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GlossaryPrurigo Nodularis

chronic skin condition with itchy, hard nodules

Prurigo Nodularis (PN) is a chronic skin condition characterized by the presence of hard, itchy nodules that often appear on the arms, legs, and other parts of the body. These nodules are typically a result of persistent scratching or rubbing, which can lead to further skin damage and a cycle of itching and scratching.

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research The use of biodegradable microneedle patches to increase penetration of topical steroid for prurigo nodularis.

5 citations , January 2018 in “PubMed”

Biodegradable microneedle patches help topical steroids work better for prurigo nodularis.

research Dupilumab for a 5‐year‐old child with prurigo nodularis

2 citations , October 2023 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft”

Dupilumab significantly improved a 5-year-old girl's prurigo nodularis without side effects.

research Ivarmacitinib in atopic dermatitis presenting with prurigo nodularis-like lesions and alopecia areata: a case report

July 2026 in “Frontiers in Immunology”

Ivarmacitinib may effectively treat complex atopic dermatitis and related hair loss.

research Dupilumab for prurigo nodularis: real-world outcomes up to 104 weeks from the Dupilumab Italian Prurigo Nodularis (DUPItaPN) study

April 2026 in “Clinical and Experimental Dermatology”

Dupilumab effectively reduces symptoms of prurigo nodularis and is safe for long-term use.

research The patient journey in prurigo nodularis: what lies ahead

April 2026 in “Expert Opinion on Biological Therapy”

Prurigo nodularis is hard to diagnose and treat, but new biologics offer hope for better management.

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