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GlossaryCYP3A5

gene encoding an enzyme that metabolizes drugs in the liver

CYP3A5 is a gene that encodes an enzyme belonging to the cytochrome P450 family, which is involved in the metabolism of various drugs and toxins in the liver. This enzyme helps break down medications and other substances, affecting how they are processed in the body. Variations in the CYP3A5 gene can influence an individual's response to certain drugs, making it important for personalized medicine.

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CYP3A5 Polymorphism in Circulating Tumor Cells Confers an Increased Disease-Free Survival in DLBCL Patients Treated with R-CHOP

research CYP3A5 Polymorphism in Circulating Tumor Cells Confers an Increased Disease-Free Survival in DLBCL Patients Treated with R-CHOP

March 2025 in “OncoTargets and Therapy”

A specific genetic trait in tumor cells is linked to longer survival without disease in certain lymphoma patients.

A Population Pharmacokinetic Model for Individualized Regimens of Finasteride According to CYP3A5 Genotype and Liver Function

research A population pharmacokinetic model for individualized regimens of finasteride according to CYP3A5 genotype and liver function

October 2023 in “Journal of pharmaceutical investigation”

Finasteride dosages should be adjusted based on CYP3A5 genotype and liver function to avoid side effects.

research Pilot study: genetic distribution of AR, FGF5, SULT1A1 and CYP3A5 polymorphisms in male Mexican population with androgenetic alopecia.

January 2022 in “PubMed”

Certain genetic variations are linked to hair loss in Mexican men.

Matters of the HAART: Ritonavir Induced CYP3A4 Inhibition of Intranasal Fluticasone Leading to Cushing's Syndrome

research SAT340 Matters Of The HAART - Ritonavir Induced CYP3A4 Inhibition of Intranasal Fluticasone Leading To Cushing’s Syndrome

1 citations , October 2023 in “Journal of the Endocrine Society”

HIV medication ritonavir can increase the effects of nasal sprays like fluticasone, causing Cushing's syndrome.

research Effect of a Benign Prostatic Hyperplasia (BPH) Xenobiotic - Croton membranaceus Müll.Arg. Root Extract on CYP1A2, CYP3A4, CYP2D6, and GSTM1 Drug Metabolizing Enzymes in Rat Model

1 citations , August 2020

Croton membranaceus root extract can change how drugs are processed in the body.

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