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690-720 / 1000+ resultscommunity Can aromatase inhibitors make dutasteride/finasteride useless?
The conversation discusses using aromatase inhibitors with dutasteride or finasteride for hair loss, which can prevent testosterone from turning into estrogen but may lead to increased DHT and potentially make finasteride less effective. There's concern about proper dosing and side effects like gynecomastia and emotional changes.
community Topical fin/minox + nizo shampoo and microneedling
The user is using topical finasteride, minoxidil, nizoral shampoo, and microneedling for hair regrowth but hasn't seen results after 2-3 weeks. They added tretinoin to their routine and are advised to wait a few months for potential changes.
community Sustaining minoxidil dependent hairs?
Minoxidil-dependent hairs fall out if minoxidil is stopped. New treatments like GT20029, FOL055, or TDM105795 might help sustain these hairs.
community If RU58841 is such an effective anti androgen
RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.
community Any positive experiences from homemade low dose (0.01%) topical fin? (Male, Age 18)
An 18-year-old male experienced positive results with oral finasteride but stopped due to side effects and is now trying homemade low-dose (0.01%) topical finasteride mixed with liquid minoxidil to manage hair loss. He seeks feedback on the effectiveness of this DIY topical treatment.
community Blocking dht should bring it back. So why does fin mostly just hold the line?
community TIL about Alfatradiol, a topical DHT blocker. Has anyone else ever heard or read about this? Or used it?
Hair loss treatments, including Alfatradiol, Minoxidil, Finasteride, and RU58841. It discusses the efficacy of these treatments for hair growth and regrowth.
community Can’t do finasteride. Does this automatically cross out Pyrilutamide?
Hair loss discussion includes finasteride intolerance and questioning if Pyrilutamide is an alternative. Pyrilutamide not commercially available, but may be tolerable if approved since it's not a 5aR inhibitor.
community The hardest hair protocol ever!
The user is using RU58841, finasteride, dutasteride, and minoxidil to slow down aggressive hair loss but is still experiencing hair shedding due to high testosterone levels. They plan to use ostarine to lower testosterone and prevent hair loss while maintaining muscle mass, and will continue using the other treatments.
community Laser Diode Cap, I already use Oral Fin, Topical Min 5%, Nizoral and Microneedling
The user is seeking advice on maximizing hair growth while using oral finasteride, topical minoxidil, Nizoral, and microneedling, and is considering adding a laser diode cap, topical finasteride, retinol, and caffeine. Suggestions include using tretinoin with minoxidil for better absorption, switching to dutasteride, and considering RU58841 or pyrilutamide.
community Rapid Minoxidil Response Test (TrichoGene) - anyone tried it?
A user tried the Rapid Minoxidil Response Test (TrichoGene) and found they don't respond to topical Minoxidil, so they added tretinoin. The test is available internationally, and another user is considering ordering it.
community Made an interesting observation today (caffeine, nicotine)
The user observed that stopping nicotine and caffeine improved their scalp health while using oral finasteride. However, relapsing with caffeine and nicotine caused scalp tightness and inflammation.
community Ru-58841 vs KX-826/pyrilutamide while on steroids
The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.
community Shiseido filed for this patent in May 2019. Let's get some big brain discussion on this.
The conversation discusses a patent filed by Shiseido for cloning Dermal Papilla (DP) cells to treat hair loss. The method involves using viral vectors to maintain the cells' growth-inducing properties, differing from Replicel's approach with Dermal Sheath Cup (DSC) cells.
community RU and cetosomal minoxidil topical
Mixing RU58841 with cetosomal minoxidil is discussed due to scalp irritation from ethanol PG vehicles. A mixture of the two turned bright pink when left to dry.
community Creating an all-in one topical. Dumb idea?
The user is considering combining finasteride and minoxidil tablets into a topical solution that already includes Garnier Fructis stemoxydine and CB0103. They are seeking advice on whether this combination is effective and safe.
community Does the HMI-115 actually have potential or is it another false hope?
Hair loss discussion includes potential HMI-115 treatment. Topical mucuna pruriens shows good results, blocking prolactin possibly more important than blocking DHT.
community Homemade fin - solubilization issue
The user is attempting to create a topical finasteride solution by mixing crushed finasteride pills with minoxidil but is facing solubility issues. They are unsure if the finasteride has dissolved properly and are seeking advice on whether it is safe to use and if there is a solution to the problem.
community Prepare to be disappointed by PP405
Delayed release oral minoxidil is seen as a promising advancement for hair loss treatment, offering safer, higher doses and more consistent hair follicle stimulation compared to current options. However, it is not expected to replace finasteride or dutasteride, as it does not prevent androgenetic alopecia.
community RU58841 Permanently Fixed Balding In Unexpected Way.
The user humorously describes trying various hair loss treatments, including minoxidil, finasteride, and RU58841, with a satirical twist involving psychedelic experiences and imaginary entities. They mistakenly used LSD instead of RU58841 and plan to continue experimenting with other substances.
community If PP405 goes systemic this would be quite catastrophic
Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.
community topical cetirizine to control scalp inflammation
The user applies a topical solution containing minoxidil, finasteride, dutasteride, retinoic acid, and hydrocortisone to address scalp inflammation and is considering adding cetirizine to the mix. They are calculating the correct amount of cetirizine to add to their formula and have paused this approach to retry oral minoxidil.
community Possible transgenerational effects of finasteride use on male offspring? (STUDY)
Finasteride may affect male offspring's fertility and hormonal balance, with debates on whether to discontinue use before conception. Some users report no issues, while others highlight the high doses used in rat studies.
community Debunk the debunk ? - Not sure but this study still exists ...
The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, and RU58841. It highlights a study suggesting that sulforaphane may reduce DHT levels and promote hair growth in mice.
community Pyrilutamide, the molecule's true nature - Research
The conversation discusses Pyrilutamide for hair loss, with skepticism about its legitimacy and mentions of an upcoming press release from Kintor. It also references ongoing trials and includes links for further information.
community Considering Quitting Topical Min
The user is considering stopping topical minoxidil due to lack of improvement in hair growth and is exploring alternatives like oral minoxidil, topical finasteride, and tretinoin. They are hesitant about oral finasteride and dutasteride, and are open to trying oral minoxidil if available, despite concerns about potential heart-related side effects.
community Topical rapamycin, metformin, a-kg grow hair
The conversation discusses the potential of topical rapamycin, metformin, and alpha-ketoglutarate (a-KG) for hair growth, with skepticism expressed about their effectiveness based on personal experience and existing use. It also mentions AICAR, known as cardarine or GW, which is not suitable for long-term use due to cancer risks in animal studies and its similarity to metformin.
community When will HMI-115 second trail be over?
A clinical trial for hair loss treatments involving Minoxidil, Finasteride, and RU58841, and when the results of the trial will be available.
community Using botox more effective than finasteride - and an argument against FUT
Botox injections may be more effective than finasteride for hair growth by reducing scalp tension. The discussion also suggests choosing FUE over FUT due to potential loss of scalp elasticity with FUT.