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A 17-year-old is experiencing rapid hair loss from NW1.5 to NW3 in six months and feels dermatologists are unhelpful. They are using Minoxidil (Rogaine) and seeking advice on application.

Pyrilutamide, a potential hair loss treatment that is currently in development and may be available soon; an androgen receptor degrader which is also being developed as a potential treatment for hair loss; and the comparison between Pyrilutamide, finasteride, minoxidil, and RU58841.

A user discusses their extensive hair loss treatment regimen, which includes dutasteride, oral and topical minoxidil, RU58841, various supplements, and lifestyle changes. The conversation includes opinions on the effectiveness and necessity of such a comprehensive approach, with some users suggesting alternatives like microneedling and questioning the high dosage of dutasteride.

A 44-year-old man experienced significant hair regrowth after switching from topical to 1.25mg oral minoxidil and 0.5mg daily finasteride, with no side effects. He noticed hair thickening after two months and credits the oral form's effectiveness.

Pyrilutamide is officially available for purchase, and users suggest Fluridil as an alternative topical anti-androgen. Some users report positive results with pyrilutamide from Koshine.

The conversation discusses the difference between the commercially available Pyrilutamide and the version in clinical trials. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.

EdgeLord19941's progress with hair loss medication, which includes 0.5mg dutasteride daily, 5mg oral minoxidil daily and microneedling with an electronic pen once every 7-14 days at 1.5mm. There have been positive results reported within 3 months of following this regimen with no major side effects.

Microneedling can be effective for hair regrowth, especially when used with oils like castor, emu, and rosemary, but should be done with caution regarding needle size and frequency. Some users avoid minoxidil due to its side effects and cost, opting for alternatives like rosemary oil.

A dermatologist recommended a new supplement containing annurca apple, which reportedly doubles hair density and increases keratin after 60 days, to be used with finasteride. Some users are skeptical, considering it potentially ineffective or a marketing ploy, while others are open to trying it if it proves effective and affordable.

The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.

The user is considering changing their hair loss treatment from topical minoxidil and oral finasteride to oral minoxidil and oral dutasteride, with suggestions to add microneedling and possibly red light therapy. They are also exploring the addition of a caffeine and adenosine mix to their regimen.

RU58841 was used by some for hair loss, but concerns about side effects like gynecomastia and safety were raised. Alternatives like finasteride, minoxidil, pyrilutamide, and alfatradiol were discussed, with some users reporting better experiences with these treatments.

Blocking the Mitochondrial pyruvate carrier and using aldose reductase inhibitors like Indian gooseberry and berberine may help with hair growth. Magnesium can also be added to increase NADPH.

The user experienced significant hair regrowth after 7 months using topical minoxidil once a day and 0.5mg dutasteride every other day, with noticeable results in the last two to three months. They reported no side effects and did not use dermarolling.

A 35-year-old who has been using topical and oral Minoxidil and Finasteride with dermarolling and Nizoral for four months, experiencing improved hair health but not yet full coverage on the crown. Others have responded encouragingly to this progress.

A progress update of hair growth while taking 1 mg finasteride daily, minoxidil daily before bed, nizoral a few times a week and derma rolling weekly.

Microneedling with finasteride, minoxidil, DMSO, and black seed oil shows mixed hair regrowth results. There are concerns about DMSO's safety and effectiveness.

A user's regimen to help with their diffuse thinning, which includes taking Pyrilutamide BID, 1mg finasteride daily, 2.5mg oral minoxidil daily, topical minoxidil since August 2021, LLLT every two days, topical fin, progesterone, melatonin, minoxidil (started one week ago), pumpkin seed oil and not dermarolling; other commenters suggested Nizoral for dandruff control and caution when using pre-mixed products with Pyrilutamide.

The user is seeking advice on hair loss treatment after three months on finasteride, having stopped minoxidil due to a rash, and is now using nanoxidil. Suggestions include switching to oral minoxidil, adding dutasteride, and incorporating microneedling for better results.

A user's 14-month journey with finasteride, microneedling, and Nizoral to treat hair loss. They experienced some side effects such as ball ache, needing to pee constantly, and less semen, but the results were generally positive.

The conversation discusses transitioning from topical to oral minoxidil for hair loss treatment and explores the potential use of Aminexil, despite concerns about its effectiveness compared to minoxidil. It highlights the risks and side effects of oral minoxidil, such as potential heart and liver damage, and emphasizes the importance of monitoring blood pressure.

Users discuss using pyrilutamide for hair loss, seeking alternatives to 5AR inhibitors. They mention using minoxidil, ketoconazole shampoo, and RU58841.

User discusses using Finasteride, Minoxidil, and Microneedling for hair loss. They gradually replaced Finasteride with Dutasteride and stopped using Nizoral shampoo due to shedding.

The user shared progress photos showing hair regrowth after using Minoxidil, Finasteride, and Nizoral since mid-2023, and plans to replace derma rolling with Tretinoin. They discussed their routine, the initial shedding phase, and their experience with side effects, while others commented on the visible improvement.

A 29-year-old male is using topical minoxidil and microneedling for hair regrowth and is considering adding finasteride. Users suggest adding finasteride for better results.

Hair loss treatments, with users discussing their experiences with both RU58841 and Pyrilutamide, noting that the latter has only recently become available but may yield better results in the long term.

The user started 2.5mg oral minoxidil 4.5 months ago and 1mg finasteride 1 month ago for hair loss. They are concerned about thinning hair and receding temples, but others suggest their hair looks good and recommend considering a hair transplant.

The conversation discusses a user's positive experience with a hair loss treatment routine involving dutasteride, oral minoxidil, and Nourkrin Man, with no side effects reported. Other users share their experiences with similar treatments, discussing side effects like heart palpitations and depression, and offer advice on obtaining prescriptions affordably.

Applying minoxidil immediately after microneedling at 0.5mm can cause stinging and potential systemic absorption, so some users prefer to wait 12-24 hours. Others report no issues with immediate application, but caution is advised to avoid irritation and side effects.