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      community How to mix ru-powder with European ingredients?

      in Product  1 upvotes 2 years ago
      A user seeks advice on mixing RU58841 serum using European ingredients, specifically struggling to find propylene glycol. They are looking for alternatives to American products commonly recommended in guides.

      community What's going on with hmi115? The Phase 2 was concluded Nov2024 but no news

      in Chat  12 upvotes 6 months ago
      Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.

      community Is Latanoprost same as min/fin?

      in Satire  1 upvotes 3 years ago
      Hair loss discussion includes treatments like Minoxidil, Finasteride, and RU58841. Question asked if stopping Latanoprost causes loss of gained hair.

      community Can we get a reality check on PP405?

      in Research/Science  81 upvotes 8 months ago
      PP405 is a promising hair loss treatment that may outperform minoxidil and finasteride by reviving dormant follicles and promoting significant regrowth. Results from ongoing trials are awaited, with a potential market release between 2028-2030.

      community Any trusted sources to buy Minoxidil powder?

      in Minoxidil  2 upvotes 4 years ago
      A user is seeking trusted sources to buy Minoxidil powder to create their own solution with Propanediol. The conversation focuses on recommendations for purchasing Minoxidil powder.

      community Anyone used Topical Calcipotriol (cream) or VPA ( Valproic Acid)

      in Chat  9 upvotes 5 years ago
      The conversation discusses using topical Calcipotriol and Valproic Acid for hair loss, focusing on their mechanisms involving the VDR receptor and Wnt/beta-catenin pathway. Specific treatments mentioned are Minoxidil, Finasteride, and RU58841.

      community Looking for Latanoprost sources EU

      in Product  2 upvotes 2 years ago
      The user has been using MinoxidilMax Latanoprost 0.01% and noticed an increase in hair density after years of stability on finasteride and minoxidil. They are seeking help to find a higher dosage of Latanoprost or a reliable source to purchase the powder to make their own, without a prescription or high cost.

      community does lowering your prolactin levels regrow hair?

      in Research/Science  10 upvotes 3 years ago
      The potential of lowering prolactin levels to regrow hair, with a reference to Bayer's drug HMI 115 which has been indicated as having this effect. Treatments mentioned include Minoxidil and Finasteride, as well as RU58841.

      community Groundbreaking complete hair regrowth wonder drug found!!!

      in Satire  915 upvotes 11 months ago
      A satirical post humorously discusses a fictional hair regrowth drug called PP405, with users joking about its effectiveness and bizarre presentation. The conversation includes humorous reactions and references to the absurdity of the content.

      community Can I mix finasteride in just water for topical?

      in Finasteride/Dutasteride  5 upvotes 3 years ago
      The conversation is about whether finasteride can be mixed with just water for a topical solution and if Isopropyl Alcohol and Propylene Glycol are necessary for effectiveness and faster drying. The user is seeking advice on the formulation of topical finasteride.

      community Kintor Pharma Announces Positive Top-line U.S. Phase I Trial Results of GT20029, the World’s First Topical Use PROTAC Compound

      in Research/Science  128 upvotes 3 years ago
      The conversation discusses positive initial trial results for GT20029, a topical compound for hair loss that degrades androgen receptors, potentially requiring only weekly application. Participants express hope for this treatment to be more effective and convenient than current options like Minoxidil, Finasteride, and RU58841.

      community Finally got hold of 0.1% latanoprost

      in Treatment  7 upvotes 3 months ago
      The conversation is about a user obtaining a compounded treatment for hair loss, including 0.1% latanoprost, 0.2% melatonin, and 1% cetirizine. The user also uses 2.5 mg dutasteride, 5 mg minoxidil, and RU58841 daily, and is at Norwood 2.

      community You will lose hair if your prostaglandins aren't in balance

      in Research/Science  56 upvotes 1 year ago
      Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

      community Welp - pp405 conference showed nothing

      in Update  77 upvotes 2 months ago
      PP405 shows potential for hair growth by increasing terminal hair and converting vellus hairs, but results are modest and more waiting is needed. It complements existing treatments like minoxidil and finasteride, but won't replace them.

      community Sooo whats the consensus about pp405 now?

      in Chat  75 upvotes 2 months ago
      PP405 may help with hair regrowth, especially when combined with minoxidil and finasteride, but its long-term effectiveness is unclear. Phase 3 trials are expected to begin soon, with results in a few years.

      community Hot Take: Betting on PP405 can backfire

      in Research/Science  81 upvotes 11 months ago
      PP405 is seen as promising but uncertain, with users advised to continue using existing treatments like minoxidil and finasteride. Concerns include its cost, availability, and interaction with hair transplants, while some hope it could complement current treatments.

      community Found a slide summary for PP405

      in Research/Science  33 upvotes 2 months ago
      PP405 shows promise in stimulating new terminal hair growth by activating dormant follicles, with no systemic adverse effects observed in a short-term trial. However, long-term efficacy remains unproven, and further trials are needed to confirm its potential as a hair loss treatment.

      community Topical Finasteride Pill filler

      in Finasteride/Dutasteride  3 upvotes 4 months ago
      Users discuss making topical finasteride solutions by dissolving crushed tablets in ethanol and propylene glycol, with concerns about residue affecting effectiveness. They also mention using minoxidil and oral finasteride, noting some hair regrowth and no side effects from topical use.

      community Finasteride alternative close to fda approval in the US

      in Research/Science  57 upvotes 3 weeks ago
      Breezula, a topical treatment, is anticipated to be available in the US by mid-2027 as a potential alternative to finasteride with fewer systemic side effects. There is ongoing debate about its effectiveness and some users report similar side effects to finasteride.

      community When should we get the next news about PP405

      in Chat  25 upvotes 7 months ago
      Results for PP405 are expected next year, with concerns about its pricing and potential black market availability. Some users believe it may be slightly more effective than finasteride and dutasteride, and combining it with treatments like minoxidil and microneedling could be beneficial.