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      community What’s your nuclear protocol???

      in Chat  20 upvotes 2 years ago
      People discussed their intense hair loss treatments, including the use of dutasteride, RU58841, minoxidil, tretinoin, essential oils, microneedling, and various topical sprays. Some users reported success with these methods in preventing hair loss and stimulating hair growth.

      community Once daily topical Min, weekly 1.5 mm dermarolling

      in Progress Pictures  35 upvotes 2 years ago
      The user has been using 5% minoxidil once daily and microneedling with a 1.5 mm dermaroller weekly for three months, considering increasing minoxidil usage but avoiding finasteride due to libido concerns. Another person suggests considering other treatments like RU58841, alfatradiol, topical finasteride, clascoterone, or saw palmetto since not using a DHT blocker could be less effective.

      community Update on dut and min (thought I was a non responder)

      in Update  11 upvotes 1 month ago
      The user is using dutasteride and minoxidil for hair loss and noticed new hair growth after initially thinking there was no progress. Encouragement was given to continue the treatment as it takes time to see full results.

      community Doing nuclear stack. Is there anything else I could do?

      in Treatment  6 upvotes 1 year ago
      The conversation discusses a comprehensive hair regrowth regimen including Dutasteride, Finasteride, microneedling, RU58841, oral and topical Minoxidil, Tretinoin, and Vitamin D3. Suggestions include dropping Finasteride, increasing Dutasteride, and considering additional treatments like caffeine, melatonin, and laser therapy, while emphasizing the effectiveness of Dutasteride and Minoxidil.

      community DUPA - 20 YO - Non responder to everything

      in Finasteride/Dutasteride  13 upvotes 1 year ago
      A 20-year-old user experienced worsening hair loss despite using various treatments including topical and oral minoxidil, finasteride, and dutasteride. Other users suggested additional treatments like JAK inhibitors, RU58841, and lifestyle changes, but the user remains skeptical and frustrated.

      community Minoxidil, RU58841, CB-03-01, WAY-316606, and derma stamping.

      in Minoxidil  5 upvotes 6 years ago
      The user is using Minoxidil, RU58841, CB-03-01, WAY-316606, Ketoconazole, MK-677, and derma stamping to treat hair loss and has noticed new hair growth, especially around the temples and hairline. They apply different treatments at various times of the day and have seen improvements in skin condition and body hair texture.

      community Anyone ever use amazons RU58841?

      in Product  21 upvotes 2 years ago
      The conversation warns against buying RU58841 from Amazon due to concerns about product authenticity and recommends purchasing from trusted sources like Minoxidilmax and Anageninc.

      community About GT20029's Efficacy and Strength

      in Chat  7 upvotes 3 years ago
      The conversation is about the effectiveness and production of GT20029, a drug being developed as a topical androgen receptor degrader for hair loss, and whether it can fully degrade androgen receptors or only partially. It also discusses the drug's potential unique working mechanism and synthesis by a company called Anagen.

      community Update: going nuclear! (Switch to dut)

      in Update  13 upvotes 2 months ago
      The user had a hair transplant in March 2025 and has been using finasteride since 2023, which halted hair loss but didn't fully restore density. They plan to use dutasteride twice weekly, finasteride five times a week, and saw palmetto to improve hair thickness.

      community M29 Dut/Min/Microneedle/Tretinoin

      in Is this regrowth?  22 upvotes 1 year ago
      A user has been using finasteride since 2018, switched to dutasteride, and added minoxidil, microneedling, and a tretinoin/spiro compound. They are pleased with the results and hopeful for more improvement.

      community (Serious) News and discussion on potential treatments

      in Treatment  28 upvotes 1 year ago
      Current hair loss treatments include finasteride, dutasteride, minoxidil, and derma rolling. New treatments like TDM-105795, GT20029, and others show promise but require more testing and time before approval.

      community Pelage PP405 Phase 2a completed.

      in Research/Science  61 upvotes 4 months ago
      Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss, with excitement around a new drug, PP405, and a reformulated oral minoxidil in trials. Concerns about cost, side effects, and long-term use are also mentioned.

      community Nanoxidil: a good substitute or a scam?

      in Treatment 1 year ago
      Nanoxidil is considered by some as a substitute for Minoxidil, but users report it as ineffective and expensive. Finasteride is recommended as a more effective treatment, often used with Minoxidil, microneedling, and ketoconazole.

      community 20% discount code at Anageninc

      in Chat  2 upvotes 1 year ago
      A discount code for 20% off at Anageninc is shared, valid for purchasing RU58841 or Pyri from May 10-11, 2025. The conversation focuses on hair loss treatments using RU58841.

      community any Ru58841 user ? + What do I need to expect?

      in Product  10 upvotes 1 year ago
      The user is considering adding RU58841 to their current hair loss treatment of finasteride and minoxidil, but is concerned about potential side effects like hairline recession and shedding. Some users report positive results with RU58841, while others experience side effects such as chest pain and dizziness.

      community I think microneedling before topical application of finasteride (or dut) is a path we should investigate (for those of us who don't care about systemic absorption). Here's why...

      in Microneedling  20 upvotes 9 months ago
      Microneedling before applying topical finasteride or dutasteride may enhance their effectiveness by increasing local absorption in the scalp, despite concerns about systemic absorption. Users discuss combining this method with oral treatments and minoxidil, noting potential benefits and side effects.

      community 5 Months Redensyl + Dermarolling

      in Progress Pictures  16 upvotes 2 years ago
      The user started treating their slightly thinning, receded hairline with a serum containing Redensyl and other ingredients, and dermarolling weekly. They recently began taking finasteride and plan to stop Redensyl in the future to test if hair loss resumes.

      community PROGRESS ON NEW ROUTINE - DUT/Minox/Microneedling

      in Progress Pictures  6 upvotes 7 months ago
      The conversation is about a user's hair loss treatment progress using a routine of Avodart (Dutasteride), oral and topical Minoxidil, Ketoconazole shampoo, and microneedling. The user reports no side effects and shows improvement after resuming consistent treatment.

      community Topical min and dermarolling with seborrheic dermatitis

      in Minoxidil  4 upvotes 2 months ago
      The user is managing hair loss with oral finasteride, recently switching to dutasteride, and topical minoxidil, but faces challenges due to seborrheic dermatitis. They seek advice on effective regrowth methods that don't worsen their condition, with suggestions including various shampoos like Vichy Dercos and ketoconazole.

      community I'm becoming non-responder to minoxidil. What's going on?

      in Minoxidil  7 upvotes 10 months ago
      The user experienced reduced effectiveness of minoxidil after consistent use, despite using dutasteride to maintain hair. They are considering alternatives like microneedling and exploring options like hair transplants due to dissatisfaction with current hair density.

      community Is this the 2026 Hairloss Nuclear Stack?

      in Finasteride/Dutasteride  29 upvotes 3 months ago
      A user discusses their extensive hair loss treatment regimen, which includes dutasteride, oral and topical minoxidil, RU58841, various supplements, and lifestyle changes. The conversation includes opinions on the effectiveness and necessity of such a comprehensive approach, with some users suggesting alternatives like microneedling and questioning the high dosage of dutasteride.