Topical dutasteride is considered for hair loss, but concerns about systemic absorption and sideeffects like reduced libido are common. Users have mixed results, with some preferring oral finasteride or dutasteride despite sideeffects, while others find topical treatments beneficial but challenging.
The user experienced concerning sideeffects like throat irritation, shortness of breath, chest pain, and testicle pain after using RU58841 for hair loss, despite also using finasteride and minoxidil. Other users shared mixed experiences, with one advising to stop using RU58841 due to similar sideeffects, while another reported significant hair loss reduction without sideeffects.
A peptide-based delivery system for finasteride shows promise in reducing systemic sideeffects while maintaining hair growth effectiveness. Combining this with other treatments like minoxidil and RU58841 could enhance results with lower systemic absorption.
The user is using topical dutasteride, finasteride, minoxidil, and tretinoin but seeing no results or sideeffects. They also microneedle every two weeks but experience little bleeding, questioning if a thick scalp is preventing treatment effectiveness.
Topical finasteride is less popular due to inconvenience, cost, and availability, while oral finasteride is favored for ease and safety. Some users experience sideeffects with topical use, but find it effective with minoxidil, though opinions on its efficacy vary.
A 22-year-old male is switching from topical to oral minoxidil due to limited results with topical use, while continuing oral finasteride and considering sideeffects. Users discuss experiences with oral minoxidil, noting potential sideeffects like swelling and headaches, but also its effectiveness compared to topical treatments.
The conversation humorously discusses starting oral microneedling for hair loss, with mentions of sideeffects like internal bleeding and abdominal pain. It also references using treatments like minoxidil and finasteride, with exaggerated and satirical comments on their effects.
A user experiencing sideeffects from a 5% minoxidil and 0.1% finasteride topical solution for hair loss reduced their dosage due to numbness and pain in the lower body and is seeking advice on dosage and alternatives like redensyl. They are concerned about the sideeffects of both medications and are considering adjusting the dose or switching treatments.
Concerns about using 0.3% topical finasteride due to potential sideeffects like decreased libido and gynecomastia. Suggestions include using less than 1ml or considering 1mg oral finasteride.
Concerns about the long-term safety of VDPHL01, an extended-release minoxidil, due to potential risks similar to Cantu syndrome, were raised, highlighting the lack of monitoring for chronic connective tissue changes. The conversation suggests that while the treatment may improve hair growth, it could lead to issues not detected in short-term trials.
Pyrilutamide shows minimal systemic absorption with low plasma levels and no accumulation, suggesting it's unlikely to cause systemic sideeffects. However, full results are not yet published in scientific journals.
The sideeffects of taking finasteride as a treatment for hair loss, with particular focus on its sexual and psychiatric sideeffects; research has indicated that there are high and low outliers in terms of prevalence of sexual sideeffects, but it is usually between 3-5%, while evidence of lasting sexual sideeffects comes from lower quality sources.
Switching from topical to oral minoxidil may lead to better results for some users, with oral minoxidil generally being more effective due to higher absorption. However, it can also cause sideeffects like hypertrichosis and blood pressure issues, and individual responses may vary.
The conversation discusses the potential of using topical estrogen treatments for hair loss without systemic absorption, highlighting challenges and possible solutions like using estriol. It also mentions other treatments like topical finasteride, microneedling, and scalp massage, while noting the limitations and sideeffects of current options.
A user who has been using Pyrilutamide for 19 days, experiencing some hair thickening in the right temple and crown area but also having ball ache after microneedling; other users offer advice, caution and skepticism as to whether results can be seen in such a short time.
Topical dutasteride, especially at higher concentrations, can be effective for hair loss when combined with microneedling to enhance absorption. Users discuss the sideeffects of finasteride and dutasteride, with some preferring topical treatments to avoid systemic sideeffects.
Oral minoxidil is considered more convenient and effective than topical or sublingual forms, with users reporting positive results and minimal sideeffects. Some users experience sideeffects with oral minoxidil and opt for sublingual or topical methods instead.
A user experienced severe sideeffects, including heart-related symptoms, after increasing their oral minoxidil dosage to 5 mg, leading them to stop the medication and seek medical advice. Many users advised against high doses of oral minoxidil, suggesting anxiety as a possible cause, and recommended consulting a doctor or switching to topical treatments.
Low-dose topical finasteride may reduce scalp DHT with fewer sideeffects than oral finasteride, though it can still lower blood serum DHT. Users report varying experiences, with some finding topical use effective and side-effect-free, while others note significant DHT suppression.
RU58841 stopped scalp itching for the user, providing relief from persistent itchiness associated with hair loss. Some users reported sideeffects like chest pain, while others found relief with different treatments like mometasone.
Microneedling the scalp can cause sneezing, runny nose, and watery eyes due to nerve stimulation, histamine release, reflex actions, or sinus relief. Several users experience similar symptoms.
User discusses topical liposomal finasteride for hair loss, hoping to avoid breast growth side effect. Conversation includes using minoxidil, fluridil, and dermarolling, and mentions minimal systemic absorption of liposomal finasteride.
The conversation is about adjusting the dosage of topical Finasteride to avoid sideeffects like chest pain and breast swelling. The user is considering reducing the concentration to 0.1% or trying microdosing with 0.01-0.025% for lower systemic effects.
The conversation discusses using a lipodermal solution for hair loss, with concerns about sideeffects from multiple active ingredients. Users mention experiences with minoxidil, finasteride, and dutasteride, noting sideeffects like brain fog and sexual issues.
The conversation discusses the use of low-dose oral minoxidil for hair loss and its potential effects on skin aging. Users shared experiences, with some noting sideeffects like puffy eyelids and dark circles, but no conclusive evidence of significant collagen depletion or increased wrinkles.
Clascoterone (CB) shows an excellent safety profile with no serious sideeffects, but its effectiveness may decline after six months, making it more suitable as an adjunct treatment with finasteride and minoxidil rather than a standalone solution. Some argue it could be better than finasteride due to its protection against testosterone, but its long-term efficacy remains debated.