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      community where does the renewed spironolactone hype come from?

      in Research/Science  8 upvotes 3 years ago
      Topical spironolactone is gaining attention as an alternative hair loss treatment, but it's not as effective as other options like finasteride. Oral spironolactone can cause side effects in men, and there are better topical alternatives like RU, Pyril, and CB.

      community Anybody else have family in denial over your hair loss?

      in Chat  75 upvotes 1 year ago
      A 20-year-old discusses family denial about his hair loss, diagnosed with seborrheic dermatitis, folliculitis, and male pattern baldness. He is prescribed Dutasteride and oral Minoxidil for treatment.

      community Regression report from 2017 to 2025

      in Progress Pictures  121 upvotes 3 months ago
      The user stopped finasteride for family planning but plans to restart it and is considering dutasteride. Users discuss the safety of finasteride during family planning, with some sharing experiences of having healthy children while on the medication.

      community Concerns about CosmeRNA safety mechanisms

      in Treatment  3 upvotes 3 years ago
      Concerns about CosmeRNA safety mechanisms and potential side effects. Discussion includes comparisons to Fluridil and questions about nanoparticle specificity and siRNA stability.

      community We are actually in the year 2026..

      in Satire  34 upvotes 1 month ago
      People are frustrated with the lack of new hair loss treatments stronger than minoxidil and finasteride. Some are using dutasteride to maintain hair while hoping for future solutions.

      community When do you think Breezula will be released to the public?

      in Chat  32 upvotes 4 years ago
      The conversation discusses expectations for the release of Breezula, a new hair loss treatment, and compares it to existing treatments like finasteride. Some believe Breezula could be a game-changer due to fewer side effects, while others await more permanent solutions like hair follicle cloning.

      community Hot Take: Betting on PP405 can backfire

      in Research/Science  81 upvotes 1 year ago
      PP405 is seen as promising but uncertain, with users advised to continue using existing treatments like minoxidil and finasteride. Concerns include its cost, availability, and interaction with hair transplants, while some hope it could complement current treatments.

      community I wish pp405 work and i have full head of hair in 2028-2030

      in Chat  106 upvotes 8 months ago
      People are hopeful about future hair loss treatments like PP405, GT20029, and VDPHL01, while some are currently using finasteride and minoxidil. There is skepticism about the effectiveness of new treatments, and some advise against hair transplants until more promising drugs are available.
      M30. thoughts onswitching from oral to topical

      community M30. thoughts onswitching from oral to topical

      in General  67 upvotes 6 months ago
      A user is considering switching from oral to topical treatments for hair loss due to side effects like watery semen and erectile dysfunction. They are currently using oral finasteride and minoxidil and are concerned about potential sexual side effects with topical use.

      community Balding turned me into a Norwood mentalist

      in Chat  253 upvotes 2 years ago
      The conversation revolves around how balding has made the original poster and others hyper-aware of other men's hairlines, often judging the severity of their hair loss and whether they've had treatments like hair transplants, minoxidil, or finasteride. Some participants express a need for therapy due to their obsession, while others joke about their newfound "expertise" in assessing hair loss.

      community 21 months on topical minoxidil and full HRT

      in Transgender  214 upvotes 2 years ago
      The conversation is about a transgender individual's experience with hair regrowth using topical minoxidil and hormone replacement therapy (HRT), expressing concern about the slow growth and thin appearance of their hair. Some responses encourage patience and highlight the variability of results, while others discuss the role of HRT and its effects.

      community A positive thought rolling into Christmas

      in Research/Science  12 upvotes 6 months ago
      The conversation is optimistic about future hair loss treatments, highlighting Veradermics, Breezula, and PP405 as promising options expected by 2027-2028. The user expresses hope that these developments will prevent future generations from experiencing the same struggles with hair loss.

      community Am i the only one in here that doesnt?

      in Chat 3 years ago
      The insecurity people feel when going to the barber for a haircut due to visible hair loss. Replies include encouragement, advice such as looking for more understanding barbers and female hairdressers, as well as suggestions of trying at-home haircuts or using treatments like minoxidil, finasteride, and RU58841.

      community Likelihood of new treatments in the next few years?

       12 upvotes 10 years ago
      New hair loss treatments like Shiseido/Replicel and Histogen were discussed, with cautious optimism about their availability by 2018. Setipiprant, Replicel, and Bimatoprost were mentioned as potential treatments expected around 2016-2017.

      community Why is nobody talking about topical Spironolactone?

      in Chat  12 upvotes 2 months ago
      Topical spironolactone is discussed as a hair loss treatment, with concerns about its effectiveness and side effects compared to finasteride and minoxidil. Users mention its unpleasant smell, potential systemic absorption, and suggest alternatives like pyrilutamide and alfatradiol.

      community Newcomer buzzcutter

      in General  111 upvotes 11 months ago
      A 24-year-old with thinning hair and receding sides is considering using Minoxidil and finasteride to improve hair thickness. They are seeking general expectations for these treatments, acknowledging individual results may vary.

      community Who else is looking forward to full phase 2 results of PP405?

      in Chat  59 upvotes 4 months ago
      PP405 is a potential hair loss treatment showing promise, especially for men with severe balding. Some are hopeful it will be a game-changer for those who cannot tolerate finasteride or minoxidil, despite skepticism about the outcomes.

      community Further prolactin research....

      in Research/Science  6 upvotes 2 years ago
      HMI 115 did not work as expected for hair regrowth in humans, unlike in macaque monkeys. There is anticipation for further research on prolactin's role in hair loss, with expectations that pharmaceutical companies will likely solve this before universities.