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      community Topical finasteride carrier/vehicle

      in Finasteride  135 upvotes 1 year ago
      The user is considering making a homemade topical finasteride solution using an ethanol-based carrier. They are inquiring if a solution containing partially denatured ethyl alcohol and benzalkonium chloride is suitable.

      community Kintor Pharma Announces Positive Top-line U.S. Phase I Trial Results of GT20029, the World’s First Topical Use PROTAC Compound

      in Research/Science  127 upvotes 3 years ago
      The conversation discusses positive initial trial results for GT20029, a topical compound for hair loss that degrades androgen receptors, potentially requiring only weekly application. Participants express hope for this treatment to be more effective and convenient than current options like Minoxidil, Finasteride, and RU58841.

      community Welp - pp405 conference showed nothing

      in Update  79 upvotes 2 weeks ago
      PP405 shows potential for hair growth by increasing terminal hair and converting vellus hairs, but results are modest and more waiting is needed. It complements existing treatments like minoxidil and finasteride, but won't replace them.

      community Prepare to be disappointed by PP405

      in Research/Science  23 upvotes 2 months ago
      Delayed release oral minoxidil is seen as a promising advancement for hair loss treatment, offering safer, higher doses and more consistent hair follicle stimulation compared to current options. However, it is not expected to replace finasteride or dutasteride, as it does not prevent androgenetic alopecia.

      community Thoughts on Latanoprost For Miniturization?

      in Treatment  3 upvotes 3 years ago
      User discusses Latanoprost as potential hair loss treatment and considers combining it with oral minoxidil for better results. Seeking opinions on effectiveness and expense.

      community PP405 - A True Breakthrough or Another Disappointment?

      in Research/Science  32 upvotes 9 months ago
      PP405 shows potential for hair growth, with 31% of advanced balding men experiencing over 20% increase in hair density in 8 weeks. However, skepticism persists due to selective data presentation and lack of long-term results, with comparisons to treatments like minoxidil and finasteride.

      community Any users of Latanoprost/Bimatoprost?

      in Research/Science  1 upvotes 1 year ago
      The conversation is about using Latanoprost 0.01% solution for hair loss and seeking success stories. It mentions that Latanoprost works differently from Minoxidil, Finasteride, and RU58841.

      community Where to buy Latanaprost or equivalent?

      in Treatment  2 upvotes 6 months ago
      The conversation discusses using Latanoprost for hair regrowth, with the original poster seeking advice on where to purchase it without a prescription. Users suggest alternatives like Triple Hair's TH-07, which includes Finasteride, Minoxidil, and Latanoprost, and Strut's Latanoprost with melatonin and caffeine.

      community Approve PP405 quickly you coward

      in Satire  193 upvotes 9 months ago
      Pelage Pharmaceuticals is developing PP405, a topical treatment for hair growth, currently in Phase 2a trials. There is skepticism about the company's claims, and no fast-tracking approval timeline has been detailed.

      community I wrote a poem about pp405 (potential treatment)

      in Satire  19 upvotes 1 year ago
      A poem humorously suggests hope for a new hair loss treatment, PP405, while users debate the effectiveness and side effects of current treatments like Finasteride. Concerns are raised about Finasteride's side effects, especially for young users, and skepticism about new treatments is expressed.

      community Anyone used Topical Calcipotriol (cream) or VPA ( Valproic Acid)

      in Chat  7 upvotes 5 years ago
      The conversation discusses using topical Calcipotriol and Valproic Acid for hair loss, focusing on their mechanisms involving the VDR receptor and Wnt/beta-catenin pathway. Specific treatments mentioned are Minoxidil, Finasteride, and RU58841.

      community which is better ; minoxidil with more alcohol or more pg?

      in Minoxidil  5 upvotes 3 years ago
      The conversation is about the effectiveness of Minoxidil formulations with different alcohol and propylene glycol (pg) ratios. The user finds that a formulation with 20% pg and 80% ethanol dries faster but is concerned about absorption time.

      community Saw Palmetto/Pumkin seed gives basically same results as Fin

      in Treatment 1 year ago
      A user reported that Procerin, containing Saw Palmetto and Pumpkin seed oil, provided similar hair thickening results as finasteride but with milder side effects. They experienced reduced libido and watery ejaculations but are adjusting the dose to minimize these effects.

      community Groundbreaking complete hair regrowth wonder drug found!!!

      in Satire  914 upvotes 9 months ago
      A satirical post humorously discusses a fictional hair regrowth drug called PP405, with users joking about its effectiveness and bizarre presentation. The conversation includes humorous reactions and references to the absurdity of the content.

      community Will pp405 have to be inserted rectally for full benefits?

      in Transgender  32 upvotes 4 months ago
      Pp405 is discussed as a potential hair loss treatment, with humorous suggestions about rectal administration for increased effectiveness. Users joke about unconventional methods and express willingness to try anything for hair regrowth.

      community Put P5P in my shampoo, reduced itch a lot!

      in Chat  4 upvotes 3 years ago
      The user added P5P (vitamin B6) to their shampoo to reduce scalp itch, which improved significantly. They have been using finasteride for hair loss but are exploring additional treatments like topical antiandrogens and prolactin inhibitors.

      community minoxidil without propylene glycol?

      in Minoxidil  6 upvotes 1 year ago
      Minoxidil without propylene glycol is sought to avoid dermatitis, with Rogaine foam and Tecflox suggested as alternatives. Users discuss using foam to prevent irritation and suggest heating it for easier application.

      community New article on PP405..........

      in Research/Science  109 upvotes 11 months ago
      Scientists at UCLA have developed a promising treatment for male pattern baldness using a molecule called PP405, which can potentially stimulate dormant hair follicles. Initial trials showed significant results within a week, but larger clinical trials are needed to confirm its efficacy and safety.

      community Petition: Make PP405 available tomorrow instead of 2030

      in Satire  335 upvotes 9 months ago
      PP405, a promising hair loss treatment, is expected to be available by 2027, with faster trials due to its topical nature. Users are eager for its release, comparing it to existing treatments like minoxidil and finasteride, but remain cautious about its long-term effectiveness.

      community What's going on with hmi115? The Phase 2 was concluded Nov2024 but no news

      in Chat  13 upvotes 4 months ago
      Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.

      community Hot Take: Betting on PP405 can backfire

      in Research/Science  82 upvotes 9 months ago
      PP405 is seen as promising but uncertain, with users advised to continue using existing treatments like minoxidil and finasteride. Concerns include its cost, availability, and interaction with hair transplants, while some hope it could complement current treatments.

      community It looks like Pelage are giving hints that PP405 is a game changer

      in Chat  239 upvotes 2 weeks ago
      PP405 is seen as a potential breakthrough for converting vellus hairs to terminal hairs, with users expressing both hope and skepticism. It is compared to treatments like minoxidil and finasteride, with discussions on side effects and marketing concerns.

      community Any trusted sources to buy Minoxidil powder?

      in Minoxidil  2 upvotes 4 years ago
      A user is seeking trusted sources to buy Minoxidil powder to create their own solution with Propanediol. The conversation focuses on recommendations for purchasing Minoxidil powder.