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GlossaryIfosfamide

chemotherapy drug that interferes with cancer cell DNA

Ifosfamide is a chemotherapy drug used to treat various types of cancer, including lymphomas and sarcomas. It works by interfering with the DNA of cancer cells, preventing them from growing and dividing. However, it can also cause side effects like hair loss (alopecia) and damage to the bladder and kidneys, so it is often administered with protective agents to mitigate these risks.

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community Pyrilutamide available at Actifolic now

in Research/Science 15 upvotes 3 years ago

Pyrilutamide, a new hair loss product with the potential to be more effective than RU58841 and safer than CB, but expensive.

community Pirfenidone - The answer to fibrosis and baldness

in Treatment 19 upvotes 4 years ago

Pirfenidone is suggested to treat fibrosis and baldness by blocking inflammation markers and reducing collagen. It is also available as a gel for scar removal.

community Megadosing Koshine826(Pyrilutamide), my Plan.

in Treatment 1 upvotes 1 year ago

The user plans to use 1% Koshine826, 0.1% Alfatradiol, Minoxidil with Tretinoin, microneedling, and Stemoxydine for hair loss treatment. They expect significant recovery with this regimen.

community IVF process on Finasteride and effects of stopping finasteride.

in Finasteride/Dutasteride 135 upvotes 4 months ago

Concerns about finasteride affecting sperm quality and embryo abnormalities during IVF. The user plans to stop finasteride for 6 months and use minoxidil, microneedling, a red light cap, and saw palmetto shampoo to manage hair loss.

community Pyrilutamide cease and desist from Kintor

in Transplants 12 upvotes 3 years ago

Considering a hair transplant, using Pyrilutamide, the potential availability of CosmeRNA, and the significance of taking Minoxidil and Finasteride for long-term results.

community Pyrilutamide from Ligand Chem in the UK

in Research/Science 4 upvotes 3 years ago

community Pyrilutamide - Worth it if can’t use Fin?

in Research/Science 5 upvotes 10 months ago

Pyrilutamide is being discussed as an alternative for those who can't use finasteride, but users report it may be ineffective at low concentrations. Some users are combining it with minoxidil, microneedling, and other treatments, but results vary.

community pyrilutamide solution progress log

in Product 20 upvotes 3 years ago

A 28 year old using a hair loss prevention protocol to restore thinning hair, which includes finasteride, dutasteride, minoxidil, stemoxydine, alopecin, nizoral shampoo and microneedling; the user is now adding pyrilutamide solution to the regimen with the hope of improving their results. RU58841 was also ordered but not yet used.

community Pyrilutamide with Alfatradiol and minoxidil (23M)

in Treatment 2 upvotes 4 months ago

The user experienced side effects from a hair loss treatment and is considering using pyrilutamide, alfatradiol, and possibly minoxidil. They are unsure about starting minoxidil immediately or waiting to see the effects of the other treatments.

community Is anoying mixing pyrilutamide with another compound for full scalp coverage?

in Research/Science 4 upvotes 3 years ago

User uses 1ml RU58841 with 5ml stemoxydine for scalp coverage. Wants to switch to pyrilutamide and asks about mixing it with other compounds.

community Pyrilutamide vs enzalutamide. Same thing?( Especially for biochemists, farmacologists)

in Research/Science 17 upvotes 3 years ago

Researching whether pyri and enza, which are stereoisomers of each other, share the same features related to CNS penetration/GABA Inhibition; safety and efficacy when used topically at 0.5-1%; and cost comparison between the two treatments.

community 0.25 alfatradiol or 0.5 Pyrulitamide ?

in Product 5 upvotes 6 months ago

The conversation is about choosing an anti-androgen for hair loss treatment, with options being alfatradiol and pyrilutamide. Alfatradiol is considered a better choice due to its established use, while pyrilutamide is more experimental.

community Kintors interim report from 9-2-24 for everyone whos interested

in Product 32 upvotes 1 year ago

Kintor plans to release pyrilutamide foam and a plant-based Koshine by year-end, with GT20029 progressing in their pipeline. Users are pleased about the absence of propylene glycol (PG) in the new products.

community Koshine 826 (Pyrilutamide). Any results after 5 months since it's been released?

in Product 12 upvotes 1 year ago

Koshine 826 (Pyrilutamide) has mixed reviews, with some users experiencing side effects like insomnia and others seeing minimal results. Concerns about the company's transparency and lack of progress photos are noted.

community Pyrilutamide +Alfatradiol 0.1% , no Hairloss anymore

in Treatment 43 upvotes 1 year ago

OP experienced diffuse thinning for 11 years and used Minoxidil and Finasteride previously. They now use Pyrilutamide 0.5% and Alfatradiol 0.1%, resulting in significantly reduced hair loss.

community Pyrilutamide vs topical finasteride

in Finasteride/Dutasteride 2 upvotes 9 months ago

The user is considering switching to topical finasteride or pyrilutamide to stabilize hair loss before a hair transplant, currently using oral minoxidil and finasteride. Suggestions include sticking to the current regimen as it is already potent, and caution against using pyrilutamide from unreliable sources.

community Does anyone take bicalutamide for fphl? If so which dose

in Female 4 upvotes 3 years ago

The conversation is about a female seeking advice on using bicalutamide for female pattern hair loss (FPHL) and considering switching from pumpkin seed oil pills to a stronger treatment. She is looking for dosage information to discuss with her dermatologist.

community Pyrilutamide almost for 9 months

in Progress Pictures 62 upvotes 2 years ago

The user has been using pyrilutamide, topical finasteride, and 15% minoxidil for hair growth for almost 4 years. Despite mixed responses from others, the user reports seeing progress, especially with the addition of pyrilutamide, and plans to continue the regimen.

community bicalutamide or spironolactone for fphl

in Female 6 upvotes 3 years ago

Bicalutamide and spironolactone are being compared for their effectiveness and safety in treating female pattern hair loss. The conversation seeks advice on which is better to use.

community I'm very skeptical about pyrilutamide

in Product 2 upvotes 2 months ago

Pyrilutamide's effectiveness is questioned due to overstated claims and previous trial ineffectiveness, with some users opting for finasteride instead. Despite skepticism, some consider adding pyrilutamide to their regimen alongside treatments like bicalutamide.

community Pyrilutamide is literally my only hope

in Chat 91 upvotes 3 years ago

Considering treatments for hair loss, including Minoxidil, Finasteride, RU58841, Fluridil and Pyrilutamide. The user is weighing the risks of taking unapproved medication before it has been mass produced.

community discouraged about pyrilutamide

in Research/Science 11 upvotes 3 years ago

Discouragement regarding Pyrilutamide, a drug in development for hair loss, and the potential side effects of Finasteride. People discussed anecdotal experiences with Pyrilutamide as well as suggestions to wait out Phase 3 trials before making any conclusions.

community FOL005 claims it's better than Finasteride and Minoxidil.

in Technology 184 upvotes 1 year ago

FOL-005 claims to be more effective than Minoxidil and Finasteride but lacks anti-DHT properties, leading to potential reduced efficacy over time. Concerns are raised about misleading marketing and the safety of alternative treatments like Pyrilutamide and Clascoterone.

community Homemade pyri solution- problems

in Treatment 1 upvotes 2 years ago

A user mixed a pyrilutamide solution and noticed undissolved powder at the bottom, questioning if this is normal and how long to wait before applying it. They wished others good luck with their treatments.

community Pyrilutamide six month update photos

in Progress Pictures 13 upvotes 3 years ago

A six month update of the users' experience with Pyrilutamide, a hair loss treatment that combines Minoxidil, Finasteride and RU58841.

community Pyrilutamide or RU or cb-03-01?

in Minoxidil 2 upvotes 4 months ago

The conversation discusses using Minoxidil, finasteride, RU58841, and pyrilutamide for hair loss treatment. The user is considering adding a topical treatment and has not experienced side effects from current treatments.

community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

in Research/Science 58 upvotes 3 weeks ago

Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

community [Research] RU-58841/Pyrilutamide and impacts on male fertility

in Research/Science 5 upvotes 2 years ago

The drugs RU-58841, Pyrilutamide (KX-826), Apalutamide, Enzalutamide, and Darolutamide, which are nonsteroidal antiandrogens (NSAA), potentially impacting male fertility. Pyrilutamide, similar to Enzalutamide, may have reversible effects on fertility.

community pyrilutamide GB update please? Anything no matter how big or small

in Update 30 upvotes 3 years ago

The effects of Finasteride on hair loss and its side-effects, such as aching balls. The user has been taking it for two years with no changes to the symptom.

community What to take from the Actifolic?

in Finasteride/Dutasteride 1 upvotes 2 years ago

The user is considering starting Minoxidil and is looking for a topical solution to combine with it. They are confused about which product to prioritize among options like RU58841, Pyrilutamide, FinaTopic, and DutaTopic.