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      community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

      in Research/Science  60 upvotes 1 month ago
      Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

      community Progressi in 9 mesi, da luglio 2025 a marzo 2026

      in Progress Pictures  153 upvotes 1 month ago
      The user shared their 9-month hair regrowth progress using topical Minoxidil 5%, finasteride 0.05%, retinoic acid 0.01%, dermastamping, ketoconazole shampoo, and supplements like biotin. They experienced some hair density improvement but minimal change in the hairline, with initial side effects from finasteride that resolved after dosage adjustment.

      community Accrochez vous à votre traitement !

      in Finasteride/Dutasteride  6 upvotes 1 month ago
      The user resumed taking 5mg oral minoxidil and 0.5mg dutasteride daily, with vitamins, and noticed hair regrowth. They switched from finasteride to dutasteride due to side effects and prefer oral minoxidil over topical for convenience and effectiveness.

      community Why hasn’t anyone made a "DHT sponge" biologic yet???

      in Research/Science  45 upvotes 5 months ago
      The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.

      community 4 month update to my hair regrowth journey

      in Progress Pictures  74 upvotes 9 months ago
      The user shared a four-month update on their hair regrowth journey using 1mg daily finasteride, 5mg daily oral minoxidil, and weekly dermarolling, noting significant improvement in hair thickness and uniform growth. They reported no side effects from minoxidil except increased hair growth on arms, fingers, and eyelashes.

      community 1 year on Fin and Min. Diffuse thinner.

      in Is this regrowth?  18 upvotes 1 year ago
      The conversation is about a user experiencing hair loss who has been using finasteride for a year and minoxidil once a day for five months, but still experiences shedding and thin hair. The user is considering switching to dutasteride next year and shares their progress with others using similar treatments.

      community Shed 2 years into finasteride and minoxidil

      in Minoxidil  8 upvotes 1 year ago
      A user has been on finasteride for 1.5 years and minoxidil for 2 years, experiencing worsening hair shedding, losing 300+ hairs per wash. They are concerned if this indicates the medicine isn't working and are seeking others' experiences.

      community 50 years old 4.5 months on Fin

      in Finasteride/Dutasteride  28 upvotes 4 years ago
      A 50-year-old user shared their positive experience with hair regrowth using finasteride, minoxidil, biotin, pumpkin seed oil, derma rolling, biotin shampoo, and Nizoral. They reported significant improvement in hair density and regrowth, especially in the crown and mid-scalp areas, with no side effects.

      community Carrier for homemade topical Finasteride

      in Chat  5 upvotes 1 year ago
      The conversation is about making topical finasteride using stemoxydine as a carrier. The user is considering buying Redken Cerafill Hair Re-Densifying Treatment (Stemoxydine) 90ml for this purpose.

      community Leaving the fight. Got buzzed.

      in Shaved/buzzed  271 upvotes 2 years ago
      The conclusion of the conversation is that the user has decided to embrace their hair loss and has buzzed their head. They plan to continue their current hair loss treatments until they run out of stock. They also mention having dandruff and will continue medication for that.

      community Is there new research about pumpkin oil as a DHT blocker (2026)?

      in Research/Science  9 upvotes 5 days ago
      Pumpkin seed oil is considered a weak DHT blocker compared to finasteride and dutasteride, with some users reporting side effects like mood changes and reduced libido. Despite some anecdotal benefits for urinary issues, it is not effective for hair loss, and finasteride is preferred by some users for its lack of side effects.

      community 1 Year and Month (nearly) 1mg of only Fin daily

      in Progress Pictures  96 upvotes 3 weeks ago
      The conversation discusses hair loss treatment using finasteride, with the user noting improvements in hair density but a recent decrease in vertex density. Suggestions include adding minoxidil, but the user avoids it due to its toxicity to cats and considers oral minoxidil instead.

      community Update: going nuclear! (Switch to dut)

      in Update  13 upvotes 4 weeks ago
      The user had a hair transplant in March 2025 and has been using finasteride since 2023, which halted hair loss but didn't fully restore density. They plan to use dutasteride twice weekly, finasteride five times a week, and saw palmetto to improve hair thickness.

      community One Year Progress, keep the faith

      in Progress Pictures  286 upvotes 1 month ago
      The conversation is about a user's one-year progress in treating hair loss using a combination of finasteride and minoxidil spray, derma rolling, and Nizoral shampoo. The user reports significant improvement and increased confidence, while others offer advice and express admiration for the results.

      community 9-Month Routine Update. Advice?

      in Update  3 upvotes 1 month ago
      The user has been using 1mg Finasteride and 5% topical Minoxidil for 9 months with little improvement and has recently added microneedling, showing slight progress. The new protocol includes switching to 5mg oral Minoxidil, continuing microneedling, and adding Anagenil Complex, while seeking advice on whether to stop topical Minoxidil and the effectiveness of Anagenil Complex.

      community Turkey is constantly pouring money into fear mongering around finasteride in order to protect its hair transplant economy

      in Satire  116 upvotes 1 month ago
      Finasteride and minoxidil are commonly recommended by hair transplant clinics, including those in Turkey, despite some negative perceptions and concerns about side effects. The conversation highlights differing opinions on the effectiveness and safety of these treatments, with some users expressing skepticism about side effects and others emphasizing the importance of these medications for successful hair transplants.

      community Hair Loss “Cure” for Inflammation: Topical Roflumilast

      in Research/Science  32 upvotes 3 months ago
      Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

      community Hair Journey: Got great results from oral fin and topical min then switched to oral min, then back to topical min, then back to oral

      in Is this regrowth?  53 upvotes 4 months ago
      The user experienced significant hair regrowth using oral finasteride and topical minoxidil, but switching between oral and topical minoxidil led to hair loss and uncertainty about future treatment. They are considering sticking with oral minoxidil and finasteride, possibly adding dutasteride or opting for a hair transplant.