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      community New potential hair loss treatment (news release)

      in Treatment  187 upvotes 5 years ago
      New potential hair loss treatment uses molecules from hairy moles to stimulate follicle growth. Topical solution requires less frequent application, like Botox injections a few times per year.

      community Oral Finasteride 1.25mg - 9 Months

      in Update  52 upvotes 10 months ago
      The user has been taking oral finasteride 1.25mg daily for 9 months but is still experiencing hair recession. They plan to try topical minoxidil and consider oral minoxidil and dutasteride if needed.

      community Am I missing something with pp405?

      in Research/Science  32 upvotes 1 year ago
      PP405 is discussed as a potential hair growth stimulant, possibly more effective than minoxidil, but not a cure for hair loss. There is skepticism about its ability to regrow "deadzones," and concerns about its impact on those with hair transplants.

      community Mesenchymal Stem Cell Therapy (Exosome) Before & After

      in Treatment  2 upvotes 2 years ago
      A user's father experienced hair regrowth and other health improvements after two IV exosome treatments. The user also had four rounds of exosome therapy, noting significant hair regrowth and relief from headaches, but no change in gray hair.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  44 upvotes 6 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community Oral 1mg Finesteride 2mg Minoxidil

      in Chat  484 upvotes 2 months ago
      The user experienced significant hair regrowth using 1mg finasteride and 2mg minoxidil daily, along with Nizoral shampoo and rosemary oil. They are curious about further improving hair density and whether increasing the minoxidil dose would help.

      community How is this even possible that there is no cure till now

      in Technology  155 upvotes 3 months ago
      There is no permanent cure for hair loss; treatments like finasteride, minoxidil, and hair transplants require ongoing use and are not universally effective. Genetic complexity and financial incentives for ongoing treatments hinder the development of a definitive cure.

      community New Light Therapy Can Suppress a Key Marker of Hair Loss by 92%

      in Research/Science  201 upvotes 4 months ago
      A new light therapy claims to reduce hair loss markers by 92% using a specific wavelength range. Users discuss the cost and effectiveness of devices, with some expressing skepticism and others considering alternative treatments like red light therapy and vitamin D exposure.

      community A Short Recap on PP405 and AAD 2026

      in Update 4 months ago
      PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

      community dut/min /copper peptides VS PP405 results

      in Technology 4 months ago
      Minoxidil, dutasteride, and copper peptides are used in a tattooing method for hair regrowth, with some users noting better results compared to oral treatments. Copper peptides are considered to have minimal impact, but the method may reduce side effects.

      community Welp - pp405 conference showed nothing

      in Update  77 upvotes 4 months ago
      PP405 shows potential for hair growth by increasing terminal hair and converting vellus hairs, but results are modest and more waiting is needed. It complements existing treatments like minoxidil and finasteride, but won't replace them.

      community It looks like Pelage are giving hints that PP405 is a game changer

      in Chat  239 upvotes 4 months ago
      PP405 is seen as a potential breakthrough for converting vellus hairs to terminal hairs, with users expressing both hope and skepticism. It is compared to treatments like minoxidil and finasteride, with discussions on side effects and marketing concerns.

      community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

      in Research/Science  59 upvotes 4 months ago
      Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

      community TCA 35% chemical peel, don't try this shit at home.

      in Treatment  12 upvotes 5 months ago
      The conversation discusses using a TCA 35% chemical peel on the scalp to potentially improve hair growth by addressing fibrosis and enhancing the effectiveness of topical treatments. The user also mentions trying microneedling and other methods like topical metformin and dutasteride for hair regrowth.

      community Prepare to be disappointed by PP405

      in Research/Science  23 upvotes 5 months ago
      Delayed release oral minoxidil is seen as a promising advancement for hair loss treatment, offering safer, higher doses and more consistent hair follicle stimulation compared to current options. However, it is not expected to replace finasteride or dutasteride, as it does not prevent androgenetic alopecia.

      community The future of hair loss drugs.

      in Research/Science  31 upvotes 6 months ago
      Clascoterone 5% and PP405 are being discussed as potential future treatments for hair loss, with clascoterone nearing phase three completion and PP405 possibly taking a cosmetic route to market. Current treatments like minoxidil, finasteride, and RU58841 are mentioned as effective in slowing hair loss, but a complete cure remains elusive.

      community I had claude create a protocol only using fda approved drugs.

      in Research/Science  4 upvotes 6 months ago
      A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.