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      community Why are more people not using RU58841

      in Product  14 upvotes 2 years ago
      People are not using RU58841 for hair loss because it's not FDA approved, lacks long-term safety data, and is difficult to obtain and verify. They prefer FDA-approved treatments like minoxidil, finasteride, ketoconazole shampoo, and microneedling.

      community Why is everyone not directly advised Dutasteride?

      in Finasteride/Dutasteride  169 upvotes 1 year ago
      Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.

      community Effect of nizoral shampoo on scalp

      in Ketoconazole  27 upvotes 1 year ago
      Nizoral shampoo effectively reduces scalp itchiness and dandruff, particularly for those using minoxidil, and may promote hair growth despite not being FDA-approved for this purpose. Users report significant improvements in scalp health and reduced itchiness with regular use.

      community Chat is this real? Compound called clascoterone

      in Research/Science  588 upvotes 4 months ago
      Clascoterone shows promising results for hair regrowth in men with androgenetic alopecia, with potential FDA approval by 2026. It acts as a topical androgen receptor blocker, offering a new treatment option with minimal side effects compared to existing treatments like finasteride.

      community Summary of Procapil video by Haircafe

      in Minoxidil  2 upvotes 9 months ago
      Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.

      community Why use Finasteride instead of Dutasteride?

      in Finasteride/Dutasteride  39 upvotes 2 years ago
      People are discussing why some choose finasteride over dutasteride for hair loss, noting that while dutasteride is more effective, it's also more expensive, less researched, and potentially has more side effects. Some users shared personal experiences with side effects from both drugs, and others mentioned that finasteride is FDA approved for hair loss, while dutasteride is not, except in Japan.

      community FOL005 claims it's better than Finasteride and Minoxidil.

      in Technology  185 upvotes 1 year ago
      FOL-005 claims to be more effective than Minoxidil and Finasteride but lacks anti-DHT properties, leading to potential reduced efficacy over time. Concerns are raised about misleading marketing and the safety of alternative treatments like Pyrilutamide and Clascoterone.

      community Doctors in Denmark are abseloutely 100% clueless when it comes to hairloss. Is it the same in your country?

      in Finasteride/Dutasteride  58 upvotes 1 month ago
      Doctors in Denmark and other countries often lack knowledge about hair loss treatments like Finasteride and Dutasteride, causing patients to seek prescriptions from multiple doctors or online. Some users report better experiences in countries like Brazil and Korea, where doctors are more informed and willing to prescribe these medications.

      community PP405 could be released before GTA 6

      in Chat  133 upvotes 4 months ago
      PP405 is discussed as a potential hair loss treatment, but its effectiveness and safety are uncertain. Some users express skepticism, while others are hopeful, comparing it to existing treatments like Minoxidil and Finasteride.

      community Reaction to High Dose Minoxidil After Year of Use

      in Minoxidil  8 upvotes 6 years ago
      A male with early-stage hair loss experienced severe side effects, including sexual dysfunction from finasteride and increased heart rate and fatigue from high-dose minoxidil, leading to discontinuation of both treatments. He is now relying on DHT-blocking shampoos and awaiting new treatments.

      community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

      in Research/Science  213 upvotes 1 year ago
      PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

      community How are people getting DUT so easily?

      in Finasteride/Dutasteride  15 upvotes 1 year ago
      Dutasteride is hard to get in Europe due to prescription rules, leading some to consider online pharmacies or travel. Users discuss alternatives like private doctors and compare it to finasteride, expressing concerns about side effects and effectiveness.

      community Concerns about CosmeRNA safety mechanisms

      in Treatment  3 upvotes 3 years ago
      Concerns about CosmeRNA safety mechanisms and potential side effects. Discussion includes comparisons to Fluridil and questions about nanoparticle specificity and siRNA stability.

      community I spoke to the Guy who did the Ru58841 (PSK-3841) research

      in Research/Science  289 upvotes 4 years ago
      The conversation discusses RU58841, a compound for hair loss treatment, which was found to be effective in a 6-month trial but was not pursued due to financial issues or marketability concerns, not safety. Some users are considering crowdfunding to release the research data, while others discuss personal experiences and safety concerns with RU58841.

      community Hair Loss Causes Depression. Not Finasteride.

      in Research/Science  188 upvotes 2 months ago
      Finasteride and Dutasteride do not cause depression or mood disorders; hair loss itself may be a more significant factor. Some users experience side effects from Finasteride, but it is generally well-tolerated.
      Feedback on Hair Repair Clinic 5% Minoxidil Cream vs. Sons 5% Spray

      community Feedback on Hair Repair Clinic 5% Minoxidil Cream vs. Sons 5% Spray

      in General  119 upvotes 3 months ago
      A user is considering switching from a 5% minoxidil spray to a minoxidil cream for easier application and less greasiness. They are inquiring about the Hair Repair Clinic 5% minoxidil cream, which includes optional tretinoin and other ingredients like isopropyl myristate and beeswax.

      community PP405 bandwagon, time to resume the hype train.

      in Treatment  166 upvotes 7 months ago
      PP405 shows promise in hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil, with significant results in just four weeks. The treatment is still in early stages, with further trials needed to determine its long-term effectiveness and optimal dosage.

      community PP405 timeframe ? Could it replace current treatments ?

      in Update  34 upvotes 9 months ago
      PP405 is a potential new hair loss treatment that might replace finasteride and minoxidil, but it is still in clinical trials and may not be available until 2028-2031. There is skepticism about its effectiveness, with only a 20% increase in hair density observed in some participants.