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      community Estimate of GT20029 on the grey market?

      in Technology  9 upvotes 2 years ago
      The conversation is about when GT20029, a hair loss treatment, might be available on the grey market, with users discussing the challenges of compounding it and speculating it might be available after phase 2 results, similar to pyri. Specific treatments mentioned are pyri, RU58841, and GT20029.

      community Can absorption be intervened by oil, sebum etc?

      in Treatment  3 upvotes 1 year ago
      The conversation discusses whether oily scalp and sebum can hinder the absorption of topical hair loss treatments like Minoxidil and Finasteride, even when using tretinoin. The user is skeptical about the effectiveness of these treatments due to their oily scalp condition.

      community Dry and flaky scalp after starting Minoxidil+Tretinoin treatment.

      in Chat  6 upvotes 2 years ago
      A user reports a dry and flaky scalp after starting treatment with 5% minoxidil and 0.05% tretinoin, and is seeking advice on using olive oil or face moisturizer on the scalp. They also take finasteride and have tried microneedling, and are asking for the best time to moisturize after applying minoxidil.

      community Additional supplements / peptides to maximize finasteride benefit

      in Research/Science  3 upvotes 3 weeks ago
      The user is using finasteride, HGH, GHK-CU, BPC-157, KPV, biotin/collagen/keratin vitamins, ketoconazole shampoo, and low-dose naltrexone to address hair loss, avoiding minoxidil due to past shedding experiences. Adenosine is discussed as a potential alternative to minoxidil, though it is noted to be expensive and hard to find.

      community Topical fin 0.025%, min 5% - 2,5 months progress

      in Finasteride/Dutasteride  9 upvotes 1 year ago
      The user started using topical finasteride 0.025% and minoxidil 5% twice daily, seeing initial improvement but later experiencing shedding and scalp pain. They are considering increasing the finasteride dose to 0.05% while using keto shampoo and dermarolling, and are debating the effectiveness of low versus standard doses of finasteride.

      community Breezula is a good alternative

      in Research/Science  5 upvotes 1 month ago
      Clascoterone 5% solution (Breezula) is a promising alternative for androgenetic alopecia, showing continued hair growth with consistent use and no significant side effects. It may be suitable for those who cannot tolerate finasteride or dutasteride, especially when trying to conceive.

      community Where do you guys get Topilutamide from? (if you even do)

      in Chat  4 upvotes 1 month ago
      The conversation discusses sourcing Topilutamide (fluridil) as a treatment for hair loss, with users comparing it to RU58841 and finasteride. Users share their experiences with various treatments, including testosterone, DHT gel, and Proviron, while expressing difficulty in finding Topilutamide.

      community 2.5mg to 5mg OM after 2 weeks too soon?

      in Minoxidil  2 upvotes 2 years ago
      A user started taking 2.5mg oral Minoxidil (OM) and 1mg Finasteride after using topical Finasteride, Minoxidil, and Tretinoin for 2.5 months. They are considering increasing the OM dose before an upcoming hair transplant to improve its success.

      community Hims topical min/fin spray vs serum

      in Treatment  10 upvotes 2 years ago
      The conversation is about someone switching from a hair loss treatment spray with alcohol and propylene glycol to a serum with essential oils, questioning the absorption and effectiveness of the new product. The spray and serum both contain 0.3% finasteride and 6% minoxidil.

      community Clascoterone ph3 results ready

      in Research/Science  9 upvotes 6 months ago
      Clascoterone 5% solution showed a 539% improvement in hair count compared to placebo, but the actual increase in hair growth is minimal. Users express skepticism about the effectiveness of hair loss treatments.

      community My Pyrilutamide Experience so far

      in Update  78 upvotes 3 years ago
      A user's experience with Pyrilutamide for hair loss, which has been successful in reversing receding hairline when part of their stack with other treatments such as Dutasteride, Minoxidil, and Ketoconazole shampoo.

      community I’m taking Veradermics VDPHL01 - AMA

      in Treatment  174 upvotes 1 month ago
      A participant using Veradermics VDPHL01, an extended-release oral minoxidil, experienced significant hair regrowth from Norwood 6 to Norwood 3V without side effects. They plan to use dutasteride after the treatment to maintain results.

      community Feeling pretty hopeless... Dry skin and eczema causing my alopecia.

      in Chat  12 upvotes 2 years ago
      The user has been using dutasteride, lymecycline, betamethasone, and minoxidil for hair loss but struggles with eczema and dry skin. They feel hopeless as no treatments or moisturizers have helped, and they are concerned about their appearance due to their soft facial features.

      community Oral minoxidil vs Topical Minoxidil w/ Retinoic acid

      in Minoxidil  6 upvotes 10 months ago
      Topical minoxidil with retinoic acid is effective but causes scalp irritation, leading the user to consider switching to 2.5mg oral minoxidil. Oral minoxidil may cause body hair growth and heart-related side effects, so it's advised to use it under medical guidance.

      community For those that have used anti androgens what is your experience?

      in Research/Science  16 upvotes 2 years ago
      People discussed their experiences with anti-androgens for hair loss, mentioning side effects like chest pains with RU58841 and skepticism due to lack of safety data, while considering Fluridil as a potential addition to treatment. Some users expressed reluctance to use these chemicals.

      community Stacking Fluridil / Topilutamide with other + aqueous topicals?

      in Technology  1 upvotes 1 year ago
      The conversation discusses how to use fluridil/topilutamide with other hair loss treatments like liquid minoxidil and CB-03-01, considering fluridil's hydrophobic nature and potential degradation with water. The user questions the necessity of washing hair only once per week as suggested by the manufacturer.

      community Liquid minoxidil + pyrilutamide

      in Treatment  17 upvotes 3 years ago
      Potential treatments for hair loss, specifically the combination of liquid minoxidil and pyrilutamide, with some suggesting that adding finasteride may be beneficial.

      community PP405 - hair stem cell stimulation

      in Research/Science  53 upvotes 2 years ago
      PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 1 year ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community Topical Finasteride strength discussion

      in Research/Science  65 upvotes 2 years ago
      The conversation discusses the effectiveness of different concentrations and dosages of topical finasteride on scalp and serum DHT levels, comparing it to oral finasteride and noting the side effects seem to be fewer at lower dosages. Participants shared experiences and referenced a chart indicating similar scalp DHT reduction with 0.025% topical finasteride as with 1mg oral finasteride, but with fewer side effects.