Search

for
Search:

Did you mean Prostaglandin D2?

GlossaryProstaglandin D2

lipid compound linked to hair loss and inflammation

Prostaglandin D2 (PGD2) is a type of prostaglandin, which are lipid compounds that have hormone-like effects in the body. PGD2 is involved in various physiological processes, including the regulation of inflammation and allergic responses. Notably, it has been linked to hair growth regulation, where elevated levels of PGD2 in the scalp have been associated with hair loss conditions such as androgenetic alopecia.

Related Terms

Sort by

Community Join

30 / 106 results

community Has anyone here tried topical synthetic prostaglandins (Bimatoprost, Latanoprost, cetirizine) to stimulate hair growth?

in Treatment 7 upvotes 1 year ago

The conversation discusses using topical synthetic prostaglandins like Bimatoprost, Latanoprost, and cetirizine for hair growth. The user shares a link suggesting these treatments may be effective.

community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

in Research/Science 3 upvotes 1 year ago

DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

community You will lose hair if your prostaglandins aren't in balance

in Research/Science 56 upvotes 1 year ago

Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

community Doubts about castor oil

4 upvotes 7 years ago

Castor oil's effectiveness for hair growth is debated, with concerns about its impact on skin health and prostaglandin levels. Some users suggest combining it with coconut oil and using it alongside finasteride for better results, while others recommend sticking to proven synthetic treatments.

community Mechanism of Action these drugs re-grow hair?

in Technology 2 upvotes 2 years ago

Minoxidil, finasteride, and RU58841 promote hair growth by different mechanisms, with minoxidil and prostaglandin E1 being specifically mentioned. Corticosteroids can also cause hair growth.

community Need supplemental products in addition to oral minoxidil and oral dutasteride

in Product 1 upvotes 8 months ago

The user has been using oral minoxidil and dutasteride for hair loss without success and is considering adding topical 17α-estradiol, Pyrilutamide, Clascoterone, or cetirizine. They have confirmed low serum DHT levels and are exploring additional treatments due to genetic sensitivity to DHT and prostaglandin D2.

community Castor Oil - Yay or Nay?

in Product 9 upvotes 5 years ago

The conversation discusses the potential benefits of castor oil for hair thickening, with one user noting it may increase prostaglandin E2 and decrease PGD2. The original poster plans to take 1-2ml orally daily.

community ISO a topical without minoxidil

in Finasteride/Dutasteride 3 upvotes 4 months ago

A user seeks a topical hair loss treatment without minoxidil, considering options like finasteride, dutasteride, caffeine, tretinoin, or prostaglandin analogues. Recommendations include products like Strut, Maximus, Zeuss, and custom formulas from compounding pharmacies.

community Zyrtec (Cetirizine) antihistamine for hair growth compared to Minoxidil NIH study

in Minoxidil 35 upvotes 3 years ago

The conversation discusses the potential of topical cetirizine (Zyrtec) for hair growth in comparison to minoxidil, noting cetirizine's ability to reduce prostaglandin D2, which inhibits hair growth. Users share mixed experiences with cetirizine for allergies and scalp health, and there's a mention of the risk of dementia with long-term antihistamine use.

community Chromosome 20’s balding effects and why fin likely isn’t working for some.

in Treatment 96 upvotes 8 months ago

Finasteride is effective for DHT/AR-driven hair loss but not for chromosome 20-driven cases, where treatments like minoxidil, prostaglandin analogs, and low-level laser therapy may be more beneficial. Genetic testing can help determine the underlying cause of hair loss to tailor treatment effectively.

community All Drugs in Clinical Trials in 2023

in Research/Science 71 upvotes 3 years ago

12 companies having drugs or therapies in clinical trials during 2023, with various molecules and phases of trial; the probability that some may fail; and progress being made in the field.

community High Dose Niacin Update

in Update 5 upvotes 8 years ago

High dose niacin (1000mg daily) seems to have halted hair loss but did not regrow lost hair. The user plans to continue due to additional benefits like lower stress and higher good cholesterol.

community Interesting article links major MPB theories to western diet (and life-style)

in Research/Science 58 upvotes 1 year ago

Poor diet and lifestyle contribute to male pattern baldness. Treatments like Minoxidil, dietary changes, and lifestyle adjustments may help slow hair loss.

community My dermatologist didn't give me finasteride and instead gave me latanoprost and some cream

in Treatment 7 upvotes 4 years ago

User asked dermatologist for finasteride, received latanoprost and diprogenta cream instead. Others suggest latanoprost is expensive and not better than minoxidil, recommend trying another doctor for finasteride.

community DNA test result is incredible !

in Technology 31 upvotes 4 months ago

The conversation discusses a personalized hair loss treatment plan based on DNA test results, recommending Minoxidil, Dutasteride, 17-alpha Estradiol, Cetirizine, and PRP sessions. The test identifies a high risk of hair loss due to DHT but a good response to Minoxidil, suggesting a tailored approach to treatment.

community Do you know any alternative to Minoxidil ?

in Minoxidil 2 upvotes 8 months ago

The user experienced side effects from oral minoxidil and is seeking alternatives like Stemoxydine, Aminexil, and Redensyl + Procapil. They have been using finasteride for four years and are considering other treatments due to concerns about side effects.

community Don’t Get Too Hyped About PP405. We've Seen This Movie Before.

in Research/Science 218 upvotes 11 months ago

PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.

community dunno if it's growing anything but it's making my scalp red

in Technology 182 upvotes 3 years ago

Hair loss and potential treatments, primarily focusing on Finasteride and Minoxidil. Other solutions discussed include PRP, dermarolling, LLP, and scalp tension relief.

community Finasteride gyno experience and in dire need of advice

in Finasteride/Dutasteride 7 upvotes 6 years ago

A user experienced puffy nipples and lumps from finasteride, leading to a dilemma between continuing treatment with potential surgery or accepting hair loss. They restarted finasteride at a lower dose with supplements but still face side effects and are seeking advice on whether to persist or stop.

community Does microneedling regrow hair on dormant bald regions which have been bald for many years?

in Microneedling 6 upvotes 6 years ago

Microneedling may help regrow hair in dormant bald regions by stimulating stem cell transfer. Users discuss its effectiveness and how collagen might aid in the process.

community Daily aspirin is ruining your Min. gains

in Minoxidil 6 upvotes 2 years ago

Aspirin reduces the effectiveness of minoxidil for hair loss. Quercetin and 5-ASA medications also inhibit the necessary enzyme for minoxidil to work.

community Does anyone know of the actual effectiveness of the DP2 inhibitors?

in Question 4 upvotes 8 years ago

Setipiprant and Fevipiprant are questioned for their effectiveness in hair maintenance, with skepticism due to lack of convincing results beyond vellus hair growth. The user is satisfied with Minoxidil and Finasteride but is curious about the potential of DP2 inhibitors.

community Dental technician is convinced that he has found the cause of pattern hair loss

in Research/Science 316 upvotes 1 year ago

A dental technician claims malocclusion causes pattern hair loss due to poor scalp circulation. Users debate this, noting treatments like finasteride, minoxidil, and microneedling focus on DHT and blood flow.

community For those of you who are getting facial skin side effects (aging, dark circles) from minoxidil, try this, it helped me.

in Minoxidil 10 upvotes 5 years ago

The conversation provides tips to reduce facial skin side effects from Minoxidil, such as changing pillowcases, sleeping on the back, careful application, hydration, and taking breaks. One reply suggests that alcohol in Minoxidil formulations, not Minoxidil itself, may cause skin aging.

community 30-Min Dermatology Visit – Best Questions to Ask About Balding? ( 175$ )

in Treatment 6 upvotes 1 year ago

The conversation discusses hair loss treatments, focusing on finasteride, minoxidil, and other options like PRP and ketoconazole. It highlights the importance of asking specific questions during a dermatology visit to determine the cause of hair loss and appropriate treatments.

community Pyrilutamide Phase 2 Results Release Date: June 2022

in Research/Science 111 upvotes 4 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. Pyrilutamide Phase 2 results are expected in June 2022, with hopes for a better alternative to current treatments.

community Starting With "Strut" Topical: Dut %0.1 + Min %7.5 + Tretinoin %0.0125 + Biotin (and more)

in Treatment 8 upvotes 4 years ago

The user started a hair loss treatment with a topical solution containing 0.1% Dutasteride, 7.5% Minoxidil, 0.0125% Tretinoin, and Biotin, along with a multivitamin, Ashwagandha, CBD oil, Retinol, and Caffeine Solution. They experienced some shedding and scalp irritation, leading to a reduction in the use of the caffeine solution.

community M22 Minoxidil twice daily on the temples for 7 months, Finasteride 0.5 mg ed for 3 months

in Progress Pictures 115 upvotes 1 year ago

Minoxidil helped with temple regrowth, and finasteride improved overall hair appearance and stopped further hair loss. Minoxidil was also applied to eyebrows and eyelids, with noticeable gains, but was stopped on the beard due to bloating.

community Min/Fin 3 months difference - 23yo dude

in Progress Pictures 526 upvotes 10 months ago

A 23-year-old experienced significant hair regrowth in 3 months using a topical mixture of minoxidil 5% and finasteride 1%, with added bimatoprost. The treatment is government-subsidized, costing around $15, and the user reported no side effects.

community I had claude create a protocol only using fda approved drugs.

in Research/Science 4 upvotes 4 months ago

A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.