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      community Opinions on the “best” topical out there?

      in Treatment  1 upvotes 3 months ago
      The conversation is about choosing effective hair loss treatments, specifically discussing RU58841, 5% minoxidil, copper peptides, microneedling, finasteride, dutasteride, and Tretinoin. The user seeks advice on the best topical treatments and prefers to use only 1-2 products.

      community 5 months topical fin + min + tret hairline

      in Finasteride/Dutasteride  6 upvotes 1 year ago
      A 20-year-old male has been using a topical mix of finasteride, minoxidil, and tretinoin for five months without seeing significant hairline improvement. He is considering adding oral dutasteride or a hair transplant for better results.

      community Diffuse thinning is the worst. Nothing helps.

      in Update 5 months ago
      The user is experiencing diffuse thinning and has tried treatments like topical and oral finasteride, oral dutasteride, topical minoxidil, microneedling, melatonin, and caffeine without success. Despite using these treatments for over four years, the user reports continued hair thinning and is considering trying RU58841.

      community Topical fin/min/tret hairline worse after 15 months

      in Progress Pictures  3 upvotes 4 months ago
      The user has been using a combination spray with 0.1% finasteride, 5% minoxidil, and tretinoin for over a year but feels their hairline has worsened. They are considering increasing the concentration of finasteride and adding 5% minoxidil once a day, while another user suggests trying oral finasteride for potentially better results.

      community Scalp Biopsy Results - Almost 2 Years Dutasteride, Still Worsening

      in Update  24 upvotes 7 months ago
      Dutasteride and finasteride are not effectively stopping hair loss for some users, despite long-term use. Some are considering or using RU58841, pyrilutamide, and other treatments like microneedling, while also managing seborrheic dermatitis with diet and topical solutions.

      community Clascoterone - what we have right now

      in Research/Science  19 upvotes 1 month ago
      Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

      community Kintor develop GT20026 Anti-Androgen receptor drug with NO SIDES

      in Treatment  17 upvotes 5 years ago
      The conversation discusses GT20029, a new topical drug for hair loss and acne without notable side effects, which has been accepted for investigational use in China. Some users express skepticism about the legitimacy of the company and the potential for other drugs like RU58841 to be developed due to patent expiration and lack of profitability.

      community Dermarolling for Diffused Thinning.

      in Treatment  4 upvotes 7 years ago
      The user experienced noticeable hair growth after starting dermarolling with a 1mm device, using minoxidil, and nizoral shampoo. They plan to reduce dermarolling frequency to three times a week and are considering additional treatments like finasteride or a hair transplant for increased hair density.

      community Just had my first dermatologist appointment - unsure on Oral Minox vs Compounded Min/Fin/Tret (while already on Dut)

      in Minoxidil  2 upvotes 7 months ago
      A 28-year-old male, previously on dutasteride for hair loss, is considering oral minoxidil or a compounded treatment of minoxidil, finasteride, and tretinoin after noticing hairline recession. The dermatologist suggested oral minoxidil and mentioned a compounded option, but the user is unsure about its benefits compared to current treatments.

      community Minoxidil, microneedling and buying tretinoin from Germany

      in Minoxidil  1 upvotes 1 year ago
      The conversation discusses using minoxidil with microneedling and considering tretinoin to enhance hair growth, especially for those who are weak responders to minoxidil. It also explores the potential of using tazarotene, a stronger retinoid, to boost minoxidil's effectiveness and addresses purchasing tretinoin from Germany.

      community Tretinoin & Minoxidil application

      in Chat  6 upvotes 2 years ago
      Using Tretinoin with Minoxidil may increase Minoxidil's absorption and improve hair growth results. The user is seeking advice on how to apply both treatments effectively.

      community 22M Dut+min+microneedling. Diffuse AGA.

      in Progress Pictures  19 upvotes 1 month ago
      A 22-year-old male uses dutasteride, a serum with 10% minoxidil and 0.5% finasteride, and microneedling for diffuse androgenetic alopecia. Progress pictures show changes from July 2025 to February 2026.

      community What do you think about this topical formula?

      in Finasteride/Dutasteride  3 upvotes 1 year ago
      The conversation discusses a topical formula for hair loss including Finasteride (0.025%), Minoxidil (0.5%), Tretinoin (0.01%), Caffeine (0.005%), Melatonin (0.003%), Tea Tree Oil (0.05%), Aloe (0.05%), Biotin (0.05%), and Fagron TrichoXidil (2.5%). The user considers removing Minoxidil and Tretinoin to test TrichoXidil's effectiveness.

      community Ketoconazole mesotherapy plausible?

      in Ketoconazole  10 upvotes 1 year ago
      The conversation discusses using ketoconazole, an anti-androgen, for hair loss and whether mesotherapy with dermarolling could enhance its absorption into the scalp. The user questions if the typical 2% ketoconazole shampoo dose would be effective when used after dermarolling to target androgen receptors in the scalp.

      community Olumiant alternative for Alopecia Areata?

      in Treatment  1 upvotes 3 years ago
      A user with alopecia areata is considering treatment options like injections or Olumiant but is concerned about cost and whether delaying treatment will lead to permanent hair loss. They are seeking alternative treatments that are more affordable for a college student.

      community Any positive responses for Diffuse Thinner with Retrograde using Fin/Min/Dut

      in Finasteride/Dutasteride  4 upvotes 1 year ago
      People with diffuse thinning and retrograde hair loss are discussing treatments like finasteride, minoxidil, and dutasteride, with some reporting improvements and others experiencing issues like scalp inflammation and increased sebum. Suggestions include addressing scalp inflammation, considering gut health, and possibly using topical antiandrogens or micro-needling.

      community Feeling pretty hopeless... Dry skin and eczema causing my alopecia.

      in Chat  12 upvotes 2 years ago
      The user has been using dutasteride, lymecycline, betamethasone, and minoxidil for hair loss but struggles with eczema and dry skin. They feel hopeless as no treatments or moisturizers have helped, and they are concerned about their appearance due to their soft facial features.

      community 6 months difference on topical finasteride

      in Is this regrowth?  131 upvotes 1 year ago
      User shared 6-month progress using topical finasteride, biotin, and occasional dermarolling, reporting no side effects except possible depression. Replies praised the results and shared personal experiences with finasteride.

      community 12 months progress. Min Topical Fin Pyri MN

      in Progress Pictures  14 upvotes 1 year ago
      A user shared their 12-month progress using 0.5% Pyrilutamide once daily, 0.025% topical finasteride once daily, 5% Minoxidil twice daily, and microneedling 3 times a week. They reported good progress but noted a slowdown in recent months, hoping for thicker hair soon.

      community Does anybody else got their hair ruined when on tretinoin?

      in Chat  4 upvotes 1 year ago
      The user experienced hair shedding and follicle shrinkage when using retinoic acid, despite trying different concentrations and frequencies. The hair loss persisted for six months but regrew after stopping the treatment.

      community Minoxidil with Tretinoin together

      in Minoxidil  6 upvotes 9 months ago
      Combining tretinoin with minoxidil may improve absorption by exfoliating the scalp, but results vary. Users suggest starting with low frequency to avoid irritation, and some recommend additional treatments like finasteride or microneedling.