Lab-grown hair using iPSCs is being explored, but practical applications are limited. Finasteride is suggested as the only current effective treatment.
Finasteride is being discussed as a significant treatment for male baldness, with some users sharing positive experiences and increased confidence, while others express concerns about potential side effects like loss of libido and erectile dysfunction. The conversation highlights differing opinions on the drug's impact and the broader societal implications of changing beauty standards.
A 24-year-old is using 5% topical minoxidil once daily, 1mg finasteride daily, and a derma stamp weekly for hair thickening. Users advise patience, caution with the derma stamp, and suggest waiting longer to see significant results.
A peptide-based delivery system for finasteride shows promise in reducing systemic side effects while maintaining hair growth effectiveness. Combining this with other treatments like minoxidil and RU58841 could enhance results with lower systemic absorption.
The conversation suggests that abstaining from ejaculation for a few months may help stop or reverse hair loss by potentially increasing testosterone and reducing DHT levels. It also mentions the use of minoxidil and finasteride as effective treatments for maintaining hair after a hair transplant.
A 23-year-old is using 2.5 mg dutasteride, 5 mg oral minoxidil, RU58841, a laser cap, and PRF injections for hair loss. They are hesitant about microneedling due to concerns about RU58841 absorption and are considering other treatments.
The conversation is about using ketoconazole shampoo for hair loss. Users suggest using it 2-3 times a week alongside other treatments like minoxidil and finasteride.
Hair loss requires proper diagnosis as it can have various causes, and treatments like finasteride, minoxidil, and dutasteride are often used. Many people express frustration with dermatologists and turn to self-research and alternative sources for treatment.
The user experienced positive hair regrowth after 4-5 months using oral minoxidil (10mg) and finasteride (1mg) without side effects. Concerns were raised about the high dosage of minoxidil and potential long-term health risks.
High prolactin levels may contribute to hair loss, and some users suggest supplements like mucuna pruriens, vitamin B6, vitamin E, L-Tyrosine, L-Theanine, DIM, and Zinc to lower prolactin. Lifestyle changes to increase dopamine, such as reducing screen time and stress, are also recommended.
The user is experiencing a receding hairline and is considering treatments. They are seeking advice on whether to use finasteride, minoxidil, or both for hair preservation and potential regrowth.
A 27-year-old actor shared his positive experience with two hair transplant surgeries, highlighting the importance of customization and detail for a natural look. He is taking finasteride to prevent future hair loss.
A 35-year-old man underwent a hair transplant with Dr. Patty at HairTran Clinic in Bangkok, receiving 4,037 grafts primarily for his crown area. The procedure cost 188,700 THB, with an additional 12,000 THB for optional PRP treatment, and he plans to update with progress pictures in a year.
Some people have side effects from finasteride and dutasteride due to hormonal predisposition, especially if DHT dominant. Alternatives like RU58841, Pyrilutamide, and Breezula are suggested to target scalp androgen receptors without altering overall hormones.
The user stopped using finasteride due to side effects and is considering Fluridil (Eucapil) as an alternative for hair loss treatment. They are exploring other options like RU58841 and are interested in the experiences of others with Fluridil, noting its good safety profile despite the cost.
The user has been using minoxidil on their hairline for about six months and is also on finasteride. They are considering applying minoxidil to the rest of their scalp to improve hair density but are concerned about potential shedding.
Ketoconazole shampoo is primarily used to reduce scalp fungus and inflammation, not to block DHT or androgen receptors. It may help with seborrheic dermatitis and improve scalp health, but its effects on hair loss are minimal compared to treatments like finasteride.
The user feels discouraged after three months of microneedling with no visible hair regrowth, despite using 5% topical minoxidil and 200mg of spironolactone. Others suggest waiting 12 months for results, checking vitamin D levels, and considering tretinoin or tazarotene cream instead of microneedling.
Using tretinoin or tazarotene with minoxidil may eliminate the need for microneedling or dermastamping. Microneedling can enhance minoxidil's effects but may cause long-term scalp issues.
Dutasteride is more effective than finasteride for hair loss, with optimal dosing at 0.5mg once or twice a week to minimize side effects. Topical application may further reduce side effects while effectively lowering scalp DHT.
Fatty acid metabolic signaling can activate epithelial stem cells for hair regeneration. Oleic and palmitoleic acids showed the best results, but practical application on humans remains uncertain.
A user is concerned about low testosterone while using finasteride 0.625mg MWF and considers ashwagandha for stress. Others suggest exercise, magnesium, and not worrying about testosterone levels if no significant side effects are felt.
The user experienced scalp irritation from a Finasteride and Minoxidil spray and serum. They are considering switching to foam, oral treatments, or another provider.
A 21-year-old male has been experiencing persistent hair loss despite using treatments like dutasteride, finasteride, RU58841, minoxidil, and ketoconazole. Suggestions include checking for hormonal issues, nutritional deficiencies, or allergies, and consulting a doctor for professional advice.
Hair loss is influenced by scalp tension, stress, and environmental factors, not just hormones. Treatments like tretinoin, microneedling, scalp massage, and Botox can reduce tension and improve hair health.
Hair loss is less common now due to accessible treatments like finasteride, minoxidil, and hair transplants. Improved hair care, skincare, and lifestyle changes contribute to people looking younger today.
Tretinoin may enhance minoxidil absorption, potentially improving hair regrowth when combined with microneedling. Users discuss various treatments like minoxidil, finasteride, dutasteride, and microneedling, with mixed results and concerns about side effects and scarring.
Dutasteride significantly reduces DHT levels in hair follicles, potentially more effectively than previously thought. The discussion highlights differences in DHT measurements and the impact on hair loss treatment.
Hair loss is likely due to male pattern baldness, not vitamin D deficiency. Taking 60k vitamin D tablets weekly is not recommended; 2k per day is sufficient.
PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.