some users report positive results with pyrilutamide from Koshine.

community pyrilutamide log from someone who couldnt take fin/min/ru due to sideeffects

in Progress Pictures 105 upvotes 3 years ago

A user (seblt) who has had side effects from finasteride, minoxidil and RU58841 but is now trying pyrilutamide as a last resort, with other users providing advice and support. They have already seen some baby hairs growing after 10-14 days of treatment and will provide updates in 1-2 weeks.

community Guys I actually can’t believe pyrilutamide is actually working!!

in Product 25 upvotes 2 months ago

Hair regrowth was achieved using minoxidil, nizoral, alfatrodial, and pyrilutamide after finasteride caused side effects. The user recommends this combination for those who can't tolerate 5AR inhibitors, stressing consistent use.