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community Where are GT20029 phase II results?

in Research/Science 3 upvotes 2 years ago

The conversation is about the anticipation of results for a hair loss treatment study, specifically for GT20029, with expectations for the results to be released in the first quarter of 2024. No specific treatments were discussed.

community Will PP405 be prohibitively expensive or will it be roughly the same as fin or min?

in Research/Science 6 upvotes 9 months ago

PP405 is expected to be more expensive than finasteride and minoxidil initially due to patent protection, but not as costly as life-saving medications like Ozempic. The price may decrease after the patent expires, but initially, it might be around $100 per month, making it potentially unaffordable for many.

community Do finasteride/dutasteride actually inhibit only 40/50% scalp DHT

in Finasteride/Dutasteride 11 upvotes 2 years ago

Finasteride works by reducing DHT, which helps stop hair miniaturization. The user is on finasteride and believes it works due to its effect on growth factors and DHT reduction.

community Making PG free solution at home

in Product 1 upvotes 2 years ago

A user wants to make a solution for RU58841 and finasteride powder using only glycerin and asks if ethanol is necessary. They are seeking advice on whether glycerin alone is sufficient.

community Can we get a reality check on PP405?

in Research/Science 81 upvotes 8 months ago

PP405 is a promising hair loss treatment that may outperform minoxidil and finasteride by reviving dormant follicles and promoting significant regrowth. Results from ongoing trials are awaited, with a potential market release between 2028-2030.

community I wish pp405 work and i have full head of hair in 2028-2030

in Chat 106 upvotes 8 months ago

People are hopeful about future hair loss treatments like PP405, GT20029, and VDPHL01, while some are currently using finasteride and minoxidil. There is skepticism about the effectiveness of new treatments, and some advise against hair transplants until more promising drugs are available.

community RU and cetosomal minoxidil topical

in Minoxidil 1 upvotes 4 months ago

Mixing RU58841 with cetosomal minoxidil is discussed due to scalp irritation from ethanol PG vehicles. A mixture of the two turned bright pink when left to dry.

community Treatment of Finasteride Induced Gynecomastia (Male breast tissue growth)

in Finasteride/Dutasteride 16 upvotes 5 years ago

Finasteride can cause gynecomastia, which may be reversible by stopping the drug and using selective estrogen receptor modulators (SERMs) like tamoxifen. Lifestyle changes such as weight loss and avoiding alcohol can also help, but surgery may be needed if the condition persists.

community Minoxidil’s mechanism of action on blood pressure as a potassium channel opening molecule

in Research 83 upvotes 4 months ago

Minoxidil works by opening potassium channels, leading to reduced blood pressure and potential side effects like reflex tachycardia. It is used for hair growth and affects blood pressure at high doses.

community The story of RU58841/PSK3841

in Research/Science 1 year ago

RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

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