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GlossaryPlica Neuropathica

hair becomes severely matted and tangled into a dense mass

Plica Neuropathica, also known as Polish Plait or Plica Polonica, is a rare condition where hair becomes severely matted and entangled, forming a hard, dense mass. This can result from neglect, poor hair care, or certain scalp conditions, and may sometimes be associated with psychological or neurological disorders. Treatment typically involves cutting the matted hair and addressing any underlying issues.

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community Can I add rosemary oil to my hair lotion?

in Product 2 upvotes 3 years ago

A user asked if adding rosemary oil to a herbal hair lotion would be beneficial for preventing future hair loss and maintaining hair health. The lotion already contains various ingredients like seed extracts, proteins, and vitamins.

community My current regimen for MPB

5 upvotes 8 years ago

The user is treating hair loss with dermarolling, a laser helmet, scalp massages, and Nizoral. They stopped using minoxidil and finasteride and are considering pumpkin seed oil and sulforaphane.

community Update after 14 months posted last September

in Minoxidil 870 upvotes 5 months ago

The user successfully regrew hair using 1.2mg finasteride and 3mg minoxidil daily, without a hair transplant. They experienced significant improvement over 14 months, leading to positive changes in their appearance and confidence.

community New 2025 study: high dose oral minoxidil (up to 10mg)

in Research/Science 80 upvotes 7 months ago

High-dose oral minoxidil (>5 mg/day) can increase hair density in some men with androgenetic alopecia, but side effects like extra body hair and heart issues are common. Gradual dose increase is advised, but adverse effects may lead to discontinuation or dose adjustments.

community P5P supplementation for fin sides.

in Treatment 7 upvotes 4 years ago

P5P supplementation helped reverse finasteride side effects, particularly by lowering prolactin levels and restoring sensitivity. The user experienced significant improvement within a day and full recovery in a few days.

community 15 years old bad hair loss! I need tips

in Update 8 upvotes 7 years ago

Hair loss since age 13 due to scalp disease with dandruff, flaking, and itching. Seeking advice on using Minoxidil for regrowth and other tips.

community This is what some balding dudes are like

in Satire 1047 upvotes 1 year ago

Some people avoid finasteride due to side effects but engage in unhealthy habits. Minoxidil and finasteride are common hair loss treatments, with varied side effect experiences.

community Is hair thinning or loss associated with pain?

in Research/Science 6 upvotes 3 years ago

Hair thinning/loss associated with burning scalp pain. Finasteride helped relieve "DHT itch" for one person.

community if Post Finasteride Syndrome is real. Why is it only the negative effects and not positive have log term effect?

in Finasteride/Dutasteride 63 upvotes 3 weeks ago

Finasteride is used for hair loss, with mixed reports of no side effects and claims of long-term negative effects known as Post Finasteride Syndrome (PFS). The conversation debates the existence and causes of PFS, with differing opinions on whether it is psychological or real.

community M22, The dermatologist has prescribed me other products instead of minoxidil and finasteride.

in Product 166 upvotes 5 months ago

A dermatologist prescribed alternatives to Minoxidil and Finasteride for hair loss. Users recommend sticking with Minoxidil, Finasteride, or Ketoconazole shampoo and suggest seeking a second opinion.

community I'm quitting finasteride after almost 3 years of daily use

in Finasteride/Dutasteride 166 upvotes 7 months ago

A 23-year-old stopped using finasteride due to sexual side effects after three years. The discussion covers experiences with finasteride, dutasteride, and other treatments, noting varied side effects and effectiveness.

community Scientists May Have Accidentally Found a Way to Reverse Hair Loss Without Drugs

in Research/Science 883 upvotes 9 months ago

2-deoxy-D-ribose is being explored as a hair loss treatment but is not proven effective in humans and may be costly and inconvenient. Minoxidil remains the most effective treatment.

community Minoxidil Finasteride heart problems

in Update 97 upvotes 2 years ago

A user experienced heart problems after taking 1mg finasteride and 2.5mg oral minoxidil and is considering quitting minoxidil. Others discussed their experiences with heart issues and minoxidil, with some suggesting topical minoxidil as a safer alternative.

community Do you recommend oral minoxidil after your full experience?

in Minoxidil 9 upvotes 2 years ago

LemonyBonobo started oral minoxidil a week ago, experiencing significant shedding, and is concerned about potentially worsening their hair condition. They also use dutasteride, topical minoxidil, and dermarolling. Elyktronix, who has been on oral minoxidil for 15 months, recommends it, noting that shedding can be a positive response and that results take time.

community Killing the Norwood Reaper, a Journey

in Progress Pictures 370 upvotes 2 years ago

The user is treating hair loss with a regimen including Dutasteride, oral and topical Minoxidil, microneedling, and various supplements for overall health. They are considering adding tretinoin, stemoxydine/RU, DIM, Boron, and Fadogia Agretis to their routine.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 111 upvotes 2 years ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community Just had this wild thought come into my head.

in Satire 403 upvotes 2 years ago

The conversation is about the debate over the existence of Post-Finasteride Syndrome (PFS) and its symptoms, with some users skeptical about PFS and others discussing side effects like erectile dysfunction and gynecomastia from hair loss treatments like finasteride. Specific treatments mentioned include finasteride, viagra, and a joke about using a popsicle stick for erectile support.

community Medications that cause extra hair growth

in Research/Science 123 upvotes 2 years ago

The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

community DIY treatment... Shedding completely stopped after 1.5 yrs

in Treatment 252 upvotes 4 years ago

Vitamin C mixed with shampoo stopped shedding and promoted hair regrowth after 1.5 years. Both the person and their wife experienced significant hair loss reduction with this method.

community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.

in Research/Science 13 upvotes 1 year ago

A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 50 upvotes 1 year ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community scarring alopecia awareness in this community

in Chat 33 upvotes 3 years ago

Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

community Anger and frustration as I finally learn my diagnosis.

in Female 6 upvotes 2 years ago

A young female diagnosed with Lichen planopilaris (LPP) experienced years of misdiagnosis and ineffective treatments, including a hair transplant and other procedures. She is considering litigation due to the misdiagnosis and has learned that LPP is chronic, hair loss can be stopped with ongoing medication, but lost hair cannot regrow.

community Scalp tension and thickness of the galea aponeurotica, inflammation and potential treatment pathways

in Research/Science 4 years ago

Scalp tension potentially affecting hair loss, and potential treatments for male pattern baldness such as Minoxidil, Finasteride and RU58841. Evidence from a study was discussed which suggests that the cause of MPB lies within the follicle itself and is not dependent on its surrounding environment.

community DUPA - Impossible to cure, so giving up

in Update 3 upvotes 7 months ago

The user diagnosed with DUPA tried treatments like dutasteride, finasteride, RU58841, and minoxidil without success and is considering a hair system. They hope for a future cure, possibly with PP405, and others suggest options like scalp biopsy and SMP.

community Treating my DUPA via controlling inflammation

in Treatment 5 upvotes 2 years ago

The user has DUPA and suspects autoimmune activity as a cause. They have tried various treatments including finasteride, minoxidil, dutasteride, pyrilutamide, estrogel, hydrocortisone, and clobetasol, and are now seeking a long-term immunosuppressant.

community Will Pelage include Norwood 7 hair loss in PP405 phase 3 trials to see its true regenerative potential?

in Chat 5 upvotes 4 months ago

Norwood 7 hair loss is often excluded from trials to ensure treatments appear more effective and to reduce costs. Some believe treatments effective for Norwood 5 could work on Norwood 7, but companies prioritize market readiness.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Why I believe PFS is not a "real" condition (and what I believe it is instead)

in Finasteride/Dutasteride 15 upvotes 3 years ago

The post argues that Post-Finasteride Syndrome (PFS) is likely not real and suggests symptoms may be due to mental health issues or the nocebo effect. The conversation includes personal experiences with finasteride, highlighting both positive and negative effects, and emphasizes consulting doctors and using reliable sources for medication.

community Pili migrans? Lichen something? Seb derm?

in Female 19 upvotes 1 year ago

The conversation is about a female experiencing hair loss and seeking advice on why it's difficult to regrow hair. Specific treatments like Minoxidil, finasteride, or RU58841 are not mentioned.