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      community New angles to attack beyond DHT

      in Research/Science  4 upvotes 1 year ago
      Exploring hair loss treatments beyond DHT, including Minoxidil, pyruvate, Gt20029 targeting androgen receptors, and vasodilators. Other options like Kx826, adenosine signaling, growth factor topicals, and microneedling are also discussed.

      community 2 years of Androgen inhibition.

      in Progress Pictures  143 upvotes 9 months ago
      A 23-year-old has been using finasteride, dutasteride, and spironolactone to combat hair loss and hormonal acne, with mixed results and concerns about side effects. The user is experimenting with spironolactone despite its potential risks, hoping for skin and body hair improvements.

      community Minox experimentation on pubic hair

      in Minoxidil  280 upvotes 2 years ago
      A user applied minoxidil to their pubic hair for 3 months, resulting in hair growth over 4 inches, and is considering using it for a scalp hair transplant. They plan to continue the treatment despite their wife's disapproval.

      community min/fin results on my scalp | 19 (M)

      in Progress Pictures  95 upvotes 2 years ago
      A 19-year-old male shared progress pictures showing hair regrowth on his scalp after starting a treatment with Minoxidil and Finasteride on November 24th. He noted improved hair texture and a halt in hair shedding for the past two weeks.

      community progress from april 2024 to june 2025

      in Progress Pictures  170 upvotes 1 year ago
      The conversation is about a user's impressive hair recovery over 14 months using 0.5mg dutasteride, 5% topical minoxidil, saw palmetto shampoo, and occasional microneedling. The results are highly praised by others, with many expressing admiration and hope for similar outcomes.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  63 upvotes 2 years ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community Update after 14 months posted last September

      in Minoxidil  871 upvotes 6 months ago
      The user successfully regrew hair using 1.2mg finasteride and 3mg minoxidil daily, without a hair transplant. They experienced significant improvement over 14 months, leading to positive changes in their appearance and confidence.

      community Where is GT20029 already? Grrrr

      in Research/Science  20 upvotes 2 years ago
      The conversation is about frustration over the delay in phase 2 results for a hair loss treatment called GT20029. One user suspects the treatment may have failed.

      community bro where tf is GT20029, Q1 2024 is over already

      in Research/Science  41 upvotes 2 years ago
      The conversation discusses the delay in the release of GT20029 for hair loss treatment and skepticism about its effectiveness. Participants mention other treatments like verteporfin and advancements in transplant procedures as more realistic options.

      community This guy claims stem cells fixed his balding

      in Is this regrowth?  325 upvotes 2 years ago
      A man who claimed to have regrown his hair using stem cell treatment, sparking a debate about its effectiveness and cost. Some users suggested he might be using other treatments or substances, while others shared their own experiences with stem cell therapy for hair loss.

      community How is scalp sensitivity even measured?

      in Research/Science  9 upvotes 5 months ago
      There are no tests to determine genetic follicle sensitivity for hair loss, and conclusions are based on hypothetical or post-balding observations. Finasteride is mentioned as an easy, consistent treatment option compared to natural treatments.

      community after 4 years of balding 16-20 i have finally decided to do something about it

      in Chat  22 upvotes 1 year ago
      The conversation is about dealing with hair loss, with the original poster deciding to start using topical finasteride and minoxidil after unsuccessful PRP and Regenera treatments. Others share their experiences with hair loss, treatments, and the importance of finasteride to prevent further hair loss.

      community Anyone here used spirolactone/cyproterone acetate/bicalutamide?

      in Chat  4 upvotes 9 months ago
      The conversation discusses the use of spironolactone, cyproterone acetate, and bicalutamide for hair loss, with concerns about side effects like gynecomastia and depression. Topical spironolactone is considered safe for men and effective when combined with regular treatments.

      community Does the effect of spironolactone on androgenetic alopecia really weaken over time?

      in Female  4 upvotes 1 year ago
      Spironolactone can remain effective for a long time in treating androgenetic alopecia, but it may not completely stop hair loss. Hair loss treatments like spironolactone, finasteride, and dutasteride slow down hair loss rather than cure it, and their effectiveness can vary based on individual response and the aggressiveness of the condition.

      community Pp405 - it has to work. It has to.

      in Research/Science  170 upvotes 3 months ago
      Hair loss treatments, including PP405, minoxidil, finasteride, and RU58841, with hopes for future solutions. Participants discuss the emotional impact of hair loss and consider alternatives like hair transplants or acceptance.

      community KX-826 1% Phase II Results from China Just Dropped

      in Research/Science  37 upvotes 10 months ago
      KX-826 (Pyrilutamide) 0.5% and 1.0% solutions showed promising results in increasing hair count for male androgenetic alopecia, with the 0.5% dose slightly outperforming the 1% dose. The treatment was well-tolerated with no sexual side effects, but skepticism remains due to past inconsistencies in trial results.

      community 25 yo male progress after 9 months on Fin

      in Progress Pictures  12 upvotes 6 years ago
      A 25-year-old male saw significant hair growth in the temple regions after 9 months of using minoxidil and finasteride. He is happy with the progress but acknowledges more improvement is needed.

      community 4 months finasteride + minoxidil

      in Is this regrowth?  54 upvotes 2 months ago
      The conversation is about hair regrowth using finasteride and minoxidil, with users noting visible new hair growth and discussing dosages. Some users express encouragement and hope, while one advises against using finasteride.

      community I got a weird one you guys/gals

      in Chat  11 upvotes 1 year ago
      A 33-year-old man experienced diffuse thinning and hair shedding due to sleep deprivation and low testosterone. After starting hCG treatment, he noticed hair regrowth on his temples.
      Can’t tolerate fin, am I screwed?

      community Can’t tolerate fin, am I screwed?

      in Finasteride  116 upvotes 1 year ago
      The user experienced sexual side effects from a topical finasteride and minoxidil combo and stopped using it after three weeks. They plan to use foam minoxidil nightly to slow hair loss and seek alternative treatments that don't affect sexual health.

      community Personal results (1mg finasteride + 10.000mcg biotine) after almost 3 years. Not as impressive as some here, but maybe provides a more realistic view.

      in Progress Pictures  479 upvotes 4 years ago
      Jericho1017 shared their hair regrowth results after nearly 3 years using 1mg finasteride and 10,000mcg biotin daily, with noticeable improvement after 1.5 years and no significant side effects except for watery semen. Some users suggested adding minoxidil and microneedling to improve results, but Jericho1017 is currently content with their progress and not looking to add more treatments.