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      community Research about RU58841 /Why it was stopped

      in Research/Science  29 upvotes 5 years ago
      RU58841 showed promise for treating androgenic alopecia but research was halted due to financial and organizational changes. There were no significant safety concerns reported in human trials.

      community Scarring Alopecia and NSAIDs?

      in Female  4 upvotes 5 years ago
      The user suspects scarring alopecia and is exploring NSAIDs and turmeric/pepper for inflammation-related hair loss, having experienced burning and thinning with finasteride and testosterone reduction. They are seeking feedback while unable to afford a dermatologist.

      community Dutasteride High Libido. How come we don't talk about this?

      in Finasteride/Dutasteride  210 upvotes 1 year ago
      Dutasteride and finasteride can affect libido differently, with some experiencing increased libido and others decreased libido or erectile dysfunction. Dutasteride may increase testosterone levels but can also cause side effects like liver enzyme changes, while topical finasteride may have fewer sexual side effects.

      community Losing ground on 3x a week finasteride

      in Finasteride/Dutasteride  3 upvotes 5 months ago
      The user is experiencing hair loss despite using finasteride three times a week due to side effects and is considering alternatives like topical finasteride, estrogen blockers, or dutasteride. They are also interested in potential treatments like GT20029 and pyrilutamide.

      community How can my DHT be so low without Finasteride on cycle?

      in Finasteride/Dutasteride 3 weeks ago
      A user is curious why their DHT levels are not higher despite using 400mg of testosterone without finasteride, and wonders if zinc or GHK-Cu injections could be influencing this. Another user suggests that more testosterone typically leads to more DHT, but the user might be fortunate not to exceed normal DHT levels.

      community Lowering scalp prolactine - Any ideas ?

      in Treatment  2 upvotes 2 years ago
      The conversation is about finding the best method to lower scalp prolactine, with suggestions like P5P and Melatonin. The user also mentions HMI115 as a potential treatment and seeks feedback from those who have tried these methods.

      community Switch from fin to dut and its worse

      in Finasteride/Dutasteride  4 upvotes 1 year ago
      Switching from finasteride to dutasteride can worsen hair loss for some men due to increased testosterone levels. Topical treatments like RU58841 and Pyrilutamide are suggested to counteract these effects, but individual responses vary.

      community Pyrilutamide - Worth it if can’t use Fin?

      in Research/Science  4 upvotes 1 year ago
      Pyrilutamide is being discussed as an alternative for those who can't use finasteride, but users report it may be ineffective at low concentrations. Some users are combining it with minoxidil, microneedling, and other treatments, but results vary.

      community OND-1 "Cyclosporine A” New hair loss treatment

      in Research/Science  28 upvotes 1 month ago
      Orient Bio is developing a PLGA formulated version of Cyclosporine A to stimulate hair growth without its immunosuppressant effects. Users discuss various treatments like Clascoterone, PP405, minoxidil, and tacrolimus, expressing hope for new developments and sharing personal experiences with these treatments.

      community 5% minoxidil &1mg finasteride -7th months- Asian-23M

      in Progress Pictures  620 upvotes 2 years ago
      A user's successful hair regrowth after 7 months of using 5% minoxidil, 1mg finasteride, and adding micro needling 4 months ago. The user also took biotin, fish oil, and collagen supplements, and reduced finasteride intake to once every 3 days due to minor libido decay.

      community Alfatradiol causing shedding ?

      in Treatment  1 upvotes 1 year ago
      The user experienced a sudden decrease in hair density after starting alfatradiol while already using finasteride. Another user mentioned that initial shedding can occur with hair loss treatments, but it may not last long.

      community Anyone else just waiting until the real pyrilutamide and then GT20029?

      in Chat  5 upvotes 2 years ago
      The user is hesitant to use finasteride due to potential hormonal side effects and is waiting for the release of pyrilutamide, a new hair loss treatment. Other users suggest trying finasteride, warning about potential regret if hair loss progresses in the meantime.

      community Ultimate Non-5AR (fin/dut) stack?

      in Treatment  1 upvotes 1 year ago
      The conversation discusses alternatives to 5AR inhibitors for hair loss treatment, suggesting options like minoxidil, KX-826, pyrilutimide, microneedling, and topical bicalutamide. Concerns about side effects and the effectiveness of these treatments are also highlighted.

      community Dutasteride for trans men? (Topical vs oral?)

      in Transgender 1 year ago
      The conversation discusses using dutasteride, both topical and oral, for hair loss in trans men, considering potential side effects like depression and libido issues. The user is exploring options including topical solutions with minoxidil, retinoic acid, and hydrocortisone, and plans to start microneedling.

      community Possibilities without Fin/Dut ?

      in Treatment  4 upvotes 3 months ago
      The user experiences severe side effects from finasteride and dutasteride, including low libido and anxiety, and is currently using oral minoxidil despite shortness of breath. They are seeking alternative treatments for hair loss, having tried pyrilutamide, fluridil, and RU58841 with no success, and are considering future treatments or a hair transplant.

      community How much DHT causes hair loss ?

      in Finasteride/Dutasteride  2 upvotes 7 months ago
      The user is taking 2.5 mg dutasteride and 5% minoxidil but is not seeing hair regrowth, and is considering adding RU58841. They are experiencing fatigue and low MCV/MCH, possibly related to dutasteride, and are advised to be patient, consider microneedling, and check for iron deficiency.

      community Does taking finastride affect height at 17

      in Finasteride  116 upvotes 7 months ago
      Finasteride is being used by a 17-year-old concerned about its impact on height while still growing. The user has been balding since age 13 and was recently diagnosed with androgenetic alopecia.