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      community A little perspective from Bill Burr

       6 upvotes 12 years ago
      The user has been using Propecia for about 11 months and believes it has slowed hair loss. They acknowledge likely future hair loss and emphasize the value of a positive attitude.

      community Pili migrans? Lichen something? Seb derm?

      in Female  19 upvotes 1 year ago
      The conversation is about a female experiencing hair loss and seeking advice on why it's difficult to regrow hair. Specific treatments like Minoxidil, finasteride, or RU58841 are not mentioned.

      community About 3 months into RU58841 and sulforaphane

      in Update  5 upvotes 4 years ago
      The user experienced almost no improvement in hair loss after 3 months using microneedling, RU58841, sulforaphane, finasteride, and dutasteride, especially after stopping minoxidil. They believe minoxidil is more effective than RU58841.

      community 2 years on finasteride - holding steady, but not much regrowth

      in Progress Pictures  76 upvotes 6 days ago
      The user has been on finasteride for two years, experiencing maintenance of hair without significant regrowth, and is considering adding minoxidil for potential improvement. They are generally satisfied with the results and are exploring other options like peptides and possibly a hair transplant in the future.

      community Clascoterone 12 months phase 3 result out

      in Treatment  37 upvotes 1 week ago
      Clascoterone is promising for hair loss, showing 24.5% improvement in satisfaction compared to placebo. Users consider it an alternative to finasteride, with concerns about absorption and side effects.

      community Why is nobody talking about topical Spironolactone?

      in Chat  11 upvotes 2 weeks ago
      Topical spironolactone is discussed as a hair loss treatment, with concerns about its effectiveness and side effects compared to finasteride and minoxidil. Users mention its unpleasant smell, potential systemic absorption, and suggest alternatives like pyrilutamide and alfatradiol.

      community Clascoterone/ Breezula will it work

      in Research/Science 2 weeks ago
      Breezula's effectiveness is uncertain, with some users skeptical about its potential and others noting its recent availability on the grey market. A user reported success with a stack of Dutasteride (oral), Minoxidil (topical), and RU58841 (topical), achieving significant hair improvement after 18 months.

      community Saw an opinion on PP405 and sharing

      in Technology 3 weeks ago
      PP405 is discussed as a potential adjunct therapy for hair loss, with skepticism about its effectiveness and trial results. Users mention combining it with finasteride and minoxidil for better results, while others debate the root causes of hair loss and the limitations of current treatments.

      community Welp - pp405 conference showed nothing

      in Update  79 upvotes 3 weeks ago
      PP405 shows potential for hair growth by increasing terminal hair and converting vellus hairs, but results are modest and more waiting is needed. It complements existing treatments like minoxidil and finasteride, but won't replace them.

      community By when would pp405 be available in the grey market?

      in Chat  15 upvotes 4 weeks ago
      PP405 might take 3-4 years to be available, but some claim Everychem offers a similar product, though its effectiveness is debated. Users discuss the risks of using untested grey market products and the potential for adverse effects.

      community Clascoterone - what we have right now

      in Research/Science  20 upvotes 2 months ago
      Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

      community Prepare to be disappointed by PP405

      in Research/Science  23 upvotes 2 months ago
      Delayed release oral minoxidil is seen as a promising advancement for hair loss treatment, offering safer, higher doses and more consistent hair follicle stimulation compared to current options. However, it is not expected to replace finasteride or dutasteride, as it does not prevent androgenetic alopecia.

      community My progress after 4-5 months of taking meds

      in Progress Pictures  411 upvotes 2 months ago
      The user experienced positive hair regrowth after 4-5 months using oral minoxidil (10mg) and finasteride (1mg) without side effects. Concerns were raised about the high dosage of minoxidil and potential long-term health risks.

      community Occipitalis Muscle Tension Theory

      in Treatment  9 upvotes 2 months ago
      Scalp tension from the occipitalis muscle is theorized to contribute to hair loss, but most believe DHT and genetics are the main causes. Treatments like finasteride and minoxidil are considered more effective than addressing scalp tension.

      community DNA test result is incredible !

      in Technology  31 upvotes 2 months ago
      The conversation discusses a personalized hair loss treatment plan based on DNA test results, recommending Minoxidil, Dutasteride, 17-alpha Estradiol, Cetirizine, and PRP sessions. The test identifies a high risk of hair loss due to DHT but a good response to Minoxidil, suggesting a tailored approach to treatment.

      community PP405 is NOT gray market jxl069

      in Technology  26 upvotes 3 months ago
      PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

      community Using RU58841 instead of finasteride.

      in Treatment  2 upvotes 3 months ago
      The user stopped using finasteride due to side effects and switched to RU58841, which seems to be working for hair regrowth. They are considering RU58841 and minoxidil as long-term treatments, while others discuss the safety and effectiveness of these options.
      Can liver problems be associated with response to the oral minoxidil?

      community Can liver problems be associated with response to the oral minoxidil?

      in Research  147 upvotes 3 months ago
      Liver problems may reduce the effectiveness of oral minoxidil due to impaired SULT1A1 enzyme activity, which is crucial for converting minoxidil to its active form. This reduction in enzyme function can significantly decrease the drug's effectiveness in promoting hair growth.

      community I had claude create a protocol only using fda approved drugs.

      in Research/Science  2 upvotes 3 months ago
      A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.

      community Topical Vitamin C trials for hair loss?

      in Treatment  7 upvotes 3 months ago
      Topical high-dose vitamin C is discussed as a potential treatment for hair loss due to its ability to inhibit DHT and reduce histamine. Some users express skepticism about its effectiveness compared to treatments like finasteride.

      community What do you guys think of stem cell hai restoration?

      in Chat  9 upvotes 4 months ago
      Stem cell hair restoration lacks scientific evidence and is often considered a scam. Effective hair loss treatments include hair transplants, Minoxidil, and Finasteride, but stem cell treatments are not proven.