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GlossarySLC39A family

group of genes encoding proteins that transport zinc into cells

The SLC39A family refers to a group of genes that encode zinc transporters, which are proteins responsible for moving zinc into cells. Zinc is an essential mineral that plays a crucial role in various biological processes, including immune function, DNA synthesis, and cell division. Mutations or dysregulation in these genes can lead to various health issues, including hair loss and other disorders.

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community mallia therapeutics 8T3 scd83 molecule for ffa/lpp mainly and aga

in Technology 9 upvotes 4 months ago

A user applied the 8T3 product for hair loss, targeting LPP and AGA, and plans to update on its effectiveness. The product uses a saline buffered phosphate vehicle, suitable for those intolerant to ethanolic vehicles.

community How to source winlevi? Not generica

in Product 1 upvotes 1 month ago

The conversation is about sourcing Winlevi (clascoterone) for personal use in the EU. The user is specifically looking for a non-generic version.

community Winlevi (clascoterone 1%) anyone trying it

in Treatment 2 upvotes 5 months ago

Winlevi (clascoterone 1%) is being discussed as a potential hair loss treatment. Users are considering its use despite concerns about its delivery method.

community PP405 is NOT gray market jxl069

in Technology 26 upvotes 4 months ago

PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

community Clascoterone - clearnet vendor

in Chat 2 upvotes 5 months ago

The conversation is about finding a clearnet vendor for clascoterone, also known as Winlevi, for hair loss treatment. The user is seeking recommendations via direct message.

community Best Treatment In The Pipeline?

in Chat 15 upvotes 1 year ago

New treatments for AGA are emerging, including pyrilutumide, gt0029, scube3, kx-826, and pp405. Verteporfin is mentioned as a promising option.

community Expectations control for SCUBE3

in Research/Science 22 upvotes 2 years ago

SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

community cb-03-01 research chem (winlevi/clascoterone cream)

in Technology 3 upvotes 2 years ago

The user is considering using CB or clascoterone for hair loss, potentially as an alternative to RU. They're also contemplating asking a dermatologist for topical clascoterone cream to apply to their temple.

community does anybody have winlevi clascoterone yet?

in Finasteride/Dutasteride 6 upvotes 5 years ago

The conversation is about hair loss treatments, specifically discussing the use of Minoxidil, Finasteride, and RU58841. A user inquired about the availability of Winlevi (clascoterone) for hair loss.

community SCUBE 3 (the last hair bender)

in Research/Science 2 upvotes 11 months ago

SCUBE3 and Amplifica's progress in hair loss treatment is being discussed, with inquiries about their current status and clinical trials. No specific updates or new information are provided in the conversation.

community Winlevi just got FDA approval, projected to be available early 2021 in the US

in Treatment 43 upvotes 5 years ago

The conversation is about creating a higher concentration of the newly FDA-approved hair loss treatment, Clascoterone (Winlevi), through compounding pharmacies and possibly organizing group purchases. Some users are unfamiliar with Winlevi and are asking for an explanation of the drug.

community Chinese source for pyrilutamide or ru8841 ?

in Product 3 upvotes 8 months ago

The conversation is about finding a reliable Chinese source for pyrilutamide or RU58841, ideally with a third-party Certificate of Analysis from Janoshik Analytical. The user is seeking recommendations for these hair loss treatments.

community Why there are no updates from Amplifica about SCUBE3 & AMP-303?

in Research/Science 6 upvotes 8 months ago

Amplifica has not provided updates on SCUBE3 and AMP-303, raising concerns about their trial outcomes. Users also mention other treatments like Minoxidil, finasteride, RU58841, PP405, and ET-03.

community Has anyone tried Winlevi (a.k.a. Clascoterone or CB-03-01) on their scalp yet?

in Treatment 9 upvotes 4 years ago

The acne medication Winlevi, which contains Clascoterone, is available in the U.S. and may slow down hair loss until a higher concentration treatment, Breezula, is released.

community Using WinLevi (Clascoterone) for Seborrheic Dermatitis and Acne

in Treatment 4 upvotes 2 years ago

Winlevi (clascoterone) is discussed as a treatment for hormonal acne and seborrheic dermatitis due to its ability to block DHT and regulate sebum production. The post suggests that Winlevi could offer a novel approach for managing seborrheic dermatitis.

community SUBE3 for sale in the gray market?

in Chat 4 upvotes 1 year ago

SCUBE3 is available online but poses risks like tumor promotion and high costs. Users advise against using it due to health concerns and inefficacy as a standalone treatment.

community What are we thinking about this SCUBE3 boys

in Product 7 upvotes 8 months ago

SCUBE3 is a promising new molecule that can restart hair growth by reawakening dormant hair follicles. Users express skepticism about its availability timeline, with some hoping for release by 2026.

community Pyrilutamide from Hairlisciously? Other suppliers?

in Treatment 8 upvotes 3 years ago

The conversation is about the effectiveness and trustworthiness of Pyrilutamide hair loss treatment sold by Hairlisciously, with concerns about product purity and a request for alternative suppliers. No specific treatments were confirmed to be used by participants.

community reminder: Pyrilutamide 0.9% (kx-826) ships to Europe from Amazon US and Koshinemall

in Product 9 upvotes 1 year ago

Pyrilutamide 0.9% (kx-826) is available for shipping to Europe from Amazon US and Koshinemall. Shipping costs and availability vary between the two shops.

community Anyone have an alternative solvent for pyrilutamide??

in Product 2 upvotes 2 years ago

The user is seeking an alternative solvent for pyrilutamide due to skin irritation from ethanol and propylene glycol. They experienced similar issues with topical minoxidil.

community Sodium Laureth Sulfate (SLS) in shampoos

4 upvotes 10 years ago

Sodium Laureth Sulfate (SLS) in shampoos and its potential impact on thinning hair. The user follows a regimen of shampoo, keto shampoo, and conditioner, seeking suggestions for better products.

community JXL082 is not PP405 and Everychem followed the wrong lead

in Research/Science 43 upvotes 10 months ago

JXL082 is not the same as PP405, leading to a halt in sales and a plan to synthesize the real PP405. There is skepticism about the safety and effectiveness of JXL082 and PP405, with concerns about patent issues and the long-term impact on hair growth.

community KX-826 (Pyrilutamide) on Amazon

in Treatment 9 upvotes 1 year ago

The conversation is about purchasing KX-826 (Pyrilutamide) on Amazon, now called Koshine. A user mentioned their order is expected to arrive between August 22 and September 13.

community Pyrilutamide vs enzalutamide. Same thing?( Especially for biochemists, farmacologists)

in Research/Science 17 upvotes 3 years ago

Researching whether pyri and enza, which are stereoisomers of each other, share the same features related to CNS penetration/GABA Inhibition; safety and efficacy when used topically at 0.5-1%; and cost comparison between the two treatments.

community Ligand Chem cease trading Pyrilutamide

in Product 14 upvotes 3 years ago

Pyrilutamide, a possible hair loss treatment, ceasing to be traded due to patent laws; and the hope that this indicates it may be a legitimate treatment.

community gt20029 any u-lab order possible?

in Product 8 upvotes 1 year ago

The user is seeking alternative hair loss treatments due to side effects from finasteride and minoxidil. They are inquiring about the availability of gt20029 from u-lab.

community pyrilutamide log from someone who couldnt take fin/min/ru due to sideeffects

in Progress Pictures 105 upvotes 3 years ago

A user (seblt) who has had side effects from finasteride, minoxidil and RU58841 but is now trying pyrilutamide as a last resort, with other users providing advice and support. They have already seen some baby hairs growing after 10-14 days of treatment and will provide updates in 1-2 weeks.

community Ru58841 and pyrilutamid receptor binding affinity vs spironolactone?

in Female 6 upvotes 3 years ago

Female considering adding topical anti-androgen, seeks advice on RU58841 or pyrilutamid's binding affinity compared to spironolactone.

community Other sulfurtransferase activity upregulator other than Tretinoin?

in Minoxidil 8 upvotes 2 years ago

The user does not respond well to minoxidil and is seeking an alternative to Tretinoin to upregulate sulfurtransferase activity for hair loss treatment. No specific alternative treatments were mentioned.

community Pyrilutamide binding affinity is similar to RU

in Research/Science 16 upvotes 3 years ago

Comparing the effectiveness of RU58841, Pyrilutamide and CB-03-01 as treatments for hair loss, with people discussing different aspects such as binding affinity, time of inhibition, safety data and cost.