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540-570 / 1000+ resultscommunity 11-month update. This time wet hair comparison!
The post discusses an 11-month hair loss treatment journey using dutasteride, minoxidil, nizoral, and 1.5mm derma rolling. The responses inquire about the frequency of derma rolling and express optimism for further progress.
community redensyl - follicle stem cell activator any experiences?
A Swiss product called Redensyl, which is supposed to target hair follicle stem cells and has recently been marketed in Europe. The post inquires if anyone has had any experience with the product.
community What to do when dut and min fail you?
The user is experiencing hair loss despite using minoxidil and dutasteride consistently since October, with no significant improvement. Suggestions include trying microneedling, switching dutasteride brands, or adding finasteride.
community 1 year progress update, dut+min
A 35-year-old shared their 1-year hair loss treatment progress using 0.5mg Dutasteride, 5mg oral Minoxidil, topical Minoxidil, and Ducray Anaphase+ shampoo daily, noting significant changes after 4 months despite some shedding. They reported minor side effects and followed their dermatologist's advice for the treatment plan.
community 14 months on Fin, Total T 899, serum DHT 276 — high total T may still drive scalp DHT even when blood levels look controlled
A 23-year-old male has been using finasteride and topical minoxidil for 14 months with slight improvement, but recent shedding led him to switch to a new minoxidil formulation without success. He is considering using topical RU58841 or dutasteride to better address scalp DHT, as his bloodwork shows high total testosterone and mid-range DHT levels.
community Is this the 2026 Hairloss Nuclear Stack?
A user discusses their extensive hair loss treatment regimen, which includes dutasteride, oral and topical minoxidil, RU58841, various supplements, and lifestyle changes. The conversation includes opinions on the effectiveness and necessity of such a comprehensive approach, with some users suggesting alternatives like microneedling and questioning the high dosage of dutasteride.
community DUT .5mg 1 YEAR & ORAL MIN 5mg
The user experienced no significant improvement in hair loss despite using Dutasteride, oral Minoxidil, and previously RU58841, and is uncertain if changes in medication or stopping RU58841 worsened the condition. Some users noted no change or slight improvement, while others suggested the possibility of Dutasteride causing issues.
community Let's discuss experimental - RU58841, Dutasteride, and Others
Discussing and researching different treatments for hair loss, including RU58841, Dutasteride, Spironolactone, Retin-A, Stemoxydine (Neogenic), Copper peptides, Superoxide Dismutase, NANO, and Eucapil.
community 14 Months on Dutasteride & Minoxidil, Seeking Advice to Improve Hairline Without Transplant
The user is seeking advice on improving their hairline, currently using dutasteride 0.5mg/day and oral minoxidil 5mg/day for 14 months. They want to avoid a hair transplant and are concerned about thin hair and receding temples.
community Dec 2024 vs now (min + fin/dut)
The user experienced hair thickening and reduced shedding using minoxidil, finasteride, and dutasteride, with a switch from finasteride to dutasteride due to ineffectiveness. They also use a saw palmetto shampoo and take vitamin D3 supplements, while considering potential underlying causes like vitamin deficiencies and hard water buildup.
community Being non responsive on dut and min
The user is experiencing hair loss despite using dutasteride, minoxidil, and ketoconazole shampoo, and is concerned about continued shedding. Suggestions include checking for nutrient deficiencies, consulting a dermatologist, and considering other potential causes like seborrheic dermatitis or telogen effluvium.
community If Dr. Tsuji’s stem cell multiplication procedure works, will it be effective for those with DUPA?
Dr. Tsuji's stem cell hair multiplication procedure may offer a future solution for hair loss, but it is initially expected to be very expensive, with prices potentially decreasing over time. In the meantime, users discuss using treatments like finasteride, despite side effects, to manage hair loss.
community So basically we will know the efficacy of HMI-115 in 3 months after the phase II study concludes in China?
Hair loss discussion mentions HMI-115 efficacy in 3 months after Phase II study. Users discuss treatment effectiveness and mention massive regrowth in previously bald areas.
community Amplifica and AMP-303 clinical phase 1
Amplifica is testing a compound called AMP-303 for hair loss, but it's not Scube3 or osteopontin. The timing for the results from the clinical trial is unknown.
community We always hear that DUT only lowers scalp DHT by 50% (fin at 40%) but a study within the hair follicle itself shows that DUT nukes DHT to near undetectable levels... so which is it??
Dutasteride significantly reduces DHT levels in hair follicles, potentially more effectively than previously thought. The discussion highlights differences in DHT measurements and the impact on hair loss treatment.
community If PP405 works it will be fkn impossible to buy it.
PP405 is a potential hair loss treatment that may activate dormant hair follicles, but there are concerns about its effectiveness, cost, and side effects. Users discuss treatments like minoxidil, finasteride, and RU58841, expressing skepticism about PP405's long-term success and accessibility.
community AA and Hirsutism but T levels are normal
27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.
community 2-deoxy-D-ribose (2dDR), a sugar molecule, was found to be 80%-90% as effective as minoxidil in promoting hair growth and neovascularization in androgenic alopecia models, showing promise for alopecia treatment.
2-deoxy-D-ribose, a sugar molecule, is found to be 80%-90% as effective as Minoxidil in promoting hair growth, showing potential for alopecia treatment. Concerns include high cost, lack of human studies, and possible side effects like diarrhea and nausea.
community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders
Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.
community Concerned About Asymmetrical Frontal Hair Loss and Recent Finasteride Use, Seeking Experiences
The user is experiencing asymmetrical hair loss at the frontal hairline and is concerned about potential conditions like frontal fibrosing alopecia. They have started using finasteride and pumpkin seed oil to address the issue.
community PYRILUTAMIDE VS RU58841 users which is superior
Hair loss treatments, with users discussing their experiences with both RU58841 and Pyrilutamide, noting that the latter has only recently become available but may yield better results in the long term.
community Reduced excessive hair shedding
community blood DHT levels shot up after doubling dutasteride dosage
A user increased their dutasteride dosage from 0.5mg to 1mg daily, resulting in a rise in DHT levels from 148 pg/mL to 281 pg/mL, and is considering switching back to finasteride due to continued hair loss. Replies suggest retesting and emphasize the importance of bloodwork before starting treatments.
community Increased efficacy of fin/dut: with or without meal?
Taking dutasteride with a meal containing fat may improve absorption, but consistency in routine is more important than timing. Minor variations in absorption won't significantly affect efficacy due to dutasteride's long half-life.
community Anyone here have a lot of knowledge on hair follicle stem cells and progenitor cells for PP405?
Hair follicle stem cells remain in bald individuals, but progenitor cells do not, raising questions about hair regrowth claims by Pelage. PP405 is discussed as a potential treatment, with skepticism about its effectiveness compared to existing treatments like Minoxidil and Finasteride.
community 2 years of dut, 1 year of loss 24m
The user experienced hair regrowth with dutasteride but later lost progress despite using minoxidil foam and dermastamping. Suggestions included reducing dermastamping frequency, conducting blood tests, and considering oral minoxidil or different brands of dutasteride.
community Creatine's effect on Hair Loss and DHT
A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.
community 14 months into fin + min and my hair is way worse than before
The user experienced worsening hair loss despite using finasteride, minoxidil, and microneedling. Suggestions included reducing microneedling frequency, switching to oral minoxidil, adding tretinoin, and considering dutasteride.
community (Serious) News and discussion on potential treatments
Current hair loss treatments include finasteride, dutasteride, minoxidil, and derma rolling. New treatments like TDM-105795, GT20029, and others show promise but require more testing and time before approval.