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      community The story of RU58841/PSK3841

      in Research/Science 1 year ago
      RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

      community Looking for the new RU58841 source in EU

      in Treatment  6 upvotes 2 years ago
      A user is seeking a new source for RU58841 in the EU after their previous supplier stopped selling it. They mention considering Anagen, Actifolic, Minoxidilmax, and rudirect, and are using a treatment mixing RU58841 with Stemoxydine and Alfatradiol.

      community Looking for the new RU58841 source in EU

      in Treatment  5 upvotes 2 years ago
      A user is seeking a new source for RU58841 in the EU after their previous supplier stopped selling it. They mention considering Anagen, Actifolic, Minoxidilmax, and rudirect, and are using a treatment mixing RU58841 with Stemoxydine and Alfatradiol.

      community Mix Pyrilutamide powder in Minoxidil solution?

      in Minoxidil  3 upvotes 2 years ago
      Mixing Pyrilutamide powder with Minoxidil solution is being considered. The Minoxidil solution contains Minoxidil 5%, Azelaic acid 5%, ABN complex 0.8%, Retinol 0.025%, Caffeine 0.001%, and a delivery vehicle.

      community Minox 5 Months + Finasterid 3 Months

      in Progress Pictures  384 upvotes 1 year ago
      The user has been using topical minoxidil for 5 months and oral finasteride for 3 months, reporting positive results without side effects. They apply minoxidil twice daily and take 1 mg of finasteride daily.

      community PP405 2a study was a safety study. Some rational explaining.

      in Research/Science  22 upvotes 9 months ago
      The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.

      community Prepare to be disappointed by PP405

      in Research/Science  23 upvotes 4 months ago
      Delayed release oral minoxidil is seen as a promising advancement for hair loss treatment, offering safer, higher doses and more consistent hair follicle stimulation compared to current options. However, it is not expected to replace finasteride or dutasteride, as it does not prevent androgenetic alopecia.

      community Fluridil (Eucapil) seems like a great option?

      in Treatment  4 upvotes 6 months ago
      The user stopped using finasteride due to side effects and is considering Fluridil (Eucapil) as an alternative for hair loss treatment. They are exploring other options like RU58841 and are interested in the experiences of others with Fluridil, noting its good safety profile despite the cost.

      community 0.25 alfatradiol or 0.5 Pyrulitamide ?

      in Product  4 upvotes 7 months ago
      The conversation is about choosing an anti-androgen for hair loss treatment, with options being alfatradiol and pyrilutamide. Alfatradiol is considered a better choice due to its established use, while pyrilutamide is more experimental.

      community How long do you keep ru-58841 on?

      in Product  1 upvotes 8 months ago
      The conversation discusses the application of RU58841 for hair loss, with the user applying 1.75 mg at 5% concentration for half an hour daily. The user mentions managing seborrheic dermatitis while using this treatment.

      community 8 mo fin, 2mo min, 2mo vitamin D

      in Progress Pictures  45 upvotes 2 years ago
      A user shared progress pictures after 8 months of finasteride, 2 months of minoxidil, and 2 months of vitamin D. The post shows significant hair improvement despite some light differences in the photos.

      community Best homemade topical Finasteride formula ?

      in Treatment  3 upvotes 3 years ago
      The conversation discusses homemade topical finasteride formulas, comparing two solutions with different proportions of alcohol and propylene glycol. The user seeks advice on which formula is gentler on the scalp, suggesting that less alcohol might be better.

      community Vertoporfin research update by Dr Bloxham

      in Research/Science  71 upvotes 2 years ago
      The conversation discusses the potential of verteporfin in treating hair loss, with some users reporting positive results and speculating that it could lead to a cure for baldness. Others are skeptical, and there's a debate on the effectiveness of verteporfin for regrowing hair and reducing transplant scars.

      community Alright so FDA better approve PP405 as fast as they approved covid vaccine

      in Product  128 upvotes 10 months ago
      PP405 is a potential hair loss treatment showing promising early results, with hopes for market release by 2028, but skepticism remains due to inconclusive data and past disappointments with similar products. Current treatments like Minoxidil and Finasteride have side effects, leading some to anticipate PP405 as a safer alternative, though its effectiveness compared to placebo is debated.

      community Anybody used Fluridil ? Is my last hope.

      in Finasteride/Dutasteride  4 upvotes 3 years ago
      The conversation is about alternatives to finasteride for hair loss, with suggestions including fluridil, oral minoxidil, alfatradiol, and cb-03-01. Concerns about finasteride's side effects, including potential breast cancer risk, are also discussed.

      community 3 month of profess with fin and minoxidil

      in Progress Pictures  123 upvotes 2 years ago
      The conversation discusses a user's three-month progress using topical finasteride once a day, 6% minoxidil at night, and weekly dermastamping at 1.25mm for hair loss. Commenters note the impressive results and discuss application methods and safety precautions for family members.

      community formula 82D for diffuse androgenic alopecia (DUPA)

      in Is this regrowth?  16 upvotes 1 year ago
      The user is experiencing diffuse androgenic alopecia and is trying various treatments, including 5mg finasteride, loniten, and Formula 82D, which contains dutasteride, a steroid, and tretinoin. They report potential regrowth with Formula 82D, despite previous treatments being ineffective.

      community Recommend stemoxydine as an adjunct therapy

      in Treatment  4 upvotes 2 years ago
      The user has been using finasteride, minoxidil, retinoid, and occasional microneedling for hair loss with good results. They recently added stemoxydine, which improved their hair further, and suggest trying it, especially in the EU where it's easily available.

      community 45 years old - 4 months topical fin / min

      in Progress Pictures  114 upvotes 1 year ago
      A 45-year-old user shared progress pictures after 4 months of using a topical gel with 2.5% finasteride and 5% minoxidil once daily. The second picture shows significant improvement in hair growth.