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GlossaryOtotoxicity

property of being toxic to the ear, causing hearing loss

Ototoxicity refers to the property of being toxic to the ear, specifically the cochlea or auditory nerve and sometimes the vestibular system, which can result in hearing loss or balance disorders. This condition is often caused by certain medications or chemicals, such as aminoglycoside antibiotics or chemotherapy agents, which can damage the inner ear structures.

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community The Effects of the Potassium Channel Opener Minoxidil on Renal Electrolytes Transport in the Loop of Henle

in Minoxidil 7 upvotes 4 years ago

This post and conversation are about the effects of Minoxidil on renal electrolytes transport in the Loop of Henle. The replies show a lack of interest and a brief summary stating that rectal Minoxidil electrolytes are bad.

community Worried after using minoxidil once in a home with cats

in Female 5 upvotes 3 months ago

A user applied minoxidil for hair loss and worried about its toxicity to cats after their cat drank from a water fountain they touched. After consulting a vet and pet poison control, they were reassured that the exposure was not enough to harm the cat, and others advised using gloves and being cautious in the future.

community Min. liquid caused headaches and eye irritation. Better results with foam?

in Minoxidil 4 upvotes 5 years ago

Liquid Minoxidil caused headaches and eye irritation, possibly due to propylene glycol. Switching to foam may reduce side effects.

community Be careful with minoxidil, even if it's just foam.

in Minoxidil 12 upvotes 1 year ago

Minoxidil caused side effects like chest pain and tinnitus for the user, leading them to stop using it and consider switching to finasteride with microneedling. Other users shared similar experiences with minoxidil, while some reported no issues, highlighting varied individual reactions.

community Hair transplant histamine issues (could be antibiotics taken during transplant!?)

in Transplants 1 upvotes 2 years ago

User experienced severe allergic reactions and liver issues after a hair transplant, likely due to antibiotics and medications. Despite trying Minoxidil, the user faced further complications and is now seeking medical advice for potential future transplants.

community Has anyone experienced burning scalp after chemical damage (perm)?

in Chat 6 upvotes 6 months ago

A user experienced burning, itching, and soreness on their scalp after a perm in 2021, despite using oral finasteride, oral minoxidil, and ketoconazole shampoo. They are seeking advice on whether to pursue further medical tests or consult a neurologist for nerve pain.

community Why is oral minoxidil more dangerous than spironolactone?

in Minoxidil 6 upvotes 5 years ago

The conversation is about the perceived risks of oral minoxidil compared to spironolactone for treating hair loss, with the original poster currently taking spironolactone due to concerns about oral minoxidil's safety.

community Minoxidil and concern about cats

in Minoxidil 5 upvotes 9 months ago

Minoxidil is highly toxic to cats, and even small amounts can be fatal. The user decided against using topical minoxidil due to the risk to their cats and considered oral minoxidil and ketoconazole shampoo as alternatives.

community Minoxidil is highly toxic to pets — help push for proper labeling [Petition]

in Minoxidil 251 upvotes 8 months ago

Minoxidil is highly toxic to pets, particularly cats and dogs, and there is a call for proper labeling to warn pet owners. Despite some skepticism about the effectiveness of petitions, many agree that awareness and caution are necessary to prevent accidental poisoning.

community experience report: oral minoxidil + sodium reducing diuretic (furosemide)

in Minoxidil 3 upvotes 1 year ago

The user reports taking high dosage oral minoxidil (10mg/day) for hair growth, which causes facial bloating. They tried using the diuretic furosemide to reduce bloating, but it was ineffective.

community RU58841 toxic to cats like minoxidil?

in Product 1 upvotes 1 year ago

RU58841's potential toxicity to cats is uncertain, similar to minoxidil. Caution is advised to prevent accidental exposure to pets.

community Important detail for Oral Minoxidil users

in Minoxidil 9 upvotes 1 week ago

Oral minoxidil users should monitor heart health with periodic echocardiograms and cardiologist visits due to potential side effects. While some experience serious side effects, they are rare, and the benefits for hair growth often outweigh the risks.

community The Biggest Concern That I Have For Oral Minoxidil: Cardiac Hypertrophy

in Minoxidil 27 upvotes 2 years ago

Oral minoxidil can cause serious heart issues like cardiac hypertrophy and arrhythmias, prompting some users to reduce dosage or switch to topical treatments. Despite significant hair regrowth, side effects such as shortness of breath and chest pains are common concerns.

community Minoxidil causes eye issues as per this article

in Minoxidil 3 months ago

Minoxidil is discussed as a hair loss treatment, with concerns about potential eye issues. Some users express skepticism about these claims, while others emphasize the long-standing use of Minoxidil.

community Sublingual topical minoxidil experience

in Minoxidil 16 upvotes 4 years ago

A user experienced severe side effects from using topical minoxidil sublingually, including muscle cramps, dizziness, and high potassium levels. They were advised to stop and seek medical help, emphasizing that topical minoxidil is not safe for ingestion due to its alcohol content.

community Potassium and oral min need each other??

in Minoxidil 4 upvotes 1 year ago

Oral minoxidil may require potassium for effectiveness, and diuretics taken for water retention might affect this process. The user plans to start taking potassium to address potential issues with minoxidil's effectiveness.

community Is stemoxydine (serioxyl advanced) toxic/lethal to cats?

in Chat 1 upvotes 1 year ago

The conversation is about concerns regarding the safety of using stemoxydine (Serioxyl Advanced) around cats, with the user also using minoxidil, oral minoxidil, dutasteride, and microneedling for hair loss. The user is seeking advice on whether stemoxydine is toxic or lethal to cats.

community Warning: Minoxidil usage around pets

in Minoxidil 454 upvotes 1 year ago

Minoxidil is highly toxic to pets, especially cats and dogs, even in small amounts. Many users have switched to oral minoxidil to prevent accidental exposure to their pets.

community Drinking minoxidil lands human in ICU with shock and heart failure

in Minoxidil 804 upvotes 1 year ago

A person mistakenly drank an entire bottle of topical minoxidil, leading to ICU admission with shock and heart failure. The incident highlights the dangers of ingesting topical treatments and the importance of proper usage and dosage.

community There's parabens in my Minoxidil, how bad is that?

in Minoxidil 2 upvotes 7 years ago

Parabens in Minoxidil are a concern for some users due to potential health risks. The conversation discusses the presence of methylparaben and propylparaben in a specific Minoxidil brand, Ylox.

community New study shows minoxidil tropical solution 5% can cause eyesight problems.

in Research/Science 183 upvotes 1 year ago

Minoxidil 5% topical solution may cause eyesight problems, with some users experiencing blurred vision. The discussion also mentions finasteride's potential side effects, including erectile dysfunction, with varied personal experiences.

community Prolactin's role in antitumor activity of the immune system - a safety concern for HMI-115?

in Research/Science 5 upvotes 2 years ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Prolactin's role in immune system's antitumor activity raises safety concerns for HMI-115.

community Minoxidil its giving me huge water retention

in Minoxidil 128 upvotes 11 months ago

Minoxidil caused water retention and gastrointestinal issues for the user, which improved after stopping the medication. The user is now using finasteride and topical minoxidil, experiencing excessive urination and concerns about systemic absorption.

community Had to quit minoxidil because of headaches

in Minoxidil 15 upvotes 1 year ago

The user stopped using minoxidil due to headaches, which returned upon resuming the treatment, leading to hair shedding concerns. Alternatives like finasteride and diluted minoxidil were suggested by others experiencing similar side effects.

community Minoxidil’s mechanism of action on blood pressure as a potassium channel opening molecule

in Research 83 upvotes 1 month ago

Minoxidil works by opening potassium channels, leading to reduced blood pressure and potential side effects like reflex tachycardia. It is used for hair growth and affects blood pressure at high doses.

community How Dangerous is Oral Min Really?

in Minoxidil 26 upvotes 1 year ago

Oral minoxidil is generally effective for hair loss but may cause side effects like heart palpitations and facial puffiness. Users highlight the importance of monitoring blood pressure due to potential cardiovascular risks.

community Can liver problems be associated with response to the oral minoxidil?

in Research 147 upvotes 3 months ago

Liver problems may reduce the effectiveness of oral minoxidil due to impaired SULT1A1 enzyme activity, which is crucial for converting minoxidil to its active form. This reduction in enzyme function can significantly decrease the drug's effectiveness in promoting hair growth.

community Tretinoin can make it worse!!!

in Chat 7 upvotes 2 years ago

Tretinoin may enhance minoxidil's effectiveness for those not responding to minoxidil alone, but it could reduce efficacy for some who are already responding to minoxidil. Tretinoin requires careful use, including skin moisturizing and sun protection due to increased sensitivity.

community Being Safe on Oral Minoxidil: tl;dr on the literature.

in Research/Science 49 upvotes 1 year ago

Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

community Serious Oral Minoxidil Side Effects

in Minoxidil 30 upvotes 4 years ago

A user experienced severe side effects, including heart-related symptoms, after increasing their oral minoxidil dosage to 5 mg, leading them to stop the medication and seek medical advice. Many users advised against high doses of oral minoxidil, suggesting anxiety as a possible cause, and recommended consulting a doctor or switching to topical treatments.