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      community "Dutasteride Ruined My Hairline!"

      in Finasteride/Dutasteride  36 upvotes 2 years ago
      The user has been on dutasteride for six months and experienced significant hair shedding, especially at the hairline, and is seeking advice. Some suggest continuing the treatment and being patient, while others share mixed experiences with dutasteride and consider switching back to finasteride or adding other treatments like RU58841.

      community 8 months apart on the mother of all stacks

      in Progress Pictures  151 upvotes 2 years ago
      User Tricky9555 tried various hair loss treatments for 8 months with no visible results. Others suggested considering a hair transplant, checking thyroid levels, and being patient for up to 24 months for potential results.

      community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?

      in Treatment  30 upvotes 3 months ago
      A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.

      community JXL082 is not PP405 and Everychem followed the wrong lead

      in Research/Science  41 upvotes 8 months ago
      JXL082 is not the same as PP405, leading to a halt in sales and a plan to synthesize the real PP405. There is skepticism about the safety and effectiveness of JXL082 and PP405, with concerns about patent issues and the long-term impact on hair growth.

      community Does anyone know the chemical formula for pelage pp405?

      in Research/Science  14 upvotes 1 year ago
      The conversation discusses the lack of public information on the chemical structure of PP405, a hair loss treatment, and the challenges of synthesizing it without a patent. It also explores a patent related to hydrogen-based topical formulations for reducing oxidative stress and inflammation.

      community The story of RU58841/PSK3841

      in Research/Science 1 year ago
      RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

      community New Dutasteride Long Term Study (5 years) it works.

      in Finasteride/Dutasteride  106 upvotes 2 years ago
      The conversation discusses a five-year study on dutasteride, a medication for male hair loss. The study found that 89.9% of patients saw improvement or prevention of hair loss progression, with varying success rates based on different balding patterns. Side effects were mostly sexual and decreased over time. Dutasteride was concluded to be a long-term, safe, and effective treatment for male hair loss.

      community Ligand Chem cease trading Pyrilutamide

      in Product  14 upvotes 3 years ago
      Pyrilutamide, a possible hair loss treatment, ceasing to be traded due to patent laws; and the hope that this indicates it may be a legitimate treatment.

      community new way to activate stem cells to make hair grow

       44 upvotes 7 years ago
      Stem cell-related treatments and drugs like RCGD423 and WAY are being tested for hair growth. Clinics are conducting tests on patients who haven't had previous treatments.

      community I might have found hair transplant bug guys

      in Transplants  5 upvotes 9 years ago
      Using finasteride before a hair transplant can prevent further hair loss and make the transplant look more natural. Patients should continue using finasteride until hair cloning becomes available.

      community How much DHT causes hair loss ?

      in Finasteride/Dutasteride  2 upvotes 5 months ago
      The user is taking 2.5 mg dutasteride and 5% minoxidil but is not seeing hair regrowth, and is considering adding RU58841. They are experiencing fatigue and low MCV/MCH, possibly related to dutasteride, and are advised to be patient, consider microneedling, and check for iron deficiency.

      community Unable to regrow hair, even though I am on a strong stack

      in Finasteride/Dutasteride  22 upvotes 8 months ago
      The user is using a combination of 7% minoxidil, 0.2% finasteride, 0.5mg finasteride, RU58841, and daily microneedling but is not seeing hair regrowth after 5 months. Suggestions include being patient, reducing microneedling frequency, considering oral minoxidil, and possibly switching to dutasteride if no improvement after a year.

      community 2800 FUE Asmed Koray Erdogan Istanbul, complete failure

      in Transplants  287 upvotes 8 months ago
      A user had a failed hair transplant with 2800 FUE grafts at a clinic in Turkey, where finasteride was used, and the procedure was poorly executed by technicians rather than the main surgeon. The user later sought repair from a more experienced doctor, highlighting issues with large clinics that handle multiple patients daily.

      community 8 years of hair loss, turning 30 next month

      in Progress Pictures  151 upvotes 9 months ago
      The user has been dealing with hair loss for 10 years, worsened by psoriasis, and uses minoxidil and finasteride. They seek advice on managing psoriasis and hair loss, with suggestions to see a dermatologist, try different shampoos, and be patient.

      community 1 week with Finasteride; experiences so far

      in Finasteride/Dutasteride  39 upvotes 1 year ago
      A 30-year-old man has been using Minoxidil for years with limited success and recently started Finasteride, experiencing minor side effects but hoping for regrowth. Other users suggest not overthinking, considering a buzz cut, and being patient for results.

      community Review of my consultation with Dr Zarev

      in Treatment  58 upvotes 2 years ago
      The user had a detailed 3.5-hour consultation with Dr. Zarev for hair loss treatment, praising his meticulous approach and innovative techniques, and was prescribed topical finasteride and minoxidil. Other users agreed on Zarev's expertise, noting his long waiting list and the high quality of his work, with one surgery per week and a focus on individual patient care.

      community Anyone who is not taking fin after hair transplant, how is you hair now?

      in Transplants  81 upvotes 2 years ago
      The conversation is about the effectiveness of finasteride (fin) in preventing hair loss after a hair transplant. Some users have experienced hair thinning and loss after stopping finasteride, while others have had success with finasteride and minoxidil (min) in maintaining their transplanted hair. The general consensus is that finasteride is important for younger patients to prevent further hair loss.

      community Should I invest in a scalp massager?

      in Scalp Massage  7 upvotes 3 years ago
      The user is considering adding a scalp massager to their current hair loss treatments, which include finasteride, minoxidil, pumpkin seed oil, and microneedling. They are seeking advice on whether to invest in a scalp massager or remain patient with their current regimen.

      community Does RU work? I see people buying it and reporting success, but if so why was it discontinued?

      in Treatment  3 upvotes 1 year ago
      RU58841 is a controversial hair loss treatment with mixed reviews; some users report success, often in combination with other treatments like finasteride or minoxidil, while others experience side effects like chest pain. The treatment's discontinuation is speculated to be due to patent expiration and lack of profitability, despite some users continuing to use it as part of a broader regimen.