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      community My scalp punch biopsy results🤔?

      in Female  8 upvotes 3 years ago
      Female using Rogaine foam for hair loss had scalp punch biopsy, diagnosed with Androgenetic Alopecia (AGA). Doctor recommended starting Spironolactone 50mg.

      community RU58841 has gotten rid of my acne

      in Product  1 upvotes 10 months ago
      RU58841, combined with 5% minoxidil, helped reduce acne and hair loss. Users discussed using RU58841 cream for acne and shared experiences with other treatments like finasteride and dutasteride.

      community Setipiprant trial results

      in Update  10 upvotes 7 years ago
      Setipiprant trial for hair loss failed, showing no difference between placebo and treatment. Discussion also noted placebo users reporting side effects.

      community 22M Dut+min+microneedling. Diffuse AGA.

      in Progress Pictures  19 upvotes 4 months ago
      A 22-year-old male uses dutasteride, a serum with 10% minoxidil and 0.5% finasteride, and microneedling for diffuse androgenetic alopecia. Progress pictures show changes from July 2025 to February 2026.

      community Breaking hair loss news! GT20029 is a resounding success!

      in Product  132 upvotes 2 years ago
      GT20029, a new hair loss treatment, shows promising results but only a slight improvement over placebo. People are cautiously optimistic, discussing its potential and combining it with existing treatments like Minoxidil and Finasteride.

      community Would RU58841 work on a test cycle?

      in Technology  1 upvotes 1 year ago
      OP experienced side effects from finasteride and is considering using RU58841 to prevent hair loss during a testosterone cycle. They have also used minoxidil, Nizoral, alfatradiol, and fluridil successfully.

      community The MPB itch aka DHT itch is very real.

      in Chat  9 upvotes 3 years ago
      Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

      community Need supplemental products in addition to oral minoxidil and oral dutasteride

      in Product  1 upvotes 9 months ago
      The user has been using oral minoxidil and dutasteride for hair loss without success and is considering adding topical 17α-estradiol, Pyrilutamide, Clascoterone, or cetirizine. They have confirmed low serum DHT levels and are exploring additional treatments due to genetic sensitivity to DHT and prostaglandin D2.

      community Pyrilutamide Phase 3 on its way

      in Treatment  128 upvotes 4 years ago
      Pyrilutamide Phase 3 approved, starting early 2022 with 416 subjects for 24 weeks. Drug potentially better than RU and Breezula, with some users reporting no side effects.

      community Creatine and ru-58841 experiences?

      in Chat  1 upvotes 9 months ago
      RU58841 is preferred over finasteride for blocking DHT on the scalp, especially for those with aggressive MPB. Creatine is associated with increased hair shedding, even when using RU58841.

      community Trestolone (MENT) as a nuclear treatment

      in Treatment  99 upvotes 3 years ago
      Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

      community TrichoGene minoxidil response test?

      in Minoxidil 3 years ago
      The conversation is about the legitimacy and affordability of ordering a Minoxidil response test from TrichoGene, an India-based company, as an alternative to Daniel Alain. The user is seeking feedback on whether TrichoGene is a reliable option.

      community Ru58841 ruined my life. Here’s why.

      in Product  130 upvotes 4 years ago
      User experienced shortness of breath, high blood pressure, red eyes, and eye floaters after using RU58841 for hair loss. They warn others to avoid RU58841 and stick to finasteride, minoxidil, and dutasteride.

      community Purchasing and Shipping Alpecin DMG to the United States.

      in Product  3 upvotes 9 months ago
      A user is seeking help to purchase and ship Alpecin DMG to the United States due to issues with eBay sellers. They prefer Alpecin DMG over minoxidil because of concerns about minoxidil's effects on insulin production, as they have diabetes.

      community Has anybody tried RU58841 and pyrilutamide together?

      in Chat  10 upvotes 11 months ago
      RU58841 and pyrilutamide are being discussed as potential hair loss treatments, with some users reporting side effects. There is interest in these treatments as alternatives to 5ar inhibitors and oral minoxidil due to concerns about safety and side effects.

      community By when would pp405 be available in the grey market?

      in Chat  15 upvotes 3 months ago
      PP405 might take 3-4 years to be available, but some claim Everychem offers a similar product, though its effectiveness is debated. Users discuss the risks of using untested grey market products and the potential for adverse effects.

      community How long do you keep ru-58841 on?

      in Product  1 upvotes 8 months ago
      The conversation discusses the application of RU58841 for hair loss, with the user applying 1.75 mg at 5% concentration for half an hour daily. The user mentions managing seborrheic dermatitis while using this treatment.

      community What is the cause of "DHT itch"?

      in Research/Science  7 upvotes 1 year ago
      The conversation discusses the effects of using Tongkat ali and dioscorea to raise DHT levels, leading to increased body hair growth and an itchy scalp, without causing hair loss. The discussion also debates the role of DHT in male characteristics and its impact on sexual function, with differing opinions on its importance and effects.

      community Thinking about using PP405 and RU58841

      in Research/Science  1 upvotes 5 months ago
      The conversation is about a person using dutasteride and minoxidil for hair loss, considering adding RU58841 and PP405 for more density. They are seeking advice on using these treatments and exploring other options like GT20029.

      community RU 58841 or do I go for Nizoral shampoo instead? Have curly hair

      in Ketoconazole  1 upvotes 10 months ago
      The user is considering whether to add RU58841 or Nizoral shampoo to their current hair loss treatment of finasteride and minoxidil, noting budget constraints and concerns about hair dryness. They are unsure if RU58841 is worth adding or if they should use both treatments to see the effects.

      community Alpha plus from Anagenica - 25%CB???

      in Product  2 upvotes 2 years ago
      A user ordered Alpha Plus from Anagenica, expecting it to contain specific percentages of Fin, Estradiol, Minoxidil, and CB0301. However, the received product's label showed different percentages, including a surprising 25% CB, leading the user to question its safety and accuracy.

      community The amazing fast pace of PP405.

      in Chat  327 upvotes 8 months ago
      PP405 is a new hair loss treatment advancing quickly in trials, generating excitement and skepticism about its effectiveness and marketing claims. Some see it as a potential alternative to minoxidil and finasteride, but concerns about long-term effects and the need for DHT blockers persist.

      community Androgen degraders for hair loss

      in Research/Science  61 upvotes 1 year ago
      The conversation discusses androgen receptor degraders for hair loss, highlighting their potential advantages over traditional AR blockers like RU58841 and pyrilutamide. Concerns about the safety and cost of these treatments are also mentioned.