Search

for
Search:

Did you mean Melanocortin 1 Receptor?

GlossaryMelanocortin 1 Receptor

regulates melanin production, affecting hair and skin color

The Melanocortin 1 Receptor (MC1R) is a protein found on the surface of melanocytes, the cells responsible for producing melanin, the pigment that gives skin, hair, and eyes their color. Variations in the MC1R gene can influence hair color, skin tone, and susceptibility to UV radiation, and are also associated with red hair and fair skin.

Related Terms

Sort by

Community Join

30 / 1000+ results

community My experiences from 4 days of topical melatonin applied twice daily.

in Product 6 upvotes 3 years ago

The user is trying topical melatonin for hair loss and reports feeling tired and unmotivated, considering using it only at night due to restlessness. No hair regrowth noticed after 4 days.

community 4 months after adding topical finasteride + melatonin, and switching from dermaroller to dr. Pen

in Treatment 222 upvotes 3 years ago

A user's experience using topical finasteride and melatonin to regrow hair, as well as their use of dermaroller versus dr. Pen for microneedling. People discussed the benefits of oral minoxidil and questioned if melatonin could help with hair regrowth.

community Results with latanoprost/melatonin?

in Treatment 10 upvotes 4 years ago

Hair loss discussion includes topical latanoprost and melatonin. Users share regimens and products used for treatment.

community Any topical melatonin users here ?

in Treatment 4 upvotes 3 years ago

The conversation discusses using topical melatonin for diffuse thinning and mentions treatments like Minoxidil, finasteride, and RU58841. The user is seeking advice on whether melatonin could help with their condition.

community Anyone had luck with one of those minoxidil + tretinoin + caffeine + melatonin sprays?

in Minoxidil 2 upvotes 1 year ago

The conversation discusses using a 4-in-1 spray containing minoxidil, tretinoin, caffeine, and melatonin for hair loss. Users consider the potential benefits of combining these ingredients, with some interest in a comprehensive approach to treatment.

community Since there is so much hype for cosmeRNA and HMI-115...

in Chat 46 upvotes 3 years ago

Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.

community Anyone experimenting with Melatonin?

in Treatment 4 upvotes 4 years ago

Melatonin is being explored as a hair loss treatment, with one user mixing it into minoxidil but not seeing results. The conversation discusses experimenting with melatonin concentrations.

community Has anyone tried latanoprost+microneedle?

in Microneedling 2 upvotes 2 years ago

Microneedling combined with latanoprost may convert vellus hairs to transitional or terminal hairs. The user suggests using oral minoxidil to increase vellus hair, then applying a high concentration of latanoprost with microneedling for conversion.

community Has anyone tried microneedling with topical melatonin, copper peptides, reservatrol+fisetin, or stemoxydine?

in Treatment 3 upvotes 1 year ago

The user is seeking alternatives to Minoxidil due to heart issues and is considering microneedling with topical melatonin, copper peptides, resveratrol+fisetin, or stemoxydine, which reportedly have minimal side effects. They are asking for information on the effectiveness of these treatments.

community Optimal dose for topical Melatonin

in Treatment 6 upvotes 2 years ago

The conversation is about finding the optimal concentration of topical melatonin for hair loss treatment. The user is considering making their own solution and is unsure whether a higher concentration is more effective for deactivating prolactin receptors.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 3 years ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Melatonin emerging as new treatment for androgenic alopecia?

in Update 35 upvotes 1 year ago

Melatonin is being considered as a potential treatment for androgenic alopecia, with some users discussing its effects and combining it with other treatments like minoxidil and finasteride. Concerns about melatonin's impact on hormones and side effects from other treatments like ketoconazole were also discussed.

community microinflammation caused by mometasone furoate?

in Research/Science 2 upvotes 3 years ago

The user experienced microinflammation on the crown after using mometasone furoate (Nasonex) nasal spray. They are seeking information on the relationship between this corticosteroid and hair loss.

community Effect of melatonin on aromatase expression

in Update 5 upvotes 3 years ago

Melatonin's effect on aromatase expression is unclear, with studies showing both increases and decreases. Hormonal impacts are complex and inconsistent, similar to changing health advice on other substances.

community Patent for topical resveratrol and melatonin for AGA

5 upvotes 6 years ago

The conversation discusses a patent for using topical resveratrol and melatonin to treat androgenetic alopecia (AGA) and also mentions interest in topical sulforaphane as a treatment.

community Anybody using topical melatonin in your stack? How is it working?

in Minoxidil 9 upvotes 3 years ago

The conversation discusses using topical melatonin as a treatment for hair loss, with one person considering adding it to their minoxidil solution and another sharing their experience of no hair shedding, possibly due to melatonin.

community Anyone try the 4 in 1 Spray w/ Minoxidil 5%, Caffeine .2%, Melatonin .1%, Tretinoin .01% (81 G)?

in Minoxidil 1 upvotes 4 months ago

The conversation is about a user considering switching to a 4 in 1 spray containing Minoxidil, Caffeine, Melatonin, and Tretinoin for hair loss after using a finasteride and minoxidil spray. The user recently switched to oral finasteride and is contemplating whether to continue using the remaining finasteride and minoxidil spray.

community 5ar alpha reductase stimulation is different depending on whether it’s type 1 or 2

in Hair Systems 16 upvotes 2 years ago

The conversation discusses how different factors can stimulate type 1 and type 2 isoforms of 5-alpha reductase, which are enzymes linked to hair loss. Specific treatments mentioned include oral Dutasteride and topical Finasteride.

community 4 months minox + fin +microneedling

in Progress Pictures 331 upvotes 3 years ago

A user's progress with treating hair loss, using minoxidil, finasteride and microneedling. The user experienced impressive results after four months of treatment, and mentioned that stopping recreational drugs and losing weight helped their hair regrowth.

community Latanoprost- an effective medication

in Treatment 6 upvotes 2 months ago

Latanoprost is discussed as a potential hair loss treatment, noted for its synergy with minoxidil and 5-AR inhibitors, but concerns include its effectiveness on scalp hair, cost, and potential skin darkening. Some users express interest in trying latanoprost or bimatoprost despite limited real-world evidence.

community 4 months into min/fin topical spray with 1-2x week microneedling

in Is this regrowth? 30 upvotes 1 year ago

The user is experiencing potential hair regrowth after 4 months of using a minoxidil and finasteride topical spray combined with microneedling 1-2 times a week. They notice some scalp redness and irritation but are unsure if the increased hair density is due to regrowth or longer hair.

community Anyone tried topical melatonin?

in Treatment 4 upvotes 1 year ago

The conversation is about using topical melatonin for hair retention and its potential effectiveness alongside minoxidil. The user explicitly does not want advice about finasteride.

community How long have you tried topical melatonin?

in Treatment 4 upvotes 2 years ago

The conversation is about the effectiveness of topical melatonin for hair loss, asking for details on dosage, frequency, duration of use, results, and brand information. An update includes a skeptical view on the studies regarding melatonin's effectiveness.

community Finally got hold of 0.1% latanoprost

in Treatment 6 upvotes 1 month ago

The conversation is about a user obtaining a compounded treatment for hair loss, including 0.1% latanoprost, 0.2% melatonin, and 1% cetirizine. The user also uses 2.5 mg dutasteride, 5 mg minoxidil, and RU58841 daily, and is at Norwood 2.

community Topical melatonin/oral

in Research/Science 12 upvotes 5 years ago

The conversation discusses the potential positive effects of melatonin on hair growth. The original poster plans to try both oral and topical melatonin and is seeking recommendations for a good source.

community Has anyone tried Topical Melatonin and had any results?

in Treatment 5 upvotes 3 years ago

The conversation is about using topical melatonin for hair loss treatment. Users discuss their experiences and results with topical melatonin, Minoxidil, finasteride, and RU58841.

community [Update ] 4 month progress 0.5mg fin, 6 months microneedling + nizoral + topical melatonin

in Update 4 upvotes 1 year ago

The user reported 4 months of using 0.5mg finasteride and 6 months of microneedling, Nizoral, and topical melatonin. They saw improvement on the left side but no improvement on the right side and are hesitant to start minoxidil.

community Galenic lotion. Science behind the components

in Treatment 1 upvotes 9 months ago

A user is considering a hair loss treatment lotion containing minoxidil, adenosine, caffeine, melatonin, and azelaic acid, questioning the interaction between caffeine and adenosine receptors. Another user suggests adding a topical anti-DHT ingredient like spironolactone, noting it should not be taken orally by men.

community EU topical melatonin recommendations?

in Treatment 6 upvotes 4 months ago

The conversation discusses recommendations for using topical melatonin for hair loss treatment. It also mentions Minoxidil, finasteride, and RU58841 as other treatments.

community A vehicle for powdered melatonin

in Treatment 6 upvotes 4 years ago

The conversation is about using topical melatonin for hair loss and seeking advice on a safe mixing solution or pre-mixed product. Specific treatments mentioned are minoxidil, finasteride, and RU58841.