A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.
A user experimenting with an extreme hair loss treatment stack of Dutasteride, RU58841, 15 mg oral minoxidil, and microneedling, which sparked a debate among other users about the safety of this approach.
User shared 4.5-month hair loss treatment results using Fin, Minoxidil, and microneedling. Others discussed postponing hair transplant and adjusting microneedling depth.
Hair loss treatments discussed include dermarolling, minoxidil, finasteride, and RU58841. Some users find dermarolling sad, while others mention the complexity of biological systems and limited research funding for hair loss.
The conversation discusses the lack of significant advancements in hair loss treatments since the introduction of finasteride 22 years ago, with many expressing frustration over the failure of new projects and skepticism about future developments. Some users mention hair transplants and other potential alternatives like Alfatradiol and Fluridil, but acknowledge finasteride's dominance in the market due to its effectiveness and affordability.
A new hair loss treatment theory beyond minoxidil and finasteride is proposed, causing mixed reactions in the community, with some members eager to explore and support it, while others call for more research and evidence.
Cutting sugar may not significantly impact hair loss, as DHT and androgen receptors are the main issues. Effective treatments include finasteride, dutasteride, RU58841, and minoxidil, often combined with microneedling.
A new hair loss lotion by Dr. Brotzu, expected to regrow up to 5 years of lost hair, is set to be released by Fidia Farmaceutici. It claims to work like minoxidil and finasteride without side effects, but skepticism exists due to its classification as a cosmetic product.
The user is exploring hair growth stimulants other than Minoxidil, mentioning Stemoxydine, various peptides, drugs like Latanoprost and Bimatoprost, and natural remedies such as Rosemary Oil and Caffeine. They express concerns about the long-term effectiveness and safety of these alternatives and seek more information on viable options for hair regrowth.
The conversation discusses hair regrowth treatments using finasteride, minoxidil pills, and topical minoxidil, with a focus on the use of a 1.5mm derma roller. Users advise caution with derma rolling, suggesting smaller needle sizes and longer intervals between sessions to avoid skin damage and systemic absorption of minoxidil.
Creatine is unlikely to worsen hair loss for those on finasteride, with no strong scientific evidence linking it to increased hair loss. Many users report no negative effects on hair while using creatine.
The user has maintained hair thickness using oral finasteride and minoxidil for four years, with suggestions to consider dutasteride or a hair transplant for further improvement. Some users recommend trying topical minoxidil with tretinoin or increasing the oral minoxidil dose for better results.
The conversation is about hair loss treatments, specifically using dutasteride and oral minoxidil, and exploring additional vitamins and supplements like vitamin D, zinc, biotin, and omega-3 to support hair health. Users suggest getting a blood panel to identify deficiencies and emphasize the importance of protein and overall nutrition.
Hair loss treatments have not advanced since 2018, with finasteride, minoxidil, and RU58841 still being the main options. A permanent cure is unlikely due to the profitability of ongoing treatments.
Successful hair regrowth after six months using finasteride and topical minoxidil, with minimal side effects like anxiety. Finasteride was the main treatment, and minoxidil supported regrowth.
The conversation is about using a dermastamp for hair loss treatment and concerns about a potentially scam product, pp405. It suggests sticking with known treatments like finasteride and minoxidil.
Hair cloning technology is advancing, with clinical trials for improved methods expected by 2028 and 2029, potentially offering a solution for hair loss if donor follicles remain. Organtech's expansion into other biotech areas may secure funding, but the effectiveness of cloning depends on the availability of androgen-resistant donor follicles.
PP405 shows significantly better early-stage hair regrowth results compared to minoxidil and finasteride, with 31% of users experiencing over 20% density increase in 4–8 weeks. Minoxidil and finasteride show minimal or no visible regrowth in the same timeframe.
PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.
A user has been using minoxidil and finasteride for hair loss for about five years, noticing that while it hasn't improved much, it has slowed hair loss. They recently added topical retinol, which seems to have increased hair growth, possibly by enhancing minoxidil absorption and activity.
Creatine may worsen hair loss in some, especially with androgenic alopecia, but evidence is mixed. Some users experience no hair loss when using creatine with minoxidil and finasteride, while others notice increased shedding.
Tretinoin is used with minoxidil to enhance hair growth, with some users applying tretinoin before minoxidil to improve results. Some users report success with this combination, while others experience irritation or dryness.
A user experienced a hard lump under their nipple and increased hair loss after four months of finasteride. They are concerned about the lump and plan to stop the treatment.
Brian Dye's theory links skeletal malocclusion type II to hair loss, suggesting it's a blood flow issue. Treatments mentioned include minoxidil, finasteride, and anti-inflammatory drugs like benaxoprofen.
A 25-year-old with AGA experienced hair thinning and dandruff, stabilized with topical finasteride and minoxidil but saw minimal regrowth. They seek advice on styling and consider oral minoxidil and microneedling for denser hair.
Hair growth can be induced without stopping DHT, as seen with Minoxidil. HMI115 may work by promoting follicle growth, not targeting the root cause of hair loss (DHT).
Creatine does not significantly affect hair loss when taking finasteride. Some users report no change, while others believe it may accelerate hair loss if predisposed to male pattern baldness.